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Hindrik Mulder

Hindrik Mulder

Principal investigator

Hindrik Mulder

Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: the GLACIER Study.

Author

  • Frida Renström
  • Robert Koivula
  • Tibor V Varga
  • Göran Hallmans
  • Hindrik Mulder
  • Jose C Florez
  • Frank B Hu
  • Paul Franks

Summary, in English

The association of single nucleotide polymorphisms (SNPs) proximal to CRY2 and MTNR1B with fasting glucose is well established. CRY1/2 and MTNR1B encode proteins that regulate circadian rhythmicity and influence energy metabolism. Here we tested whether season modified the relationship of these loci with blood glucose concentration.

Department/s

  • Genetic and Molecular Epidemiology
  • Diabetes - Molecular Metabolism
  • EXODIAB: Excellence of Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year

2015

Language

English

Pages

997-1005

Publication/Series

Diabetologia

Volume

58

Issue

5

Document type

Journal article

Publisher

Springer

Topic

  • Endocrinology and Diabetes

Status

Published

Research group

  • Genetic and Molecular Epidemiology
  • Diabetes - Molecular Metabolism

ISBN/ISSN/Other

  • ISSN: 1432-0428