Erik Renström
Publications
Retrieved from Lund University's publications database
Latest
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Publications
- 2018
- Intestinal CART is a regulator of GIP and GLP-1 secretion and expression
(2018) Elsevier
Journal article
- Intestinal CART is a regulator of GIP and GLP-1 secretion and expression
- 2017
- Loss of a2d-1 calcium channel subunit function increases the susceptibility for diabetes
(2017) American Diabetes Association Inc.
Journal article - Palmitoylation of Ca2+ channel subunit CaVβ2a induces pancreatic beta-cell toxicity via Ca2+ overload
(2017) Elsevier
Journal article - Regulation of Nuclear Receptor Interacting Protein 1 (NRIP1) Gene Expression in Response to Weight Loss and Exercise in Humans
(2017) Nature Publishing Group
Journal article - The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
(2017) Springer Verlag
Journal article
- Loss of a2d-1 calcium channel subunit function increases the susceptibility for diabetes
- 2016
- C4b-binding protein protects β-cells from islet amyloid polypeptide-induced cytotoxicity
(2016) ASBMB
Journal article - CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion
(2016) Springer Verlag
Journal article - Elevated basal insulin secretion in type 2 diabetes caused by reduced plasma membrane cholesterol
(2016) The Endocrine Society
Journal article - HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets.
(2016) Elsevier
Journal article - MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes.
(2016) Cell Press
Journal article
- C4b-binding protein protects β-cells from islet amyloid polypeptide-induced cytotoxicity
- 2015
- Complement inhibitor CD55 governs the integrity of membrane rafts in pancreatic beta cells, but plays no role in insulin secretion.
(2015) Elsevier
Journal article - Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice with Severe Acute Pancreatitis.
(2015) W B Saunders
Journal article
- Complement inhibitor CD55 governs the integrity of membrane rafts in pancreatic beta cells, but plays no role in insulin secretion.
- 2014
- Dynamic Magnetic Fields Remote-Control Apoptosis via Nanoparticle Rotation.
(2014) The American Chemical Society
Journal article - Genotype-based treatment of type 2 diabetes with an α2A-adrenergic receptor antagonist.
(2014) American Association for the Advancement of Science (AAAS)
Journal article - Glioma Cell Proliferation Controlled by ERK Activity-Dependent Surface Expression of PDGFRA.
(2014) Public Library of Science
Journal article - Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
(2014) National Acad Sciences
Journal article - TCF7L2 is a master regulator of insulin production and processing.
(2014) Oxford University Press
Journal article - The Complement Inhibitor CD59 Regulates Insulin Secretion by Modulating Exocytotic Events.
(2014) Cell Press
Journal article
- Dynamic Magnetic Fields Remote-Control Apoptosis via Nanoparticle Rotation.
- 2013
- Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.
(2013) American Diabetes Association Inc.
Journal article - Eukaryotic translation initiation factor 3 subunit e controls intracellular calcium homeostasis by regulation of cav1.2 surface expression.
(2013) Public Library of Science
Journal article - Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes.
(2013) Elsevier
Journal article - The human L-type calcium channel Ca(v)1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes.
(2013) Springer Verlag
Journal article
- Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.
- 2012
- A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
(2012) Cell Press
Journal article - Impact of transcription factor 7-like 2 (TCF7L2) on pancreatic islet function and morphology in mice and men.
(2012) Springer Verlag
Journal article - Increased DNA Methylation and Decreased Expression of PDX-1 in Pancreatic Islets from Patients with Type 2 Diabetes.
(2012) The Endocrine Society
Journal article - Islet amyloid polypeptide triggers limited complement activation and binds complement inhibitor C4b-binding protein, which enhances fibril formation.
(2012) ASBMB
Journal article - Reduced Insulin Exocytosis in Human Pancreatic β-cells With Gene Variants Linked to Type 2 Diabetes.
(2012) American Diabetes Association Inc.
Journal article - Role of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes.
(2012) Springer Verlag
Journal article - Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
(2012) Cell Press
Journal article - Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway.
(2012) Oxford University Press
Journal article - The adult human brain harbors multipotent perivascular mesenchymal stem cells.
(2012) Public Library of Science
Journal article - Truncated and Full-Length Thioredoxin-1 Have Opposing Activating and Inhibitory Properties for Human Complement with Relevance to Endothelial Surfaces.
(2012) American Association of Immunologists
Journal article - γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes.
(2012) Springer Verlag
Journal article
- A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
- 2011
- Survival of rat pancreatic islets is partly controlled by a TCF7L2-p53-p53INP1 dependent pathway
(2011) Springer Verlag
Journal article
- Survival of rat pancreatic islets is partly controlled by a TCF7L2-p53-p53INP1 dependent pathway
- 2010
- ClC-3-A Granular Anion Transporter Involved in Insulin Secretion? Response
(2010) Cell Press
Journal article (letter) - Complement inhibitor C4b-binding protein (C4BP) binding to islet amyloid polypeptide prevents complement activation and further fibril formation in the endocrine pancreas
(2010) Pergamon
Conference paper: abstract - Complement receptor C5aR is expressed in pancreatic islets and affects glucose-induced insulin and glucagon secretion
(2010) Springer Verlag
Conference paper: abstract - Enhancement of glucagon secretion in mouse and human pancreatic alpha cells by protein kinase C (PKC) involves intracellular trafficking of PKCalpha and PKCdelta.
(2010) Springer Verlag
Journal article - GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis.
(2010) Cell Press
Journal article - Molecular Function of TCF7L2: Consequences of TCF7L2 Splicing for Molecular Function and Risk for Type 2 Diabetes.
(2010) Current Science inc.
Journal article - Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes.
(2010) The American Association for the Advancement of Science
Journal article - Polymorphisms in CACNA1D affect insulin release and channel expression and associate with type 2 diabetes
(2010) Springer Verlag
Conference paper: abstract - TCF7L2-conferred apoptosis in pancreatic beta cells involves the p53 pathway
(2010) Springer Verlag
Conference paper: abstract - The interactions of thioredoxin and the complement system
(2010) Pergamon
Conference paper: abstract - The role of wnt antagonists in impaired beta cell exocytosis
(2010) Springer Verlag
Conference paper: abstract
- ClC-3-A Granular Anion Transporter Involved in Insulin Secretion? Response
- 2009
- Autologous hematopoietic stem cell transplantation in type 1-diabetes.
(2009) Landes Bioscience
Journal article - Bone marrow transplantation stimulates pancreatic β-cell replication after tissue damage.
(2009) Landes Bioscience
Journal article - Complement factors are expressed in pancreatic islets and affect glucose induced insulin secretion
(2009) Springer Verlag
Conference paper: abstract - Evaluation of chloride channel-3 as a potential target for TCF7L2-dependent impairment of insulin secretion
(2009) Springer Verlag
Conference paper: abstract - Glutaredoxin-1 mediates NADPH-dependent stimulation of calcium-dependent insulin secretion.
(2009) The Endocrine Society
Journal article - Hyperactivity in adrenergic signalling via alpha2A receptors contributes to human type 2 diabetes
(2009) Springer Verlag
Conference paper: abstract - Rapid changes in surface expression of L-type Cav1.2 channels in stimulated INS-1 cells
(2009) Springer Verlag
Conference paper: abstract - Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3.
(2009) Cell Press
Journal article - The impact of differential splicing of TCF7L2 on target gene expression in human islet of Langerhans
(2009) Springer Verlag
Conference paper: abstract - Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.
(2009) Springer Verlag
Journal article
- Autologous hematopoietic stem cell transplantation in type 1-diabetes.
- 2008
- CAPS1 and CAPS2 Regulate Stability and Recruitment of Insulin Granules in Mouse Pancreatic beta Cells.
(2008) Cell Press
Journal article - NADPH as a putative regulator of voltage-gated Ca2+ channels in pancreatic beta cells
(2008) Springer Verlag
Conference paper: abstract - Why treatment fails in type 2 diabetes.
(2008) Public Library of Science
Journal article
- CAPS1 and CAPS2 Regulate Stability and Recruitment of Insulin Granules in Mouse Pancreatic beta Cells.
- 2007
- Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion
(2007) Springer Verlag
Journal article - R-type Ca2+-channel-evoked CICR regulates glucose-induced somatostatin secretion
(2007) Nature Publishing Group
Journal article
- Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion
- 2006
- Anaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets.
(2006) Springer Verlag
Journal article - Failure of Transplanted Bone Marrow Cells to Adopt a Pancreatic {beta}-Cell Fate.
(2006) American Diabetes Association Inc.
Journal article - Separately inherited defects in insulin exocytosis and beta-cell glucose metabolism contribute to type 2 diabetes.
(2006) American Diabetes Association Inc.
Journal article - Tomosyn-1 is involved in a post-docking event required for pancreatic beta-cell exocytosis
(2006) The Company of Biologists Ltd
Journal article
- Anaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets.
- 2005
- CaV2.3 calcium channels control second-phase insulin release.
(2005) The Journal of Clinical Investigation
Journal article - Myosin 5a controls insulin granule recruitment during late-phase secretion.
(2005) Wiley-Blackwell
Journal article - Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin
(2005) American Diabetes Association Inc.
Journal article - The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient {beta}-cell mass and exocytosis.
(2005) Oxford University Press
Journal article - The ablation of the Ca(v)2.3/E-type voltage-gated Ca2+ channel causes a mild phenotype despite an altered glucose induced glucagon response in isolated islets of Langerhans
(2005) Elsevier
Journal article
- CaV2.3 calcium channels control second-phase insulin release.
- 2004
- Enhanced cAMP/Protein Kinase A signaling determines improved insulin secretion in a clonal insulin-producing {beta}-cell line (INS-1 832/13).
(2004) The Endocrine Society
Journal article - Isoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca2+ channels
(2004) The Journal of Clinical Investigation
Journal article - Large dense-core vesicle exocytosis in pancreatic beta-cells monitored by capacitance measurements
(2004) Elsevier
Journal article - Temperature-Sensitive Random Insulin Granule Diffusion is a Prerequisite for Recruiting Granules for Release.
(2004) Wiley-Blackwell
Journal article
- Enhanced cAMP/Protein Kinase A signaling determines improved insulin secretion in a clonal insulin-producing {beta}-cell line (INS-1 832/13).
- 2003
- Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(V)1.2 Ca(2+) channel null mice.
(2003) Oxford University Press
Journal article - Insulin granule dynamics in pancreatic beta cells
(2003) Springer Verlag
Journal article review - SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells.
(2003) Rockefeller Institute for Medical Research
Journal article
- Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(V)1.2 Ca(2+) channel null mice.
- 2002
- A Subset of 50 Secretory Granules in Close Contact With L-Type Ca(2+) Channels Accounts for First-Phase Insulin Secretion in Mouse beta-Cells.
(2002) American Diabetes Association Inc.
Journal article - Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells.
(2002) Cell Press
Journal article - Glucose dependence of insulinotropic actions of pituitary adenylate cyclase-activating polypeptide in insulin-secreting INS-1 cells.
(2002) Springer
Journal article - Important role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta -cell exocytosis and release of insulin.
(2002) ASBMB
Journal article - Inositol 3,4,5,6-tetrakisphosphate inhibits insulin granule acidification and fusogenic potential.
(2002) ASBMB
Journal article - Sulfonylurea-Mediated Stimulation of Insulin Exocytosis via an ATP-Sensitive K(+) Channel--Independent Action.
(2002) American Diabetes Association Inc.
Journal article
- A Subset of 50 Secretory Granules in Close Contact With L-Type Ca(2+) Channels Accounts for First-Phase Insulin Secretion in Mouse beta-Cells.
- 2001
- Differential glucose responsitivity in insulin-producing cell lines derived from the INS-1 line is associated with altered Ca2+dynamics and Ca2+-evoked exocytosis
(2001) Springer Verlag
Journal article - Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells
(2001) Cell Press
Journal article - Perchlorate stimulates insulin secretion by shifting the gating of L-type Ca2+ currents in mouse pancreatic B-cells towards negative potentials
(2001) Springer
Journal article - Phosphodiesterase 3B is activated by glucose and insulin in rat islets and involved in Ca2+-stimulated exocytosis
(2001) Springer Verlag
Journal article - Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification
(2001) The Company of Biologists Ltd
Journal article
- Differential glucose responsitivity in insulin-producing cell lines derived from the INS-1 line is associated with altered Ca2+dynamics and Ca2+-evoked exocytosis
- 2000
- The Cell Physiology of Biphasic Insulin Secretion
(2000) American Physiological Society
Journal article
- The Cell Physiology of Biphasic Insulin Secretion
- 1999
- Activation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells
(1999) Rockefeller Institute for Medical Research
Journal article - CaM kinase II-dependent mobilization of secretory granules underlies acetylcholine-induced stimulation of exocytosis in mouse pancreatic B-cells
(1999) The Physiological Society
Journal article - Cell biology. Glutamate primes the pump
(1999) Nature Publishing Group
Journal article - The stimulatory action of tolbutamide on Ca2+-dependent exocytosis in pancreatic beta cells is mediated by a 65-kDa mdr-like P-glycoprotein
(1999) National Acad Sciences
Journal article - The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery
(1999) National Acad Sciences
Journal article
- Activation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells
- 1997
- Adrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels
(1997) Rockefeller Institute for Medical Research
Journal article - Components of insulin secretion: lessons to be learnt from capacitance
(1997) Springer
Journal article - Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism
(1997) American Diabetes Association Inc.
Journal article - Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors
(1997) Springer
Journal article - Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells
(1997) The Physiological Society
Journal article - Rapid ATP-dependent priming of secretory granules precedes Ca(2+)-induced exocytosis in mouse pancreatic B-cells
(1997) The Physiological Society
Journal article
- Adrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels
- 1996
- Cooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization
(1996) The Physiological Society
Journal article - Dynamics of the cationic, bioelectrical and secretory responses to formycin A in pancreatic islet cells
(1996) Springer
Journal article - Neurotransmitter-induced inhibition of exocytosis in insulin-secreting beta cells by activation of calcineurin
(1996) Cell Press
Journal article - PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells
(1996) The American Association for the Advancement of Science
Journal article
- Cooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization
- 1995
- Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells
(1995) Oxford University Press
Journal article - Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization
(1995) American Diabetes Association Inc.
Journal article
- Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells
- 1994
- Ion channels, electrical activity and insulin secretion
(1994) Masson Editeur
Journal article
- Ion channels, electrical activity and insulin secretion
12 October 2016
E-mail: erik [dot] renstrom [at] med [dot] lu [dot] se
Adjunct professor
