Eva Degerman
Research team manager
Publications
Displaying of publications. Sorted by year, then title.
Betahistine prevents development of endolymphatic hydrops in a mouse model of insulin resistance and diabetes
Ann-Ki Pålbrink, René In 't Zandt, Måns Magnusson, Eva Degerman
(2023) Acta Oto-Laryngologica , p.1-7
Journal articleAMPKβ isoform expression patterns in various adipocyte models and in relation to body mass index
Franziska Kopietz, Eva Degerman, Olga Göransson
(2022) Frontiers in Physiology, 13
Journal articleOverexpressed beta cell CART increases insulin secretion in mouse models of insulin resistance and diabetes
Mia Abels, Matteo Riva, Liliya Shcherbina, Ann Helen Thorén Fischer, Elin Banke, et al.
(2022) Peptides, 151
Journal articleInsulin regulates Nedd4-2 via a PKB-dependent mechanism in HEI-OC1 auditory cells-crosstalks with sphingolipid and cAMP signaling
Ann-Ki Pålbrink, Björn Morén, Karin G Stenkula, Måns Magnusson, Eva Degerman
(2022) Acta Oto-Laryngologica, 142 p.6-12
Journal articleEH Domain-Containing 2 Deficiency Restricts Adipose Tissue Expansion and Impairs Lipolysis in Primary Inguinal Adipocytes
Claes Fryklund, Björn Morén, Shrenika Shah, Mario Grossi, Eva Degerman, et al.
(2021) Frontiers in Physiology, 12
Journal articleSecond messengers | Cyclic nucleotide phosphodiesterases
V. C. Manganiello, E. Degerman
(2021) Encyclopedia of Biological Chemistry : Third Edition, 6 p.517-522
Book chapterA-769662 inhibits adipocyte glucose uptake in an AMPK-independent manner
Franziska Kopietz, Yazeed Alshuweishi, Silvia Bijland, Fatmah Alghamdi, Eva Degerman, et al.
(2021) The Biochemical journal, 478 p.633-646
Journal articleInner ear is a target for insulin signaling and insulin resistance : evidence from mice and auditory HEI-OC1 cells
Ann-Ki Pålbrink, Franziska Kopietz, Björn Morén, René In 't Zandt, Federico Kalinec, et al.
(2020) BMJ open diabetes research & care, 8
Journal articleIncreased whole body energy expenditure and protection against diet-induced obesity in Cyp8b1-deficient mice is accompanied by altered adipose tissue features
Ulrika Axling, Michele Cavalera, Eva Degerman, Mats Gåfvels, Gösta Eggertsen, et al.
(2020) Adipocyte, 9 p.587-599
Journal articleInhibition of AMPK activity in response to insulin in adipocytes : involvement of AMPK pS485, PDEs, and cellular energy levels
Franziska Kopietz, Kaja Rupar, Christine Berggreen, Johanna Säll, Didier Vertommen, et al.
(2020) American Journal of Physiology - Endocrinology and Metabolism, 319 p.459-471
Journal articleEndolymphatic hydrops induced by different mechanisms responds differentially to spironolactone : a rationale for understanding the diversity of treatment responses in hydropic inner ear disease
Eva Degerman, René In 't Zandt, Annki Pålbrink, Måns Magnusson
(2019) Acta Oto-Laryngologica, 139 p.685-691
Journal articleInsulin induces Thr484 phosphorylation and stabilization of SIK2 in adipocytes
Johanna Säll, Florentina Negoita, Björn Hansson, Franziska Kopietz, Wilhelm Linder, et al.
(2019) Cellular Signalling, 55 p.73-80
Journal articleAMPK activation by A-769662 and 991 does not affect catecholamine-induced lipolysis in human adipocytes
Franziska Kopietz, Christine Berggreen, Sara Larsson, Johanna Säll, Mikael Ekelund, et al.
(2018) American Journal of Physiology - Endocrinology and Metabolism, 315 p.1075-1085
Journal articleβ-Sarcoglycan Deficiency Reduces Atherosclerotic Plaque Development in ApoE-Null Mice
Vignesh Murugesan, Eva Degerman, Anki Knutsson, Pontus Dunér, Ann-Kristin Holmén-Pålbrink, et al.
(2017) Journal of Vascular Research, 54 p.235-245
Journal articleSalt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals : implications for insulin signalling and glucose uptake in human adipocytes
Johanna Säll, Annie M L Pettersson, Christel Björk, Emma Henriksson, Sebastian Wasserstrom, et al.
(2017) Diabetologia, 60 p.314-323
Journal articleWhite to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function
Youn Wook Chung, Faiyaz Ahmad, Yan Tang, Steven C. Hockman, Hyun Jung Kee, et al.
(2017) Scientific Reports, 7
Journal articleInhibition of phosphodiesterase 3, 4, and 5 induces endolymphatic hydrops in mouse inner ear, as evaluated with repeated 9.4T MRI
Eva Degerman, Rene in 't Zandt, Ann-Kristin Holmén-Pålbrink, Lena Eliasson, Per Cayé-Thomasen, et al.
(2017) Acta Oto-Laryngologica, 137 p.8-15
Journal articleBranched short-chain fatty acids modulate glucose and lipid metabolism in primary adipocytes
Emilia Heimann, Margareta Nyman, Ann-Kristin Holmén-Pålbrink, Karin Lindkvist-Petersson, Eva Degerman
(2016) Adipocyte, 5 p.359-368
Journal articleParathyroid hormone induces adipocyte lipolysis via PKA-mediated phosphorylation of hormone-sensitive lipase.
Sara Larsson, Helena Jones, Olga Göransson, Eva Degerman, Cecilia Holm
(2016) Cellular Signalling, 28 p.204-213
Journal articleCyclic Nucleotide Phosphodiesterases: important signaling modulators and therapeutic targets
F. Ahmad, T. Murata, K. Shimizu, Eva Degerman, D. Maurice, et al.
(2015) Oral Diseases, 21 p.25-50
Journal article reviewVasopressin induces endolymphatic hydrops in mouse inner ear, as evaluated with repeated 9.4 T MRI.
Eva Degerman, René in 't Zandt, Ann-Kristin Holmén-Pålbrink, Måns Magnusson
(2015) Hearing Research, 330 p.119-124
Journal articleSIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes
Emma Henriksson, Johanna Säll, Amelie Gormand, Sebastian Wasserstrom, Nicholas A. Morrice, et al.
(2015) Journal of Cell Science, 128 p.472-486
Journal articleRegulation of SERCA2 activity by PDE3A in human myocardium: Phosphorylation-dependent interaction of PDE3A1 with SERCA2.
Faiyaz Ahmad, Weixing Shen, Fabrice Vandeput, Nicolas Szabo-Fresnais, Judith Krall, et al.
(2015) Journal of Biological Chemistry, 290 p.6763-6776
Journal articlePropionic acid and butyric acid inhibit lipolysis and de novo lipogenesis and increase insulin-stimulated glucose uptake in primary rat adipocytes.
Emilia Heimann, Margareta Nyman, Eva Degerman
(2015) Adipocyte, 4 p.81-88
Journal articleSuperantigen activates the gp130 receptor on adipocytes resulting in altered adipocyte metabolism.
Elin Banke, Karin Rödström, Mikael Ekelund, Jonathan Dalla-Riva, Jens Lagerstedt, et al.
(2014) Metabolism, Clinical and Experimental, 63 p.831-840
Journal articleA link between GIP and osteopontin in adipose tissue and insulin resistance.
Emma Ahlqvist, Peter Osmark, Tiina Kuulasmaa, Kasper Pilgaard, Bilal Omar, et al.
(2013) Diabetes, 62 p.2088-2094
Journal articleA Role for Phosphodiesterase 3B in Acquisition of Brown Fat Characteristics by White Adipose Tissue in Male Mice.
Emilia Guirguis, Steven Hockman, Youn Wook Chung, Faiyaz Ahmad, Oksana Gavrilova, et al.
(2013) Endocrinology, 154 p.3152-3167
Journal articleExpression of insulin signalling components in the sensory epithelium of the human saccule.
Eva Degerman, Uwe Rauch, Sven Lindberg, Per Caye-Thomasen, Anna Hultgårdh, et al.
(2013) Cell and Tissue Research, 352 p.469-478
Journal articleCocaine- and amphetamine-regulated transcript is expressed in adipocytes and regulate lipid- and glucose homeostasis.
Elin Banke, Matteo Riva, Liliya Shcherbina, Nils Wierup, Eva Degerman
(2013) Regulatory Peptides, 182 p.35-40
Journal articleRegulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes - A role for the transcription factor NFAT and phosphodiesterase 3B.
Bilal Omar, Elin Banke, Emilia Guiguis, Lina Kesson, Vincent Manganiello, et al.
(2012) Biochemical and Biophysical Research Communications, 425 p.812-817
Journal articleCyclic Nucleotide Phosphodiesterase 3 Signaling Complexes
F. Ahmad, Eva Degerman, V. C. Manganiello
(2012) Hormone and Metabolic Research, 44 p.776-785
Journal article reviewReduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.
Sofia A Andersson, Anders H Olsson, Jonathan L S Esguerra, Emilia Heimann, Claes Ladenvall, et al.
(2012) Molecular and Cellular Endocrinology, 364 p.36-45
Journal articleRole of phosphodiesterases in the shaping of sub-plasma-membrane cAMP oscillations and pulsatile insulin secretion
Geng Tian, Jenny Sagetorp, Yunjian Xu, Hongyan Shuai, Eva Degerman, et al.
(2012) Journal of Cell Science, 125 p.5084-5095
Journal articleIdentification of new signaling components in the sensory epithelium of human saccule.
Eva Degerman, Uwe Rauch, Olga Göransson, Sven Lindberg, Anna Hultgårdh, et al.
(2011) Frontiers in Neurology, 2
Journal articleInsulin Reduces Neuronal Excitability by Turning on GABA(A) Channels that Generate Tonic Current
Zhe Jin, Yang Jin, Suresh Kumar-Mendu, Eva Degerman, Leif Groop, et al.
(2011) PLoS ONE, 6
Journal articleRye bran alkylresorcinols suppress adipocyte lipolysis and hormone-sensitive lipase activity
Ulrika Axling, Estera Dey, Cecilia Holm, Eva Degerman
(2011) Molecular Nutrition and Food Research, 55 p.290-293
Journal articleFrom PDE3B to the regulation of energy homeostasis.
Eva Degerman, Faiyaz Ahmad, Youn Wook Chung, Emilia Guirguis, Bilal Omar, et al.
(2011) Current Opinion in Pharmacology, 11 p.676-682
Journal articleSalicylamide and salicylglycine oxidovanadium complexes with insulin-mimetic properties.
Jessica Nilsson, Albert A Shteinman, Eva Degerman, Eva A Enyedy, Tamás Kiss, et al.
(2011) Journal of Inorganic Biochemistry, 105 p.1795-1800
Journal articleAlterations in Cyclic Nucleotide Phosphodiesterase Activities in Omental and Subcutaneous Adipose Tissues in Human Obesity
Bilal Omar, Elin Banke, Mikael Ekelund, Frederiksen SG, Eva Degerman
(2011) Nutrition and Diabetes, 1 p.13-13
Journal articleExpression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets.
Emilia Heimann, Helena Jones, Svante Resjö, Vincent C Manganiello, Lena Stenson, et al.
(2010) PLoS ONE, 5
Journal articleDifferential regulation of adipocyte PDE3B in distinct membrane compartments by insulin and the beta(3)-adrenergic receptor agonist CL316243: effects of caveolin-1 knockdown on formation/maintenance of macromolecular signalling complexes
Faiyaz Ahmad, Rebecka Lindh, Yan Tang, Iida Ruishalme, Anita Ost, et al.
(2009) Biochemical Journal, 424 p.399-410
Journal articleRegulation of AMP-activated protein kinase by cAMP in adipocytes: Roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis.
Bilal Omar, Emilia Zmuda-Trzebiatowska, Vincent Manganiello, Olga Göransson, Eva Degerman
(2009) Cellular Signalling, 21 p.760-766
Journal articleProtein kinase B activity is required for the effects of insulin on lipid metabolism in adipocytes.
Christine Berggreen, Amelie Gormand, Bilal Omar, Eva Degerman, Olga Göransson
(2009) American Journal of Physiology: Endocrinology and Metabolism, 296 p.635-646
Journal articlePhosphodiesterase 3B is localized in caveolae and smooth ER in mouse hepatocytes and is important in the regulation of glucose and lipid metabolism.
Karin Berger, Rebecka Lindh, Nils Wierup, Emilia Zmuda-Trzebiatowska, Andreas Lindqvist, et al.
(2009) PLoS ONE, 4
Journal articleCell-cell communication between adipocytes and pancreatic beta-cells in acoustically levitated droplets
Sabina Santesson, Eva Degerman, Patrik Rorsman, Thomas Johansson, Sandra Lemos, et al.
(2009) Integrative Biology, 1 p.595-601
Journal articleBis- and tris(pyridyl)amine-oxidovanadium complexes: characteristics and insulin-mimetic potential.
Jessica Nilsson, Eva Degerman, Matti Haukka, George C Lisensky, Eugenio Garribba, et al.
(2009) Dalton Transactions , p.7902-7911
Journal articleMacroporous gel particles as robust macroporous matrices for cell immobilization
Fatima Plieva, A Oknianska, Eva Degerman, Bo Mattiasson
(2008) Biotechnology Journal, 3 p.410-417
Journal articleInsulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB
Faiyaz Ahmad, Rebecka Lindh, Yan Tang, Marie Weston, Eva Degerman, et al.
(2007) Biochemical Journal, 404 p.257-268
Journal articlebeta-cell PDE3B regulates Ca(2+)-stimulated exocytosis of insulin.
Helena Jones, Nils Wierup, Jenny Vikman, Vincent C Manganiello, Eva Degerman, et al.
(2007) Cellular Signalling, 19 p.1505-1513
Journal articleMultisite phosphorylation of adipocyte and hepatocyte phosphodiesterase 3B.
Rebecka Lindh, Faiyaz Ahmad, Svante Resjö, Peter James, Jeong S Yang, et al.
(2007) Biochimica et Biophysica Acta: Molecular Cell Research, 1773 p.584-592
Journal articlePerilipin and adipophilin expression in lipid loaded macrophages
Jenny Persson, Eva Degerman, Jan Nilsson, Marie Lindholm
(2007) Biochemical and Biophysical Research Communications, 363 p.1020-1026
Journal articleLong-term regulation of cyclic nucleotide phosphodiesterase type 3B and 4 in 3T3-L1 adipocytes.
Alina Oknianska, Emilia Zmuda-Trzebiatowska, Vincent Manganiello, Eva Degerman
(2007) Biochemical and Biophysical Research Communications, 353 p.1080-1085
Journal articleRegulation of cyclic nucleotide phosphodiesterase 3 (PDE3)
VC Manganiello, F Ahmad, YH Choi, Y Tang, R Lindh, et al.
(2007)
BookRe-discovering PDE3 inhibitors - New opportunities for a long neglected target
Philip E. Thompson, Vincent Manganiello, Eva Degerman
(2007) Current Topics in Medicinal Chemistry, 7 p.421-436
Journal article reviewNovel mechanisms of the regulation of Protein kinase B in adipocytes; implications for Protein kinase A, Epac, Phosphodiesterases 3 and 4.
Emilia Zmuda-Trzebiatowska, Vincent Manganiello, Eva Degerman
(2007) Cellular Signalling, 19 p.81-86
Journal articleNovel supermacroporous dextran gels
Fatima Plieva, Alina Oknianska, Eva Degerman, Igor Galaev, Bo Mattiasson
(2006) Journal of Biomaterials Science. Polymer Edition, 17 p.1075-1092
Journal articleEarly and rapid development of insulin resistance, islet dysfunction and glucose intolerance after high-fat feeding in mice overexpressing phosphodiesterase 3B.
Helena Jones, Linda Härndahl, Nils Wierup, Emilia Zmuda-Trzebiatowska, Fredrik Svennelid, et al.
(2006) Journal of Endocrinology, 189 p.629-641
Journal articleAlterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice
Young Hun Choi, Sunhee Park, Steven Hockman, Emilia Zmuda-Trzebiatowska, Fredrik Svennelid, et al.
(2006) Journal of Clinical Investigation, 116 p.3240-3251
Journal articlePlasma membrane cyclic nucleotide phosphodiesterase 3B (PDE3B) is associated with caveolae in primary adipocytes.
Rebecka Nilsson, Faiyaz Ahmad, Karl Swärd, Ulrika Axling, Marie Weston, et al.
(2006) Cellular Signalling, 18 p.1713-1721
Journal articleChemical derivatization of phosphoserine and phosphothreonine containing peptides to increase sensitivity for MALDI-based analysis and for selectivity of MS/MS analysis
Giorgio Arrigoni, Svante Resjö, Fredrik Levander, R Nilsson, Eva Degerman, et al.
(2006) Proteomics, 6 p.757-766
Journal articleImportance of cAMP-response element-binding protein in regulation of expression of the murine cyclic nucleotide phosphodiesterase 3B (Pde3b) gene in differentiating 3T3-L1 preadipocytes
Hanguan Liu, Jing Rong Tang, Young Hun Choi, Maria Napolitano, Steven Hockman, et al.
(2006) Journal of Biological Chemistry, 281 p.21096-21113
Journal articleRole of PDE3B in insulin-induced glucose uptake, GLUT-4 translocation and lipogenesis in primary rat adipocytes.
Emilia Zmuda-Trzebiatowska, Alina Oknianska, Vincent Manganiello, Eva Degerman
(2006) Cellular Signalling, 18 p.382-390
Journal articleIdentification of promoter elements in 5'-flanking region of murine cyclic nucleotide phosphodiesterase 3B gene
Hanguan Liu, Jing Rong Tang, Eva Degerman, Vincent C Manganiello
(2005) Phosphodiesterase Methods and Protocols (Methods in molecular biology), 307 p.109-124
Book chapterDimethylaminopurine inhibits metabolic effects of insulin in primary adipocytes.
Olga Göransson, Mikael Rydén, Rebecka Nilsson, Peter Arner, Eva Degerman
(2004) Journal of Nutritional Biochemistry, 15 p.303-312
Journal articleBeta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance and deranged glucose morphology.
Linda Härndahl, Nils Wierup, Sven Enerbäck, Hindrik Mulder, Vincent C Manganiello, et al.
(2004) Journal of Biological Chemistry, 279 p.15214-15222
Journal articleDual Effects of Pituitary Adenylate Cyclase-Activating Polypeptide and Isoproterenol on Lipid Metabolism and Signaling in Primary Rat Adipocytes.
Lina Åkesson, Bo Ahrén, Vincent C. Manganiello, Lena Stenson, Gudrun Edgren, et al.
(2003) Endocrinology, 144 p.5293-5299
Journal articleImportant role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta -cell exocytosis and release of insulin.
Linda Härndahl, Xingjun Jing, Rosita Ivarsson, Eva Degerman, Bo Ahrén, et al.
(2002) Journal of Biological Chemistry, 277 p.37446-37455
Journal articleC(2)-ceramide influences the expression and insulin-mediated regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 adipocytes.
Jie Mei, Lena Stenson, Tova Landström, Cecilia Holm, David Brindley, et al.
(2002) Diabetes, 51 p.631-637
Journal articleSer-474 is the major target of insulin-mediated phosphorylation of protein kinase B beta in primary rat adipocytes.
Olga Göransson, Svante Resjö, Lars Rönnstrand, Vincent Manganiello, Eva Degerman
(2002) Cellular Signalling, 14 p.175-182
Journal articleProtein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes.
Svante Resjö, Olga Göransson, Linda Härndahl, Stanislaw Zolnierowicz, Vincent Manganiello, et al.
(2002) Cellular Signalling, 14 p.231-238
Journal articleAirborne Single Cell Chemistry
Sabina Santesson, Peter Viberg, T Johansson, Johan Nilsson, Thomas Laurell, et al.
(2002) European Biotechnology News, 1 p.39-40
Journal articleMethods to study phosphorylation and activation of the hormone-sensitive adipocyte phosphodiesterase type 3B in rat adipocytes
Eva Degerman, Svante Resjö, Tova Landström, Vincent Manganiello
(2001) Methods in Molecular Biology, 155 p.167-180
Journal articleHuman impact on the fish diversity in the four largest lakes of Sweden
Eva Degerman, Johan Hammar, Per Nyberg, Gunnar Svardson
(2001) Ambio: a Journal of Human Environment, 30 p.522-528
Journal articleIdentification of a novel isoform of the cyclic-nucleotide phosphodiesterase PDE3A expressed in vascular smooth-muscle myocytes
Young-Hun Choi, Dag Ekholm, Judith Krall, Faiyaz Ahmad, Eva Degerman, et al.
(2001) Biochemical Journal, 353 p.41-50
Journal articleRegulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family
Yasmin Shakur, Lena Stenson Holst, Tova Rahn Landstrom, Matthew Movsesian, Eva Degerman, et al.
(2001) Progress in Molecular Biology and Translational Science, 66 p.241-277
Journal articleFunctions of the N-terminal region of cyclic nucleotide phosphodiesterase 3 (PDE 3) isoforms
Y Kenan, T Murata, Y Shakur, Eva Degerman, V C Manganiello
(2000) Journal of Biological Chemistry, 275 p.12331-12338
Journal articleAirborne cell analysis
Sabina Santesson, Martin Andersson, Eva Degerman, Thomas Johansson, Johan Nilsson, et al.
(2000) Analytical Chemistry, 72 p.3412-3418
Journal articleSubstrates of semicarbazide-sensitive amine oxidase co-operate with vanadate to stimulate tyrosine phosphorylation of insulin-receptor-substrate proteins, phosphoinositide 3-kinase activity and GLUT4 translocation in adipose cells
G Enrique-Tarancon, I Castan, N Morin, L Marti, A Abella, et al.
(2000) Biochemical Journal, 350 p.171-180
Journal articleDown-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumour necrosis factor alpha and cAMP
Tova Landström, Jie Mei, Marie Karlsson, V Manganiello, Eva Degerman
(2000) Biochemical Journal, 346 p.337-343
Journal articleCyclic nucleotide phosphodiesterase 3B is a downstream target of protein kinase B and may be involved in regulation of effects of protein kinase B on thymidine incorporation in FDCP2 cells
F Ahmad, L N Cong, Lena Stenson, L M Wang, Tova Landström, et al.
(2000) Journal of Immunology, 164 p.4678-4688
Journal articleMembrane localization of cyclic nucleotide phosphodiesterase 3 (PDE3). Two N-terminal domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum
Y Shakur, K Takeda, Y Kenan, Z X Yu, G Rena, et al.
(2000) Journal of Biological Chemistry, 275 p.38749-38761
Journal articlePhosphorylation of PDE3B by phosphatidylinositol 3-kinase associated with the insulin receptor
C M Rondinone, E Carvalho, T Rahn, V C Manganiello, Eva Degerman, et al.
(2000) Journal of Biological Chemistry, 275 p.10093-10098
Journal articleMechanisms involved in the regulation of free fatty acid release from isolated human fat cells by acylation-stimulating protein and insulin
V Van Harmelen, S Reynisdottir, K Cianflone, Eva Degerman, J Hoffstedt, et al.
(1999) Journal of Biological Chemistry, 274 p.18243-18251
Journal articleCyclic nucleotide phosphodiesterases (PDE) 3 and 4 in normal, malignant, and HTLV-I transformed human lymphocytes
Dag Ekholm, J C Mulloy, G Gao, Eva Degerman, G Franchini, et al.
(1999) Biochemical Pharmacology, 58 p.935-950
Journal articleMechanisms of inhibition of lipolysis by insulin, vanadate and peroxovanadate in rat adipocytes
Isabelle Castan, Jonny Wijkander, V Manganiello, Eva Degerman
(1999) Biochemical Journal, 339 p.281-289
Journal articlePhosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A
Svante Resjö, A Oknianska, S Zolnierowicz, V Manganiello, Eva Degerman
(1999) Biochemical Journal, 341 p.245-839
Journal articleIL-3 and IL-4 activate cyclic nucleotide phosphodiesterases 3 (PDE3) and 4 (PDE4) by different mechanisms in FDCP2 myeloid cells
F Ahmad, G Gao, L M Wang, Tova Landström, Eva Degerman, et al.
(1999) Journal of Immunology, 162 p.4864-4875
Journal articleCyclic nucleotide phosphodiesterases (PDEs): diverse regulators of cyclic nucleotide signals and inviting molecular targets for novel therapeutic agents
V C Manganiello, Eva Degerman
(1999) Thrombosis and Haemostasis, 82 p.407-411
Journal articleHormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells
Hindrik Mulder, Lena Stensson Holst, Håkan Svensson, Eva Degerman, Frank Sundler, et al.
(1999) Diabetes, 48 p.228-232
Journal articlePhosphorylation and activation of hormone-sensitive adipocyte phosphodiesterase type 3B
Eva Degerman, Tova Landström, Jonny Wijkander, Lena Stenson, F Ahmad, et al.
(1998) Methods, 14 p.43-53
Journal articleIdentification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro
M W Anthonsen, Lars Rönnstrand, C Wernstedt, Eva Degerman, Cecilia Holm
(1998) Journal of Biological Chemistry, 273 p.215-221
Journal articleInsulin-induced phosphorylation and activation of phosphodiesterase 3B in rat adipocytes: possible role for protein kinase B but not mitogen-activated protein kinase or p70 S6 kinase
Jonny Wijkander, Tova Landström, Vincent Manganiello, Per Belfrage, Eva Degerman
(1998) Endocrinology, 139 p.219-227
Journal articleExpression and characterization of deletion recombinants of two cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE-3)
R He, N Komas, Dag Ekholm, T Murata, M Taira, et al.
(1998) Cell Biochemistry and Biophysics, 29 p.89-111
Journal articleInsulin-induced translocation of protein kinase B to the plasma membrane in rat adipocytes
Olga Göransson, Jonny Wijkander, V Manganiello, Eva Degerman
(1998) Biochemical and Biophysical Research Communications, 246 p.249-254
Journal articleProtein kinase B is expressed in pancreatic beta cells and activated upon stimulation with insulin-like growth factor I
Lena Stenson, Hindrik Mulder, V Manganiello, Frank Sundler, Bo Ahrén, et al.
(1998) Biochemical and Biophysical Research Communications, 250 p.181-186
Journal articleVarious phosphodiesterase subtypes mediate the in vivo antilipolytic effect of insulin on adipose tissue and skeletal muscle in man
S Enoksson, Eva Degerman, E Hagstrom-Toft, V Large, P Arner
(1998) Diabetologia, 41 p.560-568
Journal article[2] Regulation of hormone-sensitive lipase activity in adipose tissue
Cecilia Holm, Dominique Langin, Vincent Manganiello, Per Belfrage, Eva Degerman
(1997) Methods in Enzymology, 286 p.45-67
Journal articlePartial purification and identification of hormone-sensitive lipase from chicken adipose tissue
Marit W Anthonsen, Eva Degerman, Cecilia Holm
(1997) Biochemical and Biophysical Research Communications, 236 p.94-99
Journal articleProtein kinase A-dependent activation of PDE4 (cAMP-specific cyclic nucleotide phosphodiesterase) in cultured bovine vascular smooth muscle cells
Dag Ekholm, Per Belfrage, Vincent Manganiello, Eva Degerman
(1997) Biochimica et Biophysica Acta, 1356 p.64-70
Journal articleRegulation of protein kinase B in rat adipocytes by insulin, vanadate, and peroxovanadate. Membrane translocation in response to peroxovanadate
Jonny Wijkander, Lena Stenson, Tova Rahn, Svante Resjö, Isabelle Castan, et al.
(1997) Journal of Biological Chemistry, 272 p.21520-21526
Journal articleStructure, localization, and regulation of cGMP-inhibited phosphodiesterase (PDE3)
Eva Degerman, Per Belfrage, Vincent C Manganiello
(1997) Journal of Biological Chemistry, 272 p.6823-6826
Journal article reviewDomain-structure analysis of recombinant rat hormone-sensitive lipase
Torben Österlund, Birgitta Danielsson, Eva Degerman, Juan Antonio Contreras, Gudrun Edgren, et al.
(1996) Biochemical Journal, 319 p.411-420
Journal articlecGMP-inhibited phosphodiesterases (PDE3 gene family)
Eva Degerman, P Belfrage, V C Manganiello
(1996) Biochemical Society Transactions, 24 p.1010-1014
Journal articleType III cyclic nucleotide phosphodiesterases and insulin action
V C Manganiello, Eva Degerman, M Taira, T Kono, P Belfrage
(1996) Current topics in cellular regulation, 34 p.63-100
Journal articleCharacterization of two recombinant PDE3 (cGMP-inhibited cyclic nucleotide phosphodiesterase) isoforms, RcGIP1 and HcGIP2, expressed in NIH 3006 murine fibroblasts and Sf9 insect cells
Marie-Josephe Leroy, Eva Degerman, Masato Taira, Taku Murata, Lu Hua Wang, et al.
(1996) Biochemistry, 35 p.10194-10202
Journal articleIdentification of the site in the cGMP-inhibited phosphodiesterase phosphorylated in adipocytes in response to insulin and isoproterenol
Tova Rahn, Lars Rönnstrand, Marie-Josephe Leroy, Christer Wernstedt, Hans Tornqvist, et al.
(1996) Journal of Biological Chemistry, 271 p.11575-11580
Journal articleGrowth hormone stimulates the tyrosine phosphorylation of the insulin receptor substrate-1 and its association with phosphatidylinositol 3-kinase in primary adipocytes
Martin Ridderstrale, Eva Degerman, Hans Törnqvist
(1995) Journal of Biological Chemistry, 270 p.3471-3474
Journal articleThe acute insulin-like effects of growth hormone in primary adipocyte-signaling mechanisms
Hans Törnqvist, Martin Ridderstråle, Hans Eriksson, Eva Degerman
(1995) Annals of the New York Academy of Sciences, 766 p.469-471
Journal articleEvidence for the key role of the adipocyte cGMP-inhibited cAMP phosphodiesterase in the antilipolytic action of insulin
Hans Eriksson, Martin Ridderstråle, Eva Degerman, Dag Ekholm, Carolyn J Smith, et al.
(1995) Biochimica et Biophysica Acta, 1266 p.101-107
Journal articleDiversity in cyclic nucleotide phosphodiesterase isoenzyme families
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