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IL-25 Inhibits Atherosclerosis Development in Apolipoprotein E Deficient Mice.

Author:
  • Polyxeni Mantani
  • Pontus Dunér
  • Eva Bengtsson
  • Ragnar Alm
  • Irena Ljungcrantz
  • Ingrid Söderberg
  • Lena Sundius
  • Fong To
  • Jan Nilsson
  • Harry Björkbacka
  • Gunilla Nordin Fredrikson
Publishing year: 2015
Language: English
Publication/Series: PLoS ONE
Volume: 10
Issue: 1
Document type: Journal article
Publisher: Public Library of Science

Abstract english

IL-25 has been implicated in the initiation of type 2 immunity and in the protection against autoimmune inflammatory diseases. Recent studies have identified the novel innate lymphoid type 2 cells (ILC2s) as an IL-25 target cell population. The purpose of this study was to evaluate if IL-25 has any influence on atherosclerosis development in mice.

Keywords

  • Cardiac and Cardiovascular Systems

Other

Published
  • Experimental Cardiovascular Research Unit
  • ISSN: 1932-6203
E-mail: fong [dot] to [at] med [dot] lu [dot] se

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