
Isabel Goncalves
Professor

Publications
Displaying of publications. Sorted by year, then title.
Genetic Susceptibility to Mood Disorders and Risk of Stroke : A Polygenic Risk Score and Mendelian Randomization Study
Jiangming Sun, Yan Borné, Andreas Edsfeldt, Yunpeng Wang, Mengyu Pan, et al.
(2023) Stroke
Journal articleAssociation Between History of Adverse Pregnancy Outcomes and Coronary Artery Disease Assessed by Coronary Computed Tomography Angiography
Sofia Sederholm Lawesson, Eva Swahn, Mats Pihlsgård, Therese Andersson, Oskar Angerås, et al.
(2023) JAMA, 329 p.393-404
Journal articleBody weight at age 20 and in midlife is more important than weight gain for coronary atherosclerosis : results from SCAPIS
Göran Bergström, Annika Rosengren, Elin Bacsovics Brolin, John Brandberg, Kerstin Cederlund, et al.
(2023) Atherosclerosis
Journal articleEvaluation of Glycosaminoglycans Biological Age in Cells and Tissues
Chrysostomi Gialeli, Isabel Gonçalves
(2023) Methods in molecular biology (Clifton, N.J.), 2619 p.91-98
Book chapterCoronary artery restenosis and target lesion revascularisation in women by pregnancy history
Moa Pehrson, Andreas Edsfeldt, Giovanna Sarno, Abigail Fraser, Janet W. Rich-Edwards, et al.
(2023) Open Heart, 10
Journal articlePolygenic scores for low lung function and the future risk of adverse health outcomes
Suneela Zaigham, Isabel Gonçalves, Gunnar Engström, Jiangming Sun
(2022) Cardiovascular Diabetology, 21 p.1-10
Journal articleReservoir Pressure Integral Is Independently Associated With the Reduction in Renal Function in Older Adults
Kunihiko Aizawa, Alun D. Hughes, Francesco Casanova, Phillip E. Gates, David M. Mawson, et al.
(2022) Hypertension, 79 p.2364-2372
Journal articleCoronary Artery Restenosis in Women by History of Preeclampsia
Annie Lin, Moa Pehrson, Giovanna Sarno, Abigail Fraser, Janet W. Rich-Edwards, et al.
(2022) Journal of the American Heart Association, 11
Journal articleIncreased proteolytic cleavage of osteoglycin is associated with a stable plaque phenotype and lower risk of cardiovascular events
Dania Al-Sharify, Signe Holm Nielsen, Frank Matthes, Christoffer Tengryd, Jiangming Sun, et al.
(2022) Atherosclerosis, 355 p.8-14
Journal articlePlaque characteristics and biomarkers predicting regression and progression of carotid atherosclerosis
Faisel Khan, Isabel Gonçalves, Angela C. Shore, Andrea Natali, Carlo Palombo, et al.
(2022) Cell Reports Medicine, 3
Journal articleDetecting the vulnerable carotid plaque : The Carotid Artery Multimodality imaging Prognostic study design
Luna Gargani, Matteo Baldini, Raffaella Berchiolli, Ida Rebecca Bort, Giancarlo Casolo, et al.
(2022) Journal of Cardiovascular Medicine, 23 p.466-473
Journal articleDynamic epigenetic age mosaicism in the human atherosclerotic artery
Silvio Zaina, Manel Esteller, Isabel Gonçalves, Gertrud Lund
(2022) PLoS ONE, 17
Journal articleOsteomodulin Gene Expression Is Associated with Plaque Calcification, Stability, and Fewer Cardiovascular Events in the CPIP Cohort
Isabel Gonçalves, Loureen Oduor, Frank Matthes, Narjess Rakem, Jakob Meryn, et al.
(2022) Stroke, 53 p.79-84
Journal articleSkin autofluorescence, a measure of tissue accumulation of advanced glycation end products, is associated with subclinical atherosclerosis in coronary and carotid arteries
Jingxue Pan, Xue Bao, Isabel Gonçalves, Amra Jujić, Gunnar Engström
(2022) Atherosclerosis, 345 p.26-32
Journal articleHigh levels of autoantibodies against apoB100 p210 are associated with lower incidence of atrial fibrillation in women
Kari Anne Sveen, Gustav Smith, Harry Björkbacka, Marju Orho-Melander, Gunnar Engström, et al.
(2022) Journal of Internal Medicine, 291 p.207-217
Journal articleCould targeting the macrophage urokinase-type plasminogen activator receptor be a bullseye for PET imaging of atherosclerotic plaque inflammation?
Jason M. Tarkin, Isabel Gonçalves
(2022) Atherosclerosis, 352 p.80-82
Journal article (comment)Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification
Nikolaos T Skenteris, Till Seime, Anna Witasp, Eva Karlöf, Grzegorz B Wasilewski, et al.
(2022) Clinical and Translational Medicine, 12 p.1-22
Journal articleInterferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques
Andreas Edsfeldt, Maarten Swart, Pratibha Singh, Lea Dib, Jiangming Sun, et al.
(2022) European Heart Journal, 43 p.1864-1877
Journal articleSilencing of STE20-type kinase STK25 in human aortic endothelial and smooth muscle cells is atheroprotective
Emmelie Cansby, Sima Kumari, Mara Caputo, Ying Xia, Rando Porosk, et al.
(2022) Communications Biology, 5 p.1-14
Journal articleAssociations of Red Cell Distribution Width With Coronary Artery Calcium in the General Population
Jingxue Pan, Yan Borné, Isabel Gonçalves, Margaretha Persson, Gunnar Engström
(2022) Angiology, 73 p.445-452
Journal articleSoluble CD40 receptor is a biomarker of the burden of carotid artery atherosclerosis in subjects at high cardiovascular risk
Simone Leonetti, Domenico Tricò, Lorenzo Nesti, Simona Baldi, Michaela Kozakova, et al.
(2022) Atherosclerosis, 343 p.1-9
Journal articleCirculating Hepatocyte Growth Factor Reflects Activation of Vascular Repair in Response to Stress
Yihong Chen, Junyan Shen, Anna Hultgårdh Nilsson, Isabel Goncalves, Andreas Edsfeldt, et al.
(2022) JACC: Basic to Translational Science, 7 p.747-762
Journal articleCardiovagal Function Measured by the Deep Breathing Test : Relationships With Coronary Atherosclerosis
Gunnar Engström, Viktor Hamrefors, Artur Fedorowski, Anders Persson, Maria E Johansson, et al.
(2022) Journal of the American Heart Association, 11
Journal articleSub-micrometer morphology of human atherosclerotic plaque revealed by synchrotron radiation-based μCT—A comparison with histology
My Truong, Till Dreier, Johan Wasselius, Lena Sundius, Ana Persson, et al.
(2022) PLoS ONE, 17 p.1-18
Journal articleEpigenome-Wide Histone Acetylation Changes in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes and Atherosclerotic Disease
Pradeep Bompada, Isabel Goncalves, Chuanyan Wu, Rui Gao, Jiangming Sun, et al.
(2021) Biomedicines, 9
Journal articleThe potential role of T2*-weighted multi-echo data image combination as an imaging marker for intraplaque hemorrhage in carotid plaque imaging
My Truong, Claes Håkansson, Makda HaileMichael, Jonas Svensson, Jimmy Lätt, et al.
(2021) BMC Medical Imaging, 21
Journal articleDiverse ultrastructural landscape of atherosclerotic endothelium
Ewelina Kluza, Thijs J. Beldman, Annelie Shami, Edwin R. Scholl, Tsveta S. Malinova, et al.
(2021) Atherosclerosis, 339 p.35-45
Journal articleExtracellular matrix: paving the way to the newest trends in atherosclerosis
Chrysostomi Gialeli, Annelie Shami, Isabel Gonçalves
(2021) Current Opinion in Lipidology, 32 p.277-285
Journal articleCarotid atherosclerosis, changes in tissue remodeling and repair in patients with aortic coarctation
Joanna Hlebowicz, Johan Holm, Sandra Lindstedt, Isabel Goncalves, Jan Nilsson
(2021) Atherosclerosis, 335 p.47-52
Journal articlePrevalence of Subclinical Coronary Artery Atherosclerosis in the General Population
Göran Bergström, Margaretha Persson, Martin Adiels, Elias Björnson, Carl Bonander, et al.
(2021) Circulation, 144 p.916-929
Journal articleSoluble CD40 levels in plasma are associated with cardiovascular disease and in carotid plaques with a vulnerable phenotype
Annelie Shami, Andreas Edsfeldt, Eva Bengtsson, Jan Nilsson, Angela C. Shore, et al.
(2021) Journal of Stroke, 23 p.367-376
Journal articlePlaque vulnerability index predicts cardiovascular events : A histological study of an endarterectomy cohort
Isabel Goncalves, Jiangming Sun, Christoffer Tengryd, Mihaela Nitulescu, Ana F. Persson, et al.
(2021) Journal of the American Heart Association, 10
Journal articleMaterial Decomposition in Low-Energy Micro-CT Using a Dual-Threshold Photon Counting X-Ray Detector
Rasmus Solem, Till Dreier, Isabel Gonçalves, Martin Bech
(2021) Frontiers in Physics, 9
Journal articleThe novel collagen matrikine, endotrophin, is associated with mortality and cardiovascular events in patients with atherosclerosis
S. Holm Nielsen, A. Edsfeldt, C. Tengryd, H. Gustafsson, A. C. Shore, et al.
(2021) Journal of Internal Medicine
Journal articleGlucocorticoid induced TNF receptor family-related protein (GITR) – A novel driver of atherosclerosis
Laura A. Bosmans, Annelie Shami, Dorothee Atzler, Christian Weber, Isabel Gonçalves, et al.
(2021) Vascular Pharmacology, 139
Journal article reviewCell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease
Michael Lacy, Christina Bürger, Annelie Shami, Maiwand Ahmadsei, Holger Winkels, et al.
(2021) Nature Communications, 12
Journal articleClassifications of atherosclerotic plaque components with T1 and T2* mapping in 11.7 T MRI
My Truong, Finn Lennartsson, Adnan Bibic, Lena Sundius, Ana Persson, et al.
(2021) European Journal of Radiology Open, 8 p.100323-100323
Journal articleHuman Atherosclerotic Plaque Progression Is Dependent on Apoptosis According to Bomb-Pulse 14C Dating
Andreas Edsfeldt, Kristina Eriksson Stenström, Jiangming Sun, Nuno Dias, Göran Skog, et al.
(2021) JACC: Basic to Translational Science, 6 p.734-745
Journal articleThe proteoglycan mimecan is associated with carotid plaque vulnerability and increased risk of future cardiovascular death
Christoffer Tengryd, Signe Holm Nielsen, Michele Cavalera, Eva Bengtsson, Federica Genovese, et al.
(2020) Atherosclerosis, 313 p.88-95
Journal articleThe conundrum of asymptomatic carotid stenosis-determinants of decision and evidence
José Fernandes E Fernandes, Luis Mendes Pedro, Isabel Gonçalves
(2020) Annals of Translational Medicine, 8
Journal article reviewExploring the role of extracellular matrix proteins to develop biomarkers of plaque vulnerability and outcome
S. Holm Nielsen, L. Jonasson, K. Kalogeropoulos, M. A. Karsdal, A. L. Reese-Petersen, et al.
(2020) Journal of Internal Medicine, 287 p.493-513
Journal article reviewLegumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Ngoc Nguyen Lunde, Ida Gregersen, Thor Ueland, Christian Shetelig, Sverre Holm, et al.
(2020) Atherosclerosis, 296 p.74-82
Journal articleLow Levels of CD4+CD28null T Cells at Baseline Are Associated With First-Time Coronary Events in a Prospective Population-Based Case-Control Cohort
Lukas Tomas, Eva Bengtsson, Linda Andersson, Wiaam Badn, Christoffer Tengryd, et al.
(2020) Arteriosclerosis, Thrombosis, and Vascular Biology, 40 p.426-436
Journal articleCD163+ macrophages are associated with a vulnerable plaque phenotype in human carotid plaques
Eva Bengtsson, Karin Hultman, Andreas Edsfeldt, Ana Persson, Mihaela Nitulescu, et al.
(2020) Scientific Reports, 10
Journal articleEvidence for a protective role of placental growth factor in cardiovascular disease
Yihong Chen, Anna Hultgårdh Nilsson, Isabel Goncalves, Andreas Edsfeldt, Gunnar Engström, et al.
(2020) Science Translational Medicine, 12
Journal articleReduced oxidized LDL in T2D plaques is associated with a greater statin usage but not with future cardiovascular events
Pratibha Singh, Isabel Goncalves, Christoffer Tengryd, Mihaela Nitulescu, Ana F. Persson, et al.
(2020) Cardiovascular Diabetology, 19
Journal articleSerology assessment of antibody response to SARS-CoV-2 in patients with COVID-19 by rapid IgM/IgG antibody test
Yang De Marinis, Torgny Sunnerhagen, Pradeep Bompada, Anna Bläckberg, Runtao Yang, et al.
(2020) Infection Ecology and Epidemiology, 10
Journal articleCarotid Plaque Morphology is Similar in Patients with Reduced and Normal Renal Function
Caroline Heijl, Fredrik Kahn, Andreas Edsfeldt, Christoffer Tengryd, Jan Nilsson, et al.
(2020) Clinical Medicine Insights: Cardiology, 14
Journal articleGlucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans
Annelie Shami, Dorothee Atzler, Laura A. Bosmans, Holger Winkels, Svenja Meiler, et al.
(2020) European Heart Journal, 41 p.2938-2948
Journal articleS100A9 Links Inflammation and Repair in Myocardial Infarction
Goran Marinković, Duco Steven Koenis, Lisa de Camp, Robert Jablonowski, Naomi Graber, et al.
(2020) Circulation Research, 127 p.664-676
Journal articleElevated IL-27 in patients with acute coronary syndrome is associated with adverse ventricular remodeling and increased risk of recurrent myocardial infarction and cardiovascular death
Helena Grufman, Troels Yndigegn, Isabel Gonçalves, Jan Nilsson, Alexandru Schiopu
(2019) Cytokine, 122
Journal articleCardiovascular organ damage in type 2 diabetes mellitus : The role of lipids and inflammation
Michaela Kozakova, Carmela Morizzo, Isabel Goncalves, Andrea Natali, Jan Nilsson, et al.
(2019) Cardiovascular Diabetology, 18
Journal articleSoluble TRAIL-R2 a marker of plaque cell apoptosis and cardiovascular events.
Isabel Goncalves, Pratibha Singh, Christoffer Tengryd, Michele Cavalera, Ingrid Yao Mattisson, et al.
(2019) Stroke: a journal of cerebral circulation, 50 p.1989-1996
Journal articleActivation of immune responses against the basement membrane component collagen type IV does not affect the development of atherosclerosis in ApoE-deficient mice
J. Vallejo, P. Dunér, F. To, D. Engelbertsen, I. Gonçalves, et al.
(2019) Scientific Reports, 9
Journal articleHigh Levels of Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Carotid Plaque Inflammation and Increased Risk of Ischemic Stroke
Hanna Markstad, Andreas Edsfeldt, Ingrid Yao Mattison, Eva Bengtsson, Pratibha Singh, et al.
(2019) Journal of the American Heart Association, 8
Journal articleMetformin is the key factor in elevated plasma growth differentiation factor-15 levels in type 2 diabetes : A nested, case–control study
Andrea Natali, Lorenzo Nesti, Elena Venturi, Angela C. Shore, Faisel Khan, et al.
(2019) Diabetes, Obesity and Metabolism, 21 p.412-416
Journal articleA biomarker of collagen type I degradation is associated with cardiovascular events and mortality in patients with atherosclerosis
S. Holm Nielsen, C. Tengryd, A. Edsfeldt, S. Brix, F. Genovese, et al.
(2019) Journal of Internal Medicine, 285 p.118-123
Journal articleTransthyretin expression in the postischemic brain
Daniela Talhada, Isabel Gonçalves, Cecília Reis Santos, Karsten Ruscher
(2019) PLoS ONE, 14
Journal articleSubclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy
P. Saliba-Gustafsson, M. Pedrelli, K. Gertow, O. Werngren, V. Janas, et al.
(2019) Journal of Internal Medicine, 286 p.660-675
Journal articleCartilage Oligomeric Matrix Protein Associates With a Vulnerable Plaque Phenotype in Human Atherosclerotic Plaques
Karin Hultman, Andreas Edsfeldt, Harry Björkbacka, Pontus Dunér, Lena Sundius, et al.
(2019) Stroke, 50 p.3289-3292
Journal articleInhibition of pro-inflammatory myeloid cell responses by short-term S100A9 blockade improves cardiac function after myocardial infarction
Goran Marinković, Helena Grauen Larsen, Troels Yndigegn, Istvan Adorjan Szabo, Razvan Gheorghita Mares, et al.
(2019) European Heart Journal, 40 p.2713-2723
Journal articleThe soluble receptor for advanced glycation end-products (sRAGE) has a dual phase-dependent association with residual cardiovascular risk after an acute coronary event.
Helena Grauen Larsen, Troels Yndigegn, Goran Marinkovic, Anna Helena Maria Grufman, Razvan Mares, et al.
(2019) Atherosclerosis, 287 p.16-23
Journal articleUse of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes : The SUMMIT VIP Study
Angela C Shore, Helen M Colhoun, Andrea Natali, Carlo Palombo, Faisel Khan, et al.
(2018) Diabetes Care, 41 p.2212-2219
Journal articleDistinctive peri-luminal presence of agrin in murine and human carotid atherosclerotic plaques
Uwe Rauch, Eva Bengtsson, Isabel Gonçalves, Anna Hultgårdh-Nilsson
(2018) Histology and Histopathology, 33 p.717-726
Journal articleAltered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques
Lukas Tomas, Andreas Edsfeldt, Inês G Mollet, Ljubica Perisic Matic, Cornelia Prehn, et al.
(2018) European Heart Journal, 39 p.2301-2310
Journal articleSpotty Carotid Plaques Are Associated with Inflammation and the Occurrence of Cerebrovascular Symptoms
Sanela Halak, Gerd Östling, Andreas Edsfeldt, Cecilia Kennbäck, Magnus Dencker, et al.
(2018) Cerebrovascular Diseases Extra, 8 p.16-25
Journal articleMarkers of basement membrane remodeling are associated with higher mortality in patients with known atherosclerosis
Signe Holm Nielsen, Christoffer Tengryd, Andreas Edsfeldt, Susanne Brix, Federica Genovese, et al.
(2018) Journal of the American Heart Association, 7
Journal articleADAMTS-7 is associated with a high-risk plaque phenotype in human atherosclerosis
Eva Bengtsson, Karin Hultman, Pontus Dunér, Giuseppe Asciutto, Peter Almgren, et al.
(2017) Scientific Reports, 7
Journal articleElevated Markers of Death Receptor-Activated Apoptosis are Associated with Increased Risk for Development of Diabetes and Cardiovascular Disease
Ingrid Yao Mattisson, Harry Björkbacka, Maria Wigren, Andreas Edsfeldt, Olle Melander, et al.
(2017) EBioMedicine, 26 p.187-197
Journal articlePlasma stem cell factor levels are associated with risk of cardiovascular disease and death
H Björkbacka, I Yao Mattisson, M Wigren, O Melander, G. N. Fredrikson, et al.
(2017) Journal of Internal Medicine, 282 p.508-521
Journal articleInterferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis
Anusha N. Seneviratne, Andreas Edsfeldt, Jennifer E. Cole, Christina Kassiteridi, Maarten Swart, et al.
(2017) Circulation, 136 p.1140-1154
Journal articleCirculating GDF-15 levels predict future secondary manifestations of cardiovascular disease explicitly in women but not men with atherosclerosis
Aisha Gohar, Isabel Gonçalves, Joyce Vrijenhoek, Saskia Haitjema, Ian van Koeverden, et al.
(2017) International Journal of Cardiology, 241 p.430-436
Journal articleAssociation between renin and atherosclerotic burden in subjects with and without type 2 diabetes
Isabel Gonçalves, Andreas Edsfeldt, Helen M. Colhoun, Angela C. Shore, Carlo Palombo, et al.
(2016) BMC Cardiovascular Disorders, 16 p.1-10
Journal articleEndarterectomy patients with elevated levels of circulating IL-16 have fewer cardiovascular events during follow-up
Caitríona Grönberg, Giuseppe Asciutto, Ana Persson, Gunilla Nordin Fredrikson, Jan Nilsson, et al.
(2016) Cytokine, 85 p.137-139
Journal articleElevated CA125 is associated with incident heart failure and increased mortality in patients with acute coronary syndrome
T. Yndigegn, Anna Helena Maria Grufman, D. Erlinge, J Nilsson, I. Goncalves, et al.
(2016) European Heart Journal, 37 p.1392-1393
Conference paper: abstractApolipoprotein B-100 Antibody Interaction With Atherosclerotic Plaque Inflammation and Repair Processes.
Giuseppe Asciutto, Maria Wigren, Gunilla Nordin Fredrikson, Ingrid Yao Mattisson, Caitriona Grönberg, et al.
(2016) Stroke: a journal of cerebral circulation
Journal articleDecreased levels of stem cell factor in subjects with incident coronary events.
Maria Wigren, Sara Rattik, Karin Hultman, Harry Björkbacka, Gunilla Nordin Fredrikson, et al.
(2016) Journal of Internal Medicine, 279 p.180-191
Journal articleGlucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.
Lisa Berglund, Valeriya Lyssenko, Claes Ladenvall, Olga Kotova, Andreas Edsfeldt, et al.
(2016) Diabetes, 65 p.239-254
Journal articleDetermining carotid plaque vulnerability using ultrasound center frequency shifts.
Tobias Erlöv, Magnus Cinthio, Andreas Edsfeldt, Simon Segstedt, Nuno Dias, et al.
(2016) Atherosclerosis, 246 p.293-300
Journal articleHigh Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy.
Andreas Edsfeldt, Eva Bengtsson, Giuseppe Asciutto, Pontus Dunér, Harry Björkbacka, et al.
(2016) Cerebrovascular Diseases, 41 p.199-203
Journal articleHigh levels of cathepsin D and cystatin B are associated with increased risk of coronary events.
Isabel Goncalves, Karin Hultman, Pontus Dunér, Andreas Edsfeldt, Bo Hedblad, et al.
(2016) Open Heart, 3 p.000353-000353
Journal articleAssociations between macrophage colony-stimulating factor and monocyte chemotactic protein 1 in plasma and first-time coronary events : A Nested case-control Study
Alexandru Schiopu, Eva Bengtsson, Isabel Goncalves, Jan Nilsson, Gunilla Nordin Fredrikson, et al.
(2016) Journal of the American Heart Association, 5
Journal articleProinflammatory Role of Sphingolipids and Glycosphingolipids in the Human Atherosclerotic Plaque
Andreas Edsfeldt, Pontus Dunér, Marcus Ståhlman, Ines G Mollet, Giuseppe Asciutto, et al.
(2016) Arteriosclerosis, Thrombosis and Vascular Biology, 36 p.1132-1140
Journal articleGalectin 3 is a powerful risk predictor for recurrent coronary events in acute coronary syndrome patients
A. Schiopu, T. Yndigegn, Anna Helena Maria Grufman, J. Nilsson, I. Goncalves
(2015) European Heart Journal, 36 p.11-11
Conference paper: abstractChronic Inflammation and Atherosclerosis
Jan Nilsson, Isabel Gonçalves, Andreas Edsfeldt
(2015) Early Vascular Aging (EVA) : New Directions in Cardiovascular Protection , p.157-167
Book chapterDystrophin deficiency reduces atherosclerotic plaque development in ApoE-null mice.
Annelie Shami, Anki Knutsson, Pontus Dunér, Uwe Rauch, Eva Bengtsson, et al.
(2015) Scientific Reports, 5
Journal articleLow elastin content of carotid plaques is associated with increased risk of ipsilateral stroke.
Giuseppe Asciutto, Nuno Dias, Andreas Edsfeldt, Mihaela Nitulescu, Ana Persson, et al.
(2015) PLoS ONE, 10
Journal articleDirect association between diet and the stability of human atherosclerotic plaque.
Isabel Goncalves, Elisavet Georgiadou, Sören Mattsson, Göran Skog, Luís Pedro, et al.
(2015) Scientific Reports, 5
Journal articleCoronary liposuction during percutaneous coronary intervention: evidence by near-infrared spectroscopy that aspiration reduces culprit lesion lipid content prior to stent placement.
David Erlinge, Jan Harnek, Isabel Goncalves, Matthias Götberg, James E Muller, et al.
(2015) European Heart Journal-Cardiovascular Imaging, 16 p.316-324
Journal articleHigh Plasma Levels of Heparin-Binding Epidermal Growth Factor Are Associated With a More Stable Plaque Phenotype and Reduced Incidence of Coronary Events.
Sara Rattik, Maria Wigren, Harry Björkbacka, Gunilla Nordin Fredrikson, Bo Hedblad, et al.
(2015) Arteriosclerosis, Thrombosis and Vascular Biology, 35 p.222-228
Journal articleHuman Carotid Plaques With High Levels of Interleukin-16 Are Associated With Reduced Risk for Cardiovascular Events.
Caitriona Grönberg, Eva Bengtsson, Gunilla Nordin Fredrikson, Mihaela Nitulescu, Giuseppe Asciutto, et al.
(2015) Stroke: a journal of cerebral circulation, 46 p.2748-2754
Journal articleElevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.
Isabel Goncalves, Eva Bengtsson, Helen M Colhoun, Angela C Shore, Carlo Palombo, et al.
(2015) Arteriosclerosis, Thrombosis and Vascular Biology, 35 p.1723-1731
Journal articleDetecting the vulnerable plaque in patients.
Isabel Goncalves, H den Ruijter, M Nahrendorf, G Pasterkamp
(2015) Journal of Internal Medicine, 278 p.520-530
Journal article reviewIncreased aldehyde-modification of collagen type IV in symptomatic plaques - A possible cause of endothelial dysfunction.
Pontus Dunér, Isabel Goncalves, Helena Grufman, Andreas Edsfeldt, Fong To, et al.
(2015) Atherosclerosis, 240 p.26-32
Journal articleLow levels of IgG autoantibodies against the apolipoprotein B antigen p210 increases the risk of cardiovascular death after carotid endarterectomy.
Giuseppe Asciutto, Nuno Dias, Andreas Edsfeldt, Ragnar Alm, Gunilla Nordin Fredrikson, et al.
(2015) Atherosclerosis, 239 p.289-294
Journal articleCirculating cytokines reflect the expression of pro-inflammatory cytokines in atherosclerotic plaques.
Andreas Edsfeldt, Helena Grufman, Giuseppe Asciutto, Mihaela Nitulescu, Ana Persson, et al.
(2015) Atherosclerosis, 241 p.443-449
Journal articleATG16L1 Expression in Carotid Atherosclerotic Plaques Is Associated With Plaque Vulnerability.
Joelle Magné, Peter Gustafsson, Hong Jin, Lars Maegdefessel, Kjell Hultenby, et al.
(2015) Arteriosclerosis, Thrombosis and Vascular Biology, 35 p.1226-1235
Journal articleDNA Methylation Dynamics in Human Carotid Plaques After Cerebrovascular Events.
Silvio Zaina, Isabel Goncalves, F Javier Carmona, Antonio Gomez, Holger Heyn, et al.
(2015) Arteriosclerosis, Thrombosis and Vascular Biology, 35 p.1835-1842
Journal articleExpression of fibromodulin in carotid atherosclerotic plaques is associated with diabetes and cerebrovascular events.
Annelie Shami, Christoffer Tengryd, Giuseppe Asciutto, Eva Bengtsson, Jan Nilsson, et al.
(2015) Atherosclerosis, 241 p.701-708
Journal articleMeasures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study
A. C. Shore, H. M. Colhoun, A. Natali, C. Palombo, Gerd Östling, et al.
(2015) Journal of Internal Medicine, 278 p.291-302
Journal articleAtherosclerosis and general principles of arterial imaging.
Isabel Goncalves, Nuno Dias, Peter M Nilsson
(2015) Assessment of Preclinical Organ Damage in Hypertension , p.81-95
Book chapterImaging and Ageing of the Aorta and Large Arteries in the Lower Extremity
Nuno Dias, Isabel Goncalves, Peter Nilsson
(2015) Assessment of Preclinical Organ Damage in Hypertension , p.97-114
Book chapterTreatment with betablockers is associated with higher grey-scale median in carotid plaques
Giuseppe Asciutto, Nuno Dias, Ana Persson, Jan Nilsson, Isabel Goncalves
(2014) BMC Cardiovascular Disorders, 14
Journal articleEvidence for altered inflammatory and repair responses in symptomatic carotid plaques from elderly patients.
Helena Grufman, Alexandru Schiopu, Andreas Edsfeldt, Harry Björkbacka, Mihaela Nitulescu, et al.
(2014) Atherosclerosis, 237 p.177-182
Journal articleA DNA Methylation Map of Human Atherosclerosis.
Silvio Zaina, Holger Heyn, F Javier Carmona, Nuray Varol, Sergi Sayols, et al.
(2014) Circulation: Cardiovascular Genetics, 7 p.692-700
Journal articleImpaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.
Andreas Edsfeldt, Isabel Goncalves, Helena Grufman, Mihaela Nitulescu, Pontus Dunér, et al.
(2014) Arteriosclerosis, Thrombosis and Vascular Biology, 34 p.2143-2150
Journal articleCollagen and related extracellular matrix proteins in atherosclerotic plaque development.
Annelie Shami, Isabel Goncalves, Anna Hultgårdh
(2014) Current Opinion in Lipidology, 25 p.394-399
Journal article reviewPlasma levels of high-sensitive C-reactive protein do not correlate with inflammatory activity in carotid atherosclerotic plaques.
Helena Grufman, Isabel Goncalves, Andreas Edsfeldt, Mihaela Nitulescu, Ana Persson, et al.
(2014) Journal of Internal Medicine, 275 p.127-133
Journal articleLong-term progression of contralateralcarotid artery disease after endarterectomy: is there a need for Duplex surveillance?
Giuseppe Asciutto, Jonatan Wistrand, L Riva, Katarina Björses, Isabel Goncalves, et al.
(2014) International Angiology, 33 p.300-300
Journal article (letter)Histologic and biochemical composition of carotid plaque and its impact on ultrasonographic appearance.
Isabel Goncalves
(2014) Multi-modality atherosclerosis imaging, diagnosis and treatment , p.199-207
Book chapterTreatment with beta-blockers is associated with lower levels of Lp-PLA2 and suPAR in carotid plaques.
Giuseppe Asciutto, Andreas Edsfeldt, Nuno Dias, Jan Nilsson, Cornelia Prehn, et al.
(2013) Cardiovascular Pathology, 22 p.438-443
Journal articleComparison of grey scale median (GSM) measurement in ultrasound images of human carotid plaques using two different softwares.
Gerd Östling, Margaretha Persson, Bo Hedblad, Isabel Goncalves
(2013) Clinical Physiology and Functional Imaging, 33 p.431-435
Journal articleAttenuation of Experimental Atherosclerosis by Interleukin-19.
Stephen Ellison, Khatuna Gabunia, Sheri E Kelemen, Ross N England, Rosario Scalia, et al.
(2013) Arteriosclerosis, Thrombosis and Vascular Biology, 33 p.2316-2324
Journal articlePotential Influence of Diet on Bomb-Pulse Dating of Human Plaque Samples
Elisavet Georgiadou, Isabel Goncalves, Cintia Bertacchi Uvo, Jan Nilsson, Göran Skog, et al.
(2013) Radiocarbon, 55 p.874-884
Journal articleLong-term progression of contralateral carotid artery disease after endarterectomy: is there a need for Duplex surveillance?
Giuseppe Asciutto, Jonatan Wistrand, L Riva, Katarina Björses, Isabel Goncalves, et al.
(2012) International Angiology, 31 p.361-367
Journal articleEvidence Supporting a Key Role of Lp-PLA2-Generated Lysophosphatidylcholine in Human Atherosclerotic Plaque Inflammation.
Isabel Goncalves, Andreas Edsfeldt, Na Young Ko, Helena Grufman, Katarina Berg, et al.
(2012) Arteriosclerosis, Thrombosis and Vascular Biology, 32 p.1505-1505
Journal articleNFAT regulates the expression of AIF-1 and IRT-1: Yin and yang splice variants of neointima formation and atherosclerosis.
Lisa Berglund, Olga Kotova, Peter Osmark, Helena Grufman, Chen Xing, et al.
(2012) Cardiovascular Research, 93 p.414-423
Journal articleSoluble Urokinase Plasminogen Activator Receptor is Associated With Inflammation in the Vulnerable Human Atherosclerotic Plaque.
Andreas Edsfeldt, Mihaela Nitulescu, Helena Grufman, Caitriona Grönberg, Ana Persson, et al.
(2012) Stroke: a journal of cerebral circulation, 43 p.3305-3312
Journal articleActivity Index: a tool to identify active carotid plaques.
Luís Pedro, Isabel Goncalves, R Fernandes e Fernandes, J Seabra, JM Sanches, et al.
(2012) Ultrasound Imaging: Advances and Applications , p.163-175
Book chapterLong-term treatment with low-dose metoprolol CR/XL is associated with increased plaque echogenicity: The Beta-blocker Cholesterol-lowering Asymptomatic Plaque Study (BCAPS).
Gerd Östling, Isabel Goncalves, John Wikstrand, Göran Berglund, Jan Nilsson, et al.
(2011) Atherosclerosis, 215 p.440-445
Journal articleActivator protein-1 in carotid plaques is related to cerebrovascular symptoms and cholesteryl ester content.
Isabel Goncalves, Maria Stollenwerk, Marie Lindholm, Nuno Dias, Luís M Pedro, et al.
(2011) Cardiovascular Pathology, 20 p.36-43
Journal articleLow carotid calcium score is associated with higher levels of glycosaminoglycans, tumor necrosis factor-alpha, and parathyroid hormone in human carotid plaques.
Andreas Edsfeldt, Nuno Dias, Barbara Elmståhl, Markus Müller, Katarina Berg, et al.
(2011) Stroke: a journal of cerebral circulation, 42 p.458-2966
Journal articlePatofysiologi och epidemiologi
Isabel Goncalves, Nuno Dias
(2011) Vård och behandling vid kärlsjukdomar , p.73-80
Book chapterDating Components of Human Atherosclerotic Plaques
Isabel Goncalves, Kristina Stenström, Göran Skog, Sören Mattsson, Mihaela Nitulescu, et al.
(2010) Circulation Research, 106 p.1174-1177
Journal articleCoagulation activation and ultrasound characteristics in patients with carotid artery disease.
Tilo Kölbel, Isabel Goncalves, Nuno Dias, Karin Strandberg, Stefan Acosta, et al.
(2010) Thrombosis Research, 125 p.171-177
Journal articleHemodynamics and jugular venous oxygen saturation during carotid endarterectomy: a comparison between general and locoregional anesthesia.
Nuno Dias, Tilo Kölbel, Isabel Goncalves, Michelle Chew, Jonatan Wistrand, et al.
(2010) International Angiology, 29 p.232-238
Journal articleChanging From Conventional to Eversion Endarterectomy in Carotid Artery Disease-A Safe Transition Process in the Short and Long Term
Jonatan Wistrand, Thomas Mätzsch, Isabel Goncalves, Lorenzo Riva, Nuno Dias
(2010) Vascular and Endovascular Surgery, 44 p.539-544
Journal articleActivation of calpain-1 in human carotid artery atherosclerotic lesions
Isabel Goncalves, Mihaela Nitulescu, Takaomi C. Saido, Nuno Dias, Luis M. Pedro, et al.
(2009) BMC Cardiovascular Disorders, 9
Journal articleIdentification of the target for therapeutic recombinant anti-apoB-100 peptide antibodies in human atherosclerotic lesions.
Isabel Goncalves, Mihaela Nitulescu, Mikko Ares, Gunilla Nordin Fredrikson, Bo Jansson, et al.
(2009) Atherosclerosis, 205 p.96-100
Journal articleImmune responses against fibronectin modified by lipoprotein oxidation and their association with cardiovascular disease.
Pontus Dunér, Fong To, Ragnar Alm, Isabel Goncalves, Gunilla Nordin Fredrikson, et al.
(2009) Journal of Internal Medicine, Feb 14. p.593-603
Journal articleEffects of simvastatin on circulating autoantibodies to oxidized LDL antigens: relation with immune stimulation markers.
Isabel Goncalves, Pierre Cherfan, Ingrid Söderberg, Gunilla Nordin Fredrikson, Lena Jonasson
(2009) Autoimmunity, 42 p.203-208
Journal articleElastin- and Collagen-Rich Human Carotid Plaques Have Increased Levels of the Cysteine Protease Inhibitor Cystatin C.
Isabel Goncalves, Mikko P S Ares, Anna Moberg, Jonatan Moses, Fong To, et al.
(2008) Journal of Vascular Research, 45 p.395-401
Journal articleIncreased Echolucency of Carotid Plaques in Patients With Type 2 Diabetes.
Gerd Östling, Bo Hedblad, Göran Berglund, Isabel Goncalves
(2007) Stroke: a journal of cerebral circulation, 38 p.2074-2078
Journal articleImmunomodulation of atherosclerosis
Jan Nilsson, Gunilla Nordin Fredrikson, Alexandru Schiopu, Isabel Goncalves, KY Chyu, et al.
(2007) The Vulnerable Plaque , p.371-382
Book chapterPode a ultrasonografia carotídea reflectir a composição da placa aterosclerótica vulnerável?
Isabel Goncalves, Luís M Pedro, Nuno Dias, Marie Lindholm, Gunilla Fredrikson, et al.
(2007) Angiologia e Cirurgia Vascular, 3 p.93-96
Journal articleC4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation.
Leendert Trouw, Sara Nilsson, Isabel Goncalves, Göran Landberg, Anna Blom
(2005) Journal of Experimental Medicine, 201 p.1937-1948
Journal articleHumoral Immune Response Against Defined Oxidized Low-Density Lipoprotein Antigens Reflects Structure and Disease Activity of Carotid Plaques.
Isabel Goncalves, Marie-Louise M Gronholdt, Ingrid Söderberg, Mikko Ares, Borge G Nordestgaard, et al.
(2005) Arteriosclerosis, Thrombosis and Vascular Biology, 25 p.1250-1255
Journal articleKan man hitta instabila karotisplack med ultraljud?
Isabel Goncalves, Jan Nilsson, Mikko Ares
(2005) Kärilet, 17 p.4-6
Journal articleElastin and calcium rather than collagen or lipid content are associated with echogenicity of human carotid plaques.
Isabel Goncalves, Marie Lindholm, Luis M Pedro, Nuno Dias, José Fernandes e Fernandes, et al.
(2004) Stroke: a journal of cerebral circulation, 35 p.2795-2800
Journal articleEcholucency of carotid plaques correlates with plaque cellularity.
Isabel Goncalves, J. Moses, L. Pedro, N. Dias, J. Fernandes, et al.
(2003) European Journal of Vascular and Endovascular Surgery, 26 p.32-38
Journal articleChanges related to age and cerebrovascular symptoms in the extracellular matrix of human carotid plaques.
Isabel Goncalves, Jonatan Moses, Nuno Dias, Luís M Pedro, José Fernandes e Fernandes, et al.
(2003) Stroke: a journal of cerebral circulation, 34 p.616-622
Journal articleUltrasonographic risk score of carotid plaques
L M Pedro, J Fernandes e Fernandes, M M Pedro, I Goncalves, Nuno Dias, et al.
(2002) European Journal of Vascular and Endovascular Surgery, 24 p.492-498
Journal articleBeta-estradiol effect on erythrocyte aggregation--a controlled in vitro study
Isabel Goncalves, C Saldanha, J Martins e Silva
(2001) Clinical Hemorheology and Microcirculation, 25 p.127-134
Journal articleCarotid plaque characterisation. A new ultrasonographic activity index
Luís Pedro, M M Pedro, Isabel Goncalves, Nuno Dias, R Fernandes e Fernandes, et al.
(2001) Cerebrovascular Diseases, 11 p.5-5
Conference paper: abstractComputer-assisted carotid plaque analysis: characteristics of plaques associated with cerebrovascular symptoms and cerebral infarction
L M Pedro, M M Pedro, Isabel Goncalves, T F Carneiro, C Balsinha, et al.
(2000) European Journal of Vascular and Endovascular Surgery, 19 p.118-123
Journal articleVery low-density lipoprotein activates nuclear factor-kappaB in endothelial cells
W Dichtl, L Nilsson, Isabel Goncalves, Mikko Ares, C Banfi, et al.
(1999) Circulation Research, 84 p.1085-1094
Journal articlePlaca de ateroma da bifurcacao carotidea: como identificar a lesao "activa"?
L M Pedro, M M Pedro, Isabel Goncalves, T F Carneiro, C Balsinha, et al.
(1999) Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 18 p.699-708
Journal articleOxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression in vascular smooth muscle cells
Wolfgang Dichtl, Ann Stiko, Per Eriksson, Isabel Goncalves, Frederico Calara, et al.
(1999) Arteriosclerosis, Thrombosis, and Vascular Biology, 19 p.32-3025
Journal articleOubain role on erythrocyte/fibrinogen interaction
Isabel Goncalves, Rui Mesquita, C Saldanha, J Martins e Silva
(1999) Blood Coagulation and Fibrinolysis, 10 p.107-107
Conference paper: abstractEthanol and erythrocyte membrane interaction: a hemorheologic perspective.
Rui Mesquita, Isabel Goncalves, S Dias, Luís Sargento, C Saldanha, et al.
(1999) Clinical Hemorheology and Microcirculation, 21 p.95-98
Journal articleEstudo in vivo da parede arterial no aterosclerose: impacto dosfactores de risco e correlação com a cardiopatia isquernica
M M Pedro, L M Pedro, R Fernandes e Fernandes, T F Carneiro, C Balsinha, et al.
(1998) , p.31-31
Conference paper: abstractFibrinogénio e agregação eritrocitária
Rui Mesquita, Isabel Goncalves, C Saldanha, J Martins e Silva
(1998) Boletim da SPHM (Sociedade Portuguesa de Hemorreologia e Microcirculação), 13 p.28-28
Journal article (comment)The Evaluation Of The Arterial Wall By High Definition Ultrassonography: The Impact Of The Atherosclerotic Risk Factors And its Relation With Advanced Forms of the Disease
M M Pedro, L M Pedro, R Fernandes e Fernandes, T F Carneiro, C Balsinha, et al.
(1997) , p.62-62
Conference paper: abstractUma janela para a aterosclerose: A Ecografia de alta definição no estudo da parede arterial
Luís Pedro, M M Pedro, R Fernandes e Fernandes, T F Carneiro, C Balsinha, et al.
(1997) Jornal das Ciências Médicas, 161 p.37-61
Journal articleEfeito in vitro do etanolna membrana eritrocitária
Luís Sargento, Isabel Goncalves, Rui Mesquita, Sonia Pimentel, C Saldanha, et al.
(1995) Boletim da SPHM (Sociedade Portuguesa de Hemorreologia e Microcirculação), 10 p.22-22
Journal article (comment)