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Falastin Salami

Research project participant

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DETECTION OF LACTOBACILLI IN MONTHLY MAIL-IN STOOL SAMPLES FROM 3-18 MONTHS OLD INFANTS AT GENETIC RISK FOR TYPE 1 DIABETES

Author

  • F Salami
  • M Abels
  • H Hyöty
  • F Vaziri-Sani
  • Carin Andrén Aronsson
  • K Vehik
  • A Delli
  • Wa Hagopian
  • M Rewers
  • Ag Ziegler
  • O Simell
  • B Akolkar
  • J Krischer
  • J She
  • A Lernmark

Summary, in English

The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Diabetes in the Young) study. Total lactobacilli content varied markedly between 5 and 16,800 ng/g feces in the three clinical sites within and between individuals especially in infants. L.plantarum also varied markedly intra- and inter-individually from <0.5 - 736 ng/g feces. A higher variability of total lactobacilli was found before 10 months of age than after in the three different clinical sites. Sweden had the lowest total lactobacilli content compared to Colorado and Finland while the L.plantarum content was higher in Sweden. Mail-in stool samples from infants should prove useful in analyzing probiotics in childhood.

Department/s

  • EXODIAB: Excellence of Diabetes Research in Sweden
  • Department of Clinical Sciences, Malmö

Publishing year

2012

Language

English

Pages

135-144

Publication/Series

International journal of probiotics & prebiotics

Volume

7

Issue

3-4

Document type

Journal article

Publisher

New Century Health Publishers

Topic

  • Microbiology in the medical area

Status

Published

ISBN/ISSN/Other

  • ISSN: 1555-1431