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ludc webb

Harry Björkbacka

Researcher

ludc webb

Generalized rank tests for replicated microarray data

Author

  • MLT Lee
  • RJ Gray
  • Harry Björkbacka
  • MW Freeman

Summary, in English

Gene expression data from microarray experiments have been studied using several statistical models. Significance Analysis of Microarrays (SAM), for example, has proved to be useful in analyzing microarray data. In the spirit of the SAM procedures, we develop permutation based rank-tests for generalized Wilcoxon ranksum test for two-group comparisons of replicated microarray data. Also, for microarray experiments with randomized block design, we consider generalized signed rank test. The statistical analysis software package is written in R and is freely available in a package.

Department/s

  • Cardiovascular Research - Immunity and Atherosclerosis

Publishing year

2005

Language

English

Publication/Series

Statistical Applications in Genetics and Molecular Biology

Volume

4

Issue

1

Document type

Journal article

Publisher

Berkeley Electronic Press

Topic

  • Cardiac and Cardiovascular Systems

Keywords

  • blocked comparisons
  • rank tests
  • permutation tests

Status

Published

Research group

  • Cardiovascular Research - Immunity and Atherosclerosis

ISBN/ISSN/Other

  • ISSN: 2194-6302