Holger Luthman
Professor
Publications
Displaying of publications. Sorted by year, then title.
Epigenome-wide cross-tissue correlation of human bone and blood DNA methylation–can blood be used as a surrogate for bone?
Parvaneh Ebrahimi, Holger Luthman, Fiona E. McGuigan, Kristina E. Akesson
(2021) Epigenetics, 16 p.92-105
Journal articleGlucose-dependent insulinotropic polypeptide (GIP) and GIP receptor (GIPR) genes : An association analysis of polymorphisms and bone in young and elderly women
Gaurav Garg, Fiona E. McGuigan, Jitender Kumar, Holger Luthman, Valeriya Lyssenko, et al.
(2016) Bone Reports, 4 p.23-27
Journal articleVariation in the PTH2R gene is associated with age-related degenerative changes in the lumbar spine.
Kristina Åkesson, Max Tenne, Paul Gerdhem, Holger Luthman, Fiona McGuigan
(2015) Journal of Bone and Mineral Metabolism, 33 p.9-15
Journal articleC-reactive protein, bone loss, fracture, and mortality in elderly women: a longitudinal study in the OPRA cohort.
Sofia Berglundh, Linnea Malmgren, Holger Luthman, Fiona McGuigan, Kristina Åkesson
(2015) Osteoporosis International, 26 p.727-735
Journal articlePolymorphisms in inflammation associated genes ALOX15 and IL-6 are associated with bone properties in young women and fracture in elderly.
Maria Herlin, Fiona McGuigan, Holger Luthman, Kristina Åkesson
(2015) Bone, 79 p.105-109
Journal articleVariations in apolipoprotein D and sigma non-opioid intracellular receptor 1 genes with relation to risk, severity and outcome of ischemic stroke
Håkan Lövkvist, Ann-Cathrin Jönsson, Holger Luthman, Katarina Jood, Christina Jern, et al.
(2014) BMC Neurology, 14
Journal articleVariation in the MC4R Gene Is Associated with Bone Phenotypes in Elderly Swedish Women.
Gaurav Garg, Jitender Kumar, Fiona McGuigan, Martin Ridderstråle, Paul Gerdhem, et al.
(2014) PLoS ONE, 9
Journal articleHTR1A a Novel Type 1 Diabetes Susceptibility Gene on Chromosome 5p13-q13
Samina Asad, Pernilla Nikamo, Alexandra Gyllenberg, Hedvig Bennet, Ola Hansson, et al.
(2012) PLoS ONE, 7
Journal articleLinkage study of embryopathy-Polygenic inheritance of diabetes-induced skeletal malformations in the rat
Niklas Nordquist, Holger Luthman, Ulf Pettersson, Ulf J. Eriksson
(2012) Reproductive Toxicology, 33 p.297-307
Journal articleGenome-wide linkage analysis in families with infantile hypertrophic pyloric stenosis indicates novel susceptibility loci
Anna Svenningsson, Cilla Soderhall, Sofia Persson, Fredrik Lundberg, Holger Luthman, et al.
(2012) Journal of Human Genetics, 57 p.115-121
Journal articleA large-sample assessment of possible association between ischaemic stroke and rs12188950 in the PDE4D gene.
Håkan Lövkvist, Sandra Olsson, Peter Höglund, Olle Melander, Christina Jern, et al.
(2012) European Journal of Human Genetics, 20 p.783-789
Journal articleA common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
Thomas Koeck, Anders H Olsson, Marloes Dekker Nitert, Vladimir Sharoyko, Claes Ladenvall, et al.
(2011) Cell Metabolism, 13 p.80-91
Journal articleIdentification of Candidate Gene Regions in the Rat by Co-Localization of QTLs for Bone Density, Size, Structure and Strength.
Sofia Lagerholm, Hee-Bok Park, Holger Luthman, Marc Grynpas, Fiona McGuigan, et al.
(2011) PLoS ONE, 6
Journal articleGenetic loci for bone architecture determined by three-dimensional CT in crosses with the diabetic GK rat.
Sofia Lagerholm, Hee-Bok Park, Holger Luthman, Mats A Nilsson, Fiona McGuigan, et al.
(2010) Bone, 47 p.1039-1047
Journal articleOverexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes.
Anders Rosengren, Ramunas Jokubka, Damon Tojjar, Charlotte Granhall, Ola Hansson, et al.
(2010) Science (New York, N.Y.), 327 p.217-220
Journal articleParathyroid hormone gene variation contributes to femoral neck geometry
Fiona McGuigan, Max Tenne, Holger Luthman, Henrik Ahlborg, Karl Obrant, et al.
(2009) Bone, 44 p.342-342
Conference paper: abstractGenetic Regulation of Bone Traits Is Influenced by Sex and Reciprocal Cross in F-2 Progeny From GK and F344 Rats
Sofia Lagerholm, Luo-Sheng Li, Hong Jiao, Hee-Bok Park, Claes Ohlsson, et al.
(2009) Journal of Bone and Mineral Research, 24 p.1066-1074
Journal articleComparative sequence analysis of the non-protein-coding mitochondrial DNA of inbred rat strains.
Avinash Abhyankar, Hee-Bok Park, Giancarlo Tonolo, Holger Luthman
(2009) PLoS ONE, 4
Journal articleDisruption of TFB1M impairs insulin secretion in beta cells
Thomas Köck, Marloes Dekker Nitert, A Olsson, Olga Kotova, Jelena Stamenkovic, et al.
(2009) Diabetologia, 52 p.116-116
Conference paper: abstractHyperactivity in adrenergic signalling via alpha2A receptors contributes to human type 2 diabetes
Anders Rosengren, Ramunas Jokubka, Damon Tojjar, Charlotte Granhall, Jonatan Tuncel, et al.
(2009) Diabetologia, 52 p.108-108
Conference paper: abstractPositional cloning of the Igl genes controlling rheumatoid factor production and allergic bronchitis in rats
Carola Rintisch, Jacqueline Ameri, Peter Olofsson, Holger Luthman, Rikard Holmdahl
(2008) Proceedings of the National Academy of Sciences, 105 p.14005-14010
Journal articleA metabolic comparison of glucose-responsive INS-1 832/13 and glucose-nonresponsive INS-1 832/2 cells
Vladimir Sharoyko, Karl Bacos, Avinash Abhyankar, Cecilia Nagorny, Hindrik Mulder, et al.
(2008) Diabetologia, 51 p.203-204
Conference paper: abstractCharacterization and Genetic Mapping of Bone Size Phenotypes in GK and F344 Rats Using a New 3D CT Method.
Sofia Lagerholm, Holger Luthman, M Nilsson, Kristina Åkesson
(2008) Journal of Bone and Mineral Research, 23 p.492-492
Conference paper: abstractVariation in the Osteocalcin Gene: Association Study of BMD, Fracture and Changes in Body Fat Mass in Elderly Women.
Fiona McGuigan, Kaisa Ivaska, P. Gerdhem, Holger Luthman, Kristina Åkesson
(2008) Journal of Bone and Mineral Research, 23 p.296-296
Conference paper: abstractNerve compression induces activating transcription factor 3 in neurons and Schwann cells in diabetic rats.
Lars Dahlin, Lena Stenberg, Holger Luthman, Niels Thomsen
(2008) NeuroReport, 19 p.987-990
Journal articleVariation in the bone morphogenetic protein-2 gene: effects on fat and lean body mass in young and elderly women.
Fiona McGuigan, Emma Larzenius, Mattias Callréus, Paul Gerdhem, Holger Luthman, et al.
(2008) European Journal of Endocrinology, 158 p.661-668
Journal articleIschaemic stroke in hypertensive patients is associated with variations in the PDE4D genome region.
Håkan Lövkvist, Jan Gustav Smith, Holger Luthman, Peter Höglund, Bo Norrving, et al.
(2008) European Journal of Human Genetics, 16 p.1117-1125
Journal articleEpigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion.
Charlotte Ling, S Del Guerra, R Lupi, Tina Rönn, Charlotte Granhall, et al.
(2008) Diabetologia, 51 p.615-622
Journal articleGenetic variation in the PTH pathway and bone phenotypes in elderly women: Evaluation of PTH, PTHLH, PTHR1 and PTHR2 genes.
Max Tenne, Fiona McGuigan, Lisa Jansson, Paul Gerdhem, Karl Obrant, et al.
(2008) Bone, 42 p.719-727
Journal articleVariation in the BMP2 gene: Bone mineral density and ultrasound in young adult and elderly women
Fiona McGuigan, Emma Larzenius, Mattias Callréus, Paul Gerdhem, Holger Luthman, et al.
(2007) Calcified Tissue International, 81 p.254-262
Journal articleHigh-resolution QTL Analysis Reveals Multiple Diabetes Susceptibility Loci Mapped to Intervals less than 800-kb in the Species Conserved Niddm1i of the GK Rat.
Charlotte Granhall, Hee-Bok Park, Hossein Fakhrai-Rad, Holger Luthman
(2006) Genetics, 174 p.1565-1572
Journal articleSeparately inherited defects in insulin exocytosis and beta-cell glucose metabolism contribute to type 2 diabetes.
Charlotte Granhall, Anders Rosengren, Erik Renström, Holger Luthman
(2006) Diabetes, 55 p.3494-3500
Journal articleIncreased renal arterial resistance predicts the course of renal function in type 2 diabetes with microalbuminuria
R Nosadini, M Velussi, E Brocco, C Abaterusso, A Carraro, et al.
(2006) Diabetes, 55 p.234-239
Journal articleSimvastatin maintains steady patterns of GFR and improves AER and expression of slit diaphragm proteins in type II diabetes
G. Tonolo, M. Velussi, E. Brocco, C. Abaterusso, A. Carraro, et al.
(2006) Kidney International, 70 p.177-186
Journal articleImmune-mediated beta-cell destruction in vitro and in vivo-A pivotal role for galectin-3.
Allan E Karlsen, Zenia M Størling, Thomas Sparre, Martin R Larsen, Amer Mahmood, et al.
(2006) Biochemical and Biophysical Research Communications, 344 p.406-415
Journal articleCrohn's disease associated CARD15 (NOD2) variants are not involved in the susceptibility to type 1 diabetes
P Ghandil, C Chelala, D Dubois-Laforgue, V Senee, S Caillat-Zucman, et al.
(2005) Molecular Genetics and Metabolism, 86 p.379-383
Journal articleAltered transcapillary escape of albumin and microalbuminuria reflects two different pathogenetic mechanisms
R Nosadini, M Velussi, E Brocco, C Abaterusso, F Piarulli, et al.
(2005) Diabetes, 54 p.228-233
Journal articleMHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction
Maria Swanberg, O Lidman, L Padyukov, P Eriksson, E Akesson, et al.
(2005) Nature Genetics, 37 p.486-494
Journal articleUnconditional two-locus nonparametric linkage analysis
Lars Ängquist, Dragi Anevski, Holger Luthman
(2005) Preprint without journal information
Journal articlePrevalence of Stroke and Vascular Risk Factors among First-Degree Relatives of Stroke Patients and Control Subjects.
Arne Lindgren, Håkan Lovkvist, Björn Hallström, Peter Höglund, Ann-Cathrin Jönsson, et al.
(2005) Cerebrovascular Diseases, 20 p.381-387
Journal articleGenetic and functional evaluation of an interleukin-12 polymorphism (IDDM18) in families with type 1 diabetes
R Bergholdt, P Ghandil, J Johannesen, OP Kristiansen, I Kockum, et al.
(2004) Journal of Medical Genetics, 41
Journal articleInteraction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families
P Holm, B Rydlander, Holger Luthman, I Kockum
(2004) Diabetes, 53 p.1584-1591
Journal articleGENOME-WIDE LINKAGE ANALYSIS FOR HYPOSPADIAS SUSCEPTIBILITY GENES.
Louise Frisén, Cilla Söderhäll, Margareta Tapper-Persson, Holger Luthman, Ingrid Kockum, et al.
(2004) Journal of Urology, 172 p.1460-1463
Journal articleNo evidence for linkage in Swedish multiplex T1DM families to IL12B on chromosome 5q33-34
P Holm, Holger Luthman, I Kockum
(2003) Annals of the New York Academy of Sciences, 1005 p.352-355
Journal articleHigh resolution mapping of an arthritis susceptibility locus on rat chromosome 4, and characterization of regulated phenotypes
U Ribbhammar, L Flornes, L Backdahl, Holger Luthman, S Fossum, et al.
(2003) Human Molecular Genetics, 12 p.2087-2096
Journal articleA conformation-dependent epitope in Addison's disease and other endocrinological autoimmune diseases maps to a carboxyl-terminal functional domain of human steroid 21-hydroxylase
Andrej Nikoshkov, Alberto Falorni, Svetlana Lajic, Stefano Laureti, Anna Wedell, et al.
(1999) Journal of Immunology, 162 p.2422-2426
Journal articleGenetic and immunological findings in patients with newly diagnosed insulin-dependent diabetes mellitus
Ingrid Kockum, Å Lernmark, Gisela Dahlquist, A. Falorni, W. A. Hagopian, et al.
(1996) Hormone and Metabolic Research, 28 p.344-347
Journal articleHigh diagnostic accuracy for idiopathic Addison’s disease with a sensitive radiobinding assay for autoantibodies against recombinant human 21-hydroxylase
Alberto Falorni, Andrej Nikoshkov, Stefano Laureti, Eva Grenb�ck, Anna Lena Hulting, et al.
(1995) Journal of Clinical Endocrinology and Metabolism, 80 p.2752-2755
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