Erik Renström
Vice-chancellor
Publications
Displaying of publications. Sorted by year, then title.
MAFA and MAFB regulate exocytosis-related genes in human β-cells
Rodrigo Cataldo, Tania Singh, Kavya Achanta, Sara Bsharat, Rashmi B Prasad, et al.
(2022) Acta Physiologica, 234
Journal articleThe Calcium Channel Subunit Gamma-4 as a Novel Regulator of MafA in Pancreatic Beta-Cell Controls Glucose Homeostasis
Rui Wu, Alexandros Karagiannopoulos, Lena Eliasson, Erik Renström, Cheng Luan, et al.
(2022) Biomedicines, 10
Journal articleEpigenome-Wide Histone Acetylation Changes in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes and Atherosclerotic Disease
Pradeep Bompada, Isabel Goncalves, Chuanyan Wu, Rui Gao, Jiangming Sun, et al.
(2021) Biomedicines, 9
Journal articleThe MafA-target gene PPP1R1A regulates GLP1R-mediated amplification of glucose-stimulated insulin secretion in β-cells
Luis Rodrigo Cataldo, Neelanjan Vishnu, Tania Singh, Ludivine Bertonnier-Brouty, Sara Bsharat, et al.
(2021) Metabolism: Clinical and Experimental
Journal articleTranscriptional analysis of islets of Langerhans from organ donors of different ages
Peter Seiron, Anton Stenwall, Anders Hedin, Louise Granlund, Jonathan Lou S. Esguerra, et al.
(2021) PLoS ONE, 16
Journal articleElevated circulating follistatin associates with an increased risk of type 2 diabetes
Chuanyan Wu, Yan Borné, Rui Gao, Maykel López Rodriguez, William C Roell, et al.
(2021) Nature Communications, 12 p.1-10
Journal articleThe TCF7L2-dependent high-voltage activated calcium channel subunit α2δ-1 controls calcium signaling in rodent pancreatic beta-cells
Ye Yingying, Mohammad Barghouth, Cheng Luan, Abdulla Kazim, Yuedan Zhou, et al.
(2020) Molecular and Cellular Endocrinology, 502 p.1-11
Journal articleA circular RNA generated from an intron of the insulin gene controls insulin secretion
Lisa Stoll, Adriana Rodríguez-Trejo, Claudiane Guay, Flora Brozzi, Mustafa Bilal Bayazit, et al.
(2020) Nature Communications, 11
Journal articleA cryptic non-GPI-anchored cytosolic isoform of CD59 controls insulin exocytosis in pancreatic β-cells by interaction with SNARE proteins
Ewelina Golec, Rebecca Rosberg, Enming Zhang, Erik Renström, Anna M Blom, et al.
(2019) FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33 p.12425-12434
Journal articlePancreatic β-cell mRNA modification as a marker for type 2 diabetes
Erik Renström, Enming Zhang
(2019) Nature Metabolism, 1 p.748-749
Journal article reviewThe calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification
Cheng Luan, Ye Yingying, Tania Singh, Mohammad Barghouth, Lena Eliasson, et al.
(2019) Communications Biology, 2
Journal articlePreserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells
Enming Zhang, Israa Mohammed, Sarheed Mohammed, Cheng Luan, Olof Asplund, et al.
(2019) Cell Metabolism, 29 p.6-77
Journal articleComplement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation
Ben King, Klaudia Kulak, Ulrika Krus, Rebecca Rosberg, Ewelina Golec, et al.
(2019) Cell Metabolism, 29 p.6-210
Journal articleDefective exocytosis and processing of insulin in a cystic fibrosis mouse model
Anna Edlund, Mohammad Barghouth, Michael Huhn, Mia Abels, Jonathan Esguerra, et al.
(2019) Journal of Endocrinology, 241 p.45-57
Journal articleIntracellular cytosolic complement component C3 regulates cytoprotective autophagy in pancreatic beta cells by interaction with ATG16L1
Ben C. King, Erik Renström, Anna M. Blom
(2019) Autophagy, 15 p.919-921
Journal article (comment)MafA expression preserves immune homeostasis in human and mouse islets
Tania Singh, Luis Sarmiento, Cheng Luan, Rashmi B. Prasad, Jenny Johansson, et al.
(2018) Genes, 9
Journal articleIntracellular non-GPI anchored isoform of CD59 is responsible for facilitating of insulin secretion from pancreatic beta-cells
Ewelina Golec, Rebecca Rosberg, Enming Zhang, Eitan Netanyah, Erik Renström, et al.
(2018) , p.155-156
Conference paper: abstractIntestinal CART is a regulator of GIP and GLP-1 secretion and expression
L. Shcherbina, A. Lindqvist, A. H. Thorén Fischer, E. Ahlqvist, E. Zhang, et al.
(2018) Molecular and Cellular Endocrinology, 476 p.8-16
Journal articleRegulation of Nuclear Receptor Interacting Protein 1 (NRIP1) Gene Expression in Response to Weight Loss and Exercise in Humans
Yang De Marinis, Jiangming Sun, Pradeep Bompada, Judit Domènech Omella, Cheng Luan, et al.
(2017) Obesity, 25 p.1400-1409
Journal articlePalmitoylation of Ca2+ channel subunit CaVβ2a induces pancreatic beta-cell toxicity via Ca2+ overload
Abdulla S. Kazim, Petter Storm, Enming Zhang, Erik Renström
(2017) Biochemical and Biophysical Research Communications, 491 p.740-746
Journal articleThe human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
Klaudia Kulak, Gunilla T. Westermark, Nikolina Papac-Milicevic, Erik Renström, Anna M. Blom, et al.
(2017) Diabetologia, 60 p.1522-1533
Journal articleLoss of a2d-1 calcium channel subunit function increases the susceptibility for diabetes
Vincenzo Mastrolia, Sylvia M. Flucher, Gerald J. Obermair, Mathias Drach, Helene Hofer, et al.
(2017) Diabetes, 66 p.897-907
Journal articleA cryptic non-GPI anchored form of CD59 facilitates insulin secretion from pancreatic beta cells
Ben C. King, Ewelina Golec, Rebecca Rosberg, Enming Zhang, David O’Connell, et al.
(2017) Molecular Immunology, 89 p.351-351
Conference paper: abstractC4b-binding protein protects β-cells from islet amyloid polypeptide-induced cytotoxicity
Jonatan Sjölander, Elin Byman, Klaudia Kulak, Sara C. Nilsson, Enming Zhang, et al.
(2016) Journal of Biological Chemistry, 291 p.21644-21655
Journal articleElevated basal insulin secretion in type 2 diabetes caused by reduced plasma membrane cholesterol
Vini Nagaraj, Abdulla S. Kazim, Johan Helgeson, Clemens Lewold, Satadal Barik, et al.
(2016) Molecular Endocrinology, 30 p.1059-1069
Journal articleCART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion
Mia Abels, Matteo Riva, Hedvig Bennet, Emma Ahlqvist, Oleg Dyachok, et al.
(2016) Diabetologia, 59 p.1928-1937
Journal articleHMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets.
Yuedan Zhou, Nikolay Oskolkov, Liliya Shcherbina, Joyce Ratti, Kian-Hong Kock, et al.
(2016) Molecular and Cellular Endocrinology, 430 p.138-145
Journal articleMafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes.
Elvira Ganic, Tania Singh, Cheng Luan, Joao Fadista, Jenny Johansson, et al.
(2016) Cell Reports, 14 p.1991-2002
Journal articlePancreatic beta cell dedifferentiation involves the voltage-gated calcium channel subunit gamma4
Cheng Luan, ELVIRA GANIC, Isabella Artner, Enming Zhang, Erik Renström
(2015) Diabetologia, 58 p.208-209
Conference paper: abstractComplement inhibitor CD55 governs the integrity of membrane rafts in pancreatic beta cells, but plays no role in insulin secretion.
Vini Nagaraj, Ben King, Petter Storm, Petter Vikman, Emilia Ottosson Laakso, et al.
(2015) Biochemical and Biophysical Research Communications, 460 p.518-524
Journal articleNeutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice with Severe Acute Pancreatitis.
Mohammed Merza, Hannes Hartman Magnusson, Milladur Rahman, Rundk Hwaiz, Enming Zhang, et al.
(2015) Gastroenterology, 149 p.1920-1920
Journal articleGlioma Cell Proliferation Controlled by ERK Activity-Dependent Surface Expression of PDGFRA.
Dongfeng Chen, Duo Zuo, Cheng Luan, Liu Min, Manli Na, et al.
(2014) PLoS ONE, 9
Journal articleGenotype-based treatment of type 2 diabetes with an α2A-adrenergic receptor antagonist.
Yunzhao Tang, Annika Axelsson, Peter Spégel, Lotta Andersson, Hindrik Mulder, et al.
(2014) Science Translational Medicine, 6 p.139-257
Journal articleTCF7L2 is a master regulator of insulin production and processing.
Yuedan Zhou, Soo-Young Park, Jing Su, Kathleen Bailey, Emilia Ottosson Laakso, et al.
(2014) Human Molecular Genetics, 23 p.6419-6431
Journal articleGlobal genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
Joao Fadista, Petter Vikman, Emilia Ottosson Laakso, Ines Mollet, Jonathan Esguerra, et al.
(2014) Proceedings of the National Academy of Sciences, 111 p.13924-13929
Journal articleThe Complement Inhibitor CD59 Regulates Insulin Secretion by Modulating Exocytotic Events.
Ulrika Krus, Ben King, Vini Nagaraj, Nikhil R Gandasi, Jonatan Sjölander, et al.
(2014) Cell Metabolism, 19 p.883-890
Journal articleDynamic Magnetic Fields Remote-Control Apoptosis via Nanoparticle Rotation.
Enming Zhang, Moritz F Kircher, Martin Koch, Lena Eliasson, S Nahum Goldberg, et al.
(2014) ACS Nano, 8 p.3192-3201
Journal articleEukaryotic translation initiation factor 3 subunit e controls intracellular calcium homeostasis by regulation of cav1.2 surface expression.
Pawel Buda, Thomas Reinbothe, Vini Nagaraj, Taman Mahdi, Cheng Luan, et al.
(2013) PLoS ONE, 8
Journal articleExpression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes.
Jalal Taneera, Joao Fadista, Emma Ahlqvist, Mengze Zhang, Nils Wierup, et al.
(2013) Molecular and Cellular Endocrinology, 375 p.35-42
Journal articleEffect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.
Anna Jonsson, Claes Ladenvall, Tarunveer Singh Ahluwalia, Jasmina Kravic, Ulrika Krus, et al.
(2013) Diabetes, 62 p.2978-2983
Journal articleThe human L-type calcium channel Ca(v)1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes.
Thomas Reinbothe, Sami Alkayyali, Emma Ahlqvist, Tiinamaija Tuomi, Bo Isomaa, et al.
(2013) Diabetologia, 56 p.340-349
Journal articleThe adult human brain harbors multipotent perivascular mesenchymal stem cells.
Gesine Paul-Visse, Ilknur Ozen, Nicolaj Christophersen, Thomas Reinbothe, Johan Bengzon, et al.
(2012) PLoS ONE, 7
Journal articleIncreased DNA Methylation and Decreased Expression of PDX-1 in Pancreatic Islets from Patients with Type 2 Diabetes.
Beatrice Yang, Tasnim Dayeh, Petr Volkov, Clare L Kirkpatrick, Siri Malmgren, et al.
(2012) Molecular Endocrinology, 26 p.1203-1212
Journal articleImpact of transcription factor 7-like 2 (TCF7L2) on pancreatic islet function and morphology in mice and men.
Erik Renström
(2012) Diabetologia, 55 p.2559-2561
Journal articleIslet amyloid polypeptide triggers limited complement activation and binds complement inhibitor C4b-binding protein, which enhances fibril formation.
Jonatan Sjölander, Gunilla T Westermark, Erik Renström, Anna Blom
(2012) Journal of Biological Chemistry, 287 p.10824-10833
Journal articleγ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes.
Jalal Taneera, Z Jin, Yuesheng Jin, Sarheed Jabar Muhammed, Enming Zhang, et al.
(2012) Diabetologia, 55 p.1985-1994
Journal articleSecreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
Taman Mahdi, Sonja Hänzelmann, S Albert Salehi, Sarheed Jabar Muhammed, Thomas Reinbothe, et al.
(2012) Cell Metabolism, 16 p.625-633
Journal articleReduced Insulin Exocytosis in Human Pancreatic β-cells With Gene Variants Linked to Type 2 Diabetes.
Anders Rosengren, Matthias Braun, Taman Mahdi, Sofia A Andersson, Mary E Travers, et al.
(2012) Diabetes, 61 p.1726-1733
Journal articleRole of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes.
George Hindy, Emily Sonestedt, Ulrika Ericson, X-J Jing, Yuedan Zhou, et al.
(2012) Diabetologia, 55 p.2646-2654
Journal articleTruncated and Full-Length Thioredoxin-1 Have Opposing Activating and Inhibitory Properties for Human Complement with Relevance to Endothelial Surfaces.
Ben King, Justyna Nowakowska, Christian M Karsten, Jörg Köhl, Erik Renström, et al.
(2012) Journal of immunology (Baltimore, Md. : 1950), 188 p.4103-4112
Journal articleSurvival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway.
Yuedan Zhou, Enming Zhang, Christine Berggreen, Xingjun Jing, Peter Osmark, et al.
(2012) Human Molecular Genetics, 21 p.196-207
Journal articleA systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
Jalal Taneera, Stefan Lang, Amitabh Sharma, Joao Fadista, Yuedan Zhou, et al.
(2012) Cell Metabolism, 16 p.122-134
Journal articleSurvival of rat pancreatic islets is partly controlled by a TCF7L2-p53-p53INP1 dependent pathway
Y. Zhou, Enming Zhang, C. Berggreen, Xingjun Jing, P. Osmark, et al.
(2011) Diabetologia, 54 p.64-65
Journal articleComplement inhibitor C4b-binding protein (C4BP) binding to islet amyloid polypeptide prevents complement activation and further fibril formation in the endocrine pancreas
Jonatan Sjölander, Gunilla T. Westermark, Erik Renström, Anna Blom
(2010) Molecular Immunology, 47
Conference paper: abstractTCF7L2-conferred apoptosis in pancreatic beta cells involves the p53 pathway
Yuedan Zhou, Enming Zhang, Erik Renström, Leif Groop, Ola Hansson
(2010) Diabetologia, 53 p.298-298
Conference paper: abstractThe role of wnt antagonists in impaired beta cell exocytosis
T Hamed, S Albert Salehi, Erik Renström, Anders Rosengren
(2010) Diabetologia, 53 p.91-91
Conference paper: abstractEnhancement of glucagon secretion in mouse and human pancreatic alpha cells by protein kinase C (PKC) involves intracellular trafficking of PKCalpha and PKCdelta.
Yang De Marinis, Enming Zhang, Stefan Amisten, Jalal Taneera, Erik Renström, et al.
(2010) Diabetologia, 53 p.717-729
Journal articleClC-3-A Granular Anion Transporter Involved in Insulin Secretion? Response
Erik Renström
(2010) Cell Metabolism, 12 p.309-309
Journal article (letter)Complement receptor C5aR is expressed in pancreatic islets and affects glucose-induced insulin and glucagon secretion
Vini Nagaraj, Ulrika Krus, Anna Blom, Erik Renström
(2010) Diabetologia, 53 p.531-531
Conference paper: abstractPolymorphisms in CACNA1D affect insulin release and channel expression and associate with type 2 diabetes
Thomas Reinbothe, Valeriya Lyssenko, Stefan Lang, Erik Renström
(2010) Diabetologia, 53 p.296-296
Conference paper: abstractGLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis.
Yang De Marinis, S Albert Salehi, Caroline E Ward, Quan Zhang, Fernando Abdulkader, et al.
(2010) Cell Metabolism, 11 p.543-553
Journal articleOverexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes.
Anders Rosengren, Ramunas Jokubka, Damon Tojjar, Charlotte Granhall, Ola Hansson, et al.
(2010) Science (New York, N.Y.), 327 p.217-220
Journal articleMolecular Function of TCF7L2: Consequences of TCF7L2 Splicing for Molecular Function and Risk for Type 2 Diabetes.
Ola Hansson, Yuedan Zhou, Erik Renström, Peter Osmark
(2010) Current Diabetes Reports, 10 p.444-451
Journal articleThe interactions of thioredoxin and the complement system
Ben King, Justyna Nowakowska, Erik Renström, Anna Blom
(2010) Molecular Immunology, 47
Conference paper: abstractEvaluation of chloride channel-3 as a potential target for TCF7L2-dependent impairment of insulin secretion
Xingjun Jing, Yuedan Zhou, Peter Osmark, Stefan Lang, Leif Groop, et al.
(2009) Diabetologia, 52 p.332-332
Conference paper: abstractRapid changes in surface expression of L-type Cav1.2 channels in stimulated INS-1 cells
Enming Zhang, Thomas Reinbothe, Sofia A Andersson, Lena Eliasson, M. Brauns, et al.
(2009) Diabetologia, 52 p.436-436
Conference paper: abstractComplement factors are expressed in pancreatic islets and affect glucose induced insulin secretion
Vini Nagaraj, Ulrika Krus, Jonatan Sjölander, Anna Blom, Erik Renström
(2009) Diabetologia, 52 p.455-455
Conference paper: abstractThe impact of differential splicing of TCF7L2 on target gene expression in human islet of Langerhans
Yuedan Zhou, Stefan Lang, Jalal Taneera, Erik Renström, Leif Groop, et al.
(2009) Diabetologia, 52 p.78-78
Conference paper: abstractAutologous hematopoietic stem cell transplantation in type 1-diabetes.
Anders Rosengren, Erik Renström
(2009) Islets, 1 p.81-83
Journal articleBone marrow transplantation stimulates pancreatic β-cell replication after tissue damage.
Anders Rosengren, Jalal Taneera, Simin Rymo, Erik Renström
(2009) Islets, 1 p.10-18
Journal articleSuppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3.
Dai-Qing Li, Xingjun Jing, S Albert Salehi, Stephan C Collins, Michael B Hoppa, et al.
(2009) Cell Metabolism, 10 p.309-315
Journal articleGlutaredoxin-1 mediates NADPH-dependent stimulation of calcium-dependent insulin secretion.
Thomas Reinbothe, Rosita Ivarsson, Dai-Qing Li, Omid Niazi, Xingjun Jing, et al.
(2009) Molecular Endocrinology, 23 p.893-900
Journal articleUnique splicing pattern of the TCF7L2 gene in human pancreatic islets.
Peter Osmark, Ola Hansson, Anna Jonsson, Tina Rönn, Leif Groop, et al.
(2009) Diabetologia, 52 p.850-854
Journal articleHyperactivity in adrenergic signalling via alpha2A receptors contributes to human type 2 diabetes
Anders Rosengren, Ramunas Jokubka, Damon Tojjar, Charlotte Granhall, Jonatan Tuncel, et al.
(2009) Diabetologia, 52 p.108-108
Conference paper: abstractNADPH as a putative regulator of voltage-gated Ca2+ channels in pancreatic beta cells
Thomas Reinbothe, Ulrika Krus, Erik Renström
(2008) Diabetologia, 51 p.196-196
Conference paper: abstractCAPS1 and CAPS2 Regulate Stability and Recruitment of Insulin Granules in Mouse Pancreatic beta Cells.
Dina Speidel, S Albert Salehi, Stefanie Obermueller, Ingmar Lundquist, Nils Brose, et al.
(2008) Cell Metabolism, 7 p.57-67
Journal articleWhy treatment fails in type 2 diabetes.
Anders Rosengren, Xingjun Jing, Lena Eliasson, Erik Renström
(2008) PLoS Medicine, 5 p.1426-1427
Journal articleR-type Ca2+-channel-evoked CICR regulates glucose-induced somatostatin secretion
Quan Zhang, Martin Bengtsson, Chris Partridge, S Albert Salehi, Matthias Braun, et al.
(2007) Nature Cell Biology, 9 p.171-453
Journal articlePolymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion
Johan Holmkvist, Damon Tojjar, Peter Almgren, Valeriya Lyssenko, C M Lindgren, et al.
(2007) Diabetologia, 50 p.2467-2475
Journal articleAnaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets.
Ulrika Krus, Anders Rosengren, F Schuit, Erik Renström, Hindrik Mulder
(2006) Diabetologia, 49 p.1578-1586
Journal articleFailure of Transplanted Bone Marrow Cells to Adopt a Pancreatic {beta}-Cell Fate.
Jalal Taneera, Anders Rosengren, Erik Renström, Jens Nygren, Palle Serup, et al.
(2006) Diabetes, 55 p.290-296
Journal articleSeparately inherited defects in insulin exocytosis and beta-cell glucose metabolism contribute to type 2 diabetes.
Charlotte Granhall, Anders Rosengren, Erik Renström, Holger Luthman
(2006) Diabetes, 55 p.3494-3500
Journal articleTomosyn-1 is involved in a post-docking event required for pancreatic beta-cell exocytosis
Severine Cheviet, Paola Bezzi, Rosita Ivarsson, Erik Renström, David Viertl, et al.
(2006) Journal of Cell Science, 119 p.2912-2920
Journal articleThe ablation of the Ca(v)2.3/E-type voltage-gated Ca2+ channel causes a mild phenotype despite an altered glucose induced glucagon response in isolated islets of Langerhans
A Pereverzev, A Salehi, M Mikhna, Erik Renström, J Hescheler, et al.
(2005) European Journal of Pharmacology, 511 p.65-72
Journal articleThe R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient {beta}-cell mass and exocytosis.
Maria Björkqvist, Malin Fex, Erik Renström, Nils Wierup, Åsa Petersén, et al.
(2005) Human Molecular Genetics, 14 p.565-574
Journal articleMyosin 5a controls insulin granule recruitment during late-phase secretion.
Rosita Ivarsson, Xingjun Jing, Laurent Waselle, Romano Regazzi, Erik Renström
(2005) Traffic: the International Journal of Intracellular Transport, 6 p.1027-1035
Journal articleCaV2.3 calcium channels control second-phase insulin release.
Xingjun Jing, Dai-Qing Li, Charlotta Olofsson, Albert Salehi, Vikas Surve, et al.
(2005) Journal of Clinical Investigation, 115 p.146-154
Journal articleRedox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin
Rosita Ivarsson, R Quintens, S Dejonghe, K Tsukamoto, P Veld, et al.
(2005) Diabetes, 54 p.2132-2142
Journal articleTemperature-Sensitive Random Insulin Granule Diffusion is a Prerequisite for Recruiting Granules for Release.
Rosita Ivarsson, Stefanie Obermüller, Guy A Rutter, Juris Galvanovskis, Erik Renström
(2004) Traffic: the International Journal of Intracellular Transport, 5 p.750-762
Journal articleEnhanced cAMP/Protein Kinase A signaling determines improved insulin secretion in a clonal insulin-producing {beta}-cell line (INS-1 832/13).
Shumin Yang, Ulrika Krus, Lillian Fagerhus, Lena Stenson, Hans E. Hohmeier, et al.
(2004) Molecular Endocrinology, 18 p.2312-2320
Journal articleIsoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca2+ channels
MJ Sinnegger-Brauns, A Hetzenauer, IG Huber, Erik Renström, G Wietzorrek, et al.
(2004) Journal of Clinical Investigation, 113 p.1430-1439
Journal articleLarge dense-core vesicle exocytosis in pancreatic beta-cells monitored by capacitance measurements
T Kanno, Xiaosong Ma, Sebastian Barg, Lena Eliasson, Juris Galvanovskis, et al.
(2004) Methods, 33 p.302-311
Journal articleImpaired insulin secretion and glucose tolerance in beta cell-selective Ca(V)1.2 Ca(2+) channel null mice.
Verena Schulla, Erik Renström, Robert Feil, Susanne Feil, Isobel Franklin, et al.
(2003) EMBO Journal, 22 p.3844-3854
Journal articleSUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells.
Lena Eliasson, Xiaosong Ma, Erik Renström, Sebastian Barg, Per-Olof Berggren, et al.
(2003) Journal of General Physiology, 121 p.181-197
Journal articleInsulin granule dynamics in pancreatic beta cells
Patrik Rorsman, Erik Renström
(2003) Diabetologia, 46 p.1029-1045
Journal article reviewImportant role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta -cell exocytosis and release of insulin.
Linda Härndahl, Xingjun Jing, Rosita Ivarsson, Eva Degerman, Bo Ahrén, et al.
(2002) Journal of Biological Chemistry, 277 p.37446-37455
Journal articleGlucose dependence of insulinotropic actions of pituitary adenylate cyclase-activating polypeptide in insulin-secreting INS-1 cells.
Anders Rosengren, K Filipsson, Xingjun Jing, M K Reimer, Erik Renström
(2002) Pflügers Archiv, 444 p.556-567
Journal articleA Subset of 50 Secretory Granules in Close Contact With L-Type Ca(2+) Channels Accounts for First-Phase Insulin Secretion in Mouse beta-Cells.
Sebastian Barg, Lena Eliasson, Erik Renström, Patrik Rorsman
(2002) Diabetes, 51 Suppl 1 p.74-82
Journal articleSulfonylurea-Mediated Stimulation of Insulin Exocytosis via an ATP-Sensitive K(+) Channel--Independent Action.
Erik Renström, Sebastian Barg, Frank Thévenod, Patrik Rorsman
(2002) Diabetes, 51 p.33-36
Journal articleInositol 3,4,5,6-tetrakisphosphate inhibits insulin granule acidification and fusogenic potential.
Erik Renström, Rosita Ivarsson, Stephen B Shears
(2002) Journal of Biological Chemistry, 277 p.26717-26720
Journal articleDelay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells.
Sebastian Barg, Charlotta Olofsson, Jenny Schriever-Abeln, Anna Wendt, Samuel Gebre-Medhin, et al.
(2002) Neuron, 33 p.287-299
Journal articlePhosphodiesterase 3B is activated by glucose and insulin in rat islets and involved in Ca2+-stimulated exocytosis
Linda Härndahl, Xingjun Jing, Erik Renström, L S Holst
(2001) Diabetologia, 44 p.134-134
Journal articlePriming of insulin granules for exocytosis by granular Cl(-) uptake and acidification
Sebastian Barg, P Huang, Lena Eliasson, D J Nelson, Stefanie Obermüller, et al.
(2001) Journal of Cell Science, 114 p.2145-2154
Journal articleFast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells
Sebastian Barg, Xiaosong Ma, Lena Eliasson, Juris Galvanovskis, Sven Göpel, et al.
(2001) Biophysical Journal, 81 p.3308-3323
Journal articlePerchlorate stimulates insulin secretion by shifting the gating of L-type Ca2+ currents in mouse pancreatic B-cells towards negative potentials
Gerd Larsson-Nyren, Janove Sehlin, Patrik Rorsman, Erik Renström
(2001) Pflügers Archiv, 441 p.587-595
Journal articleDifferential glucose responsitivity in insulin-producing cell lines derived from the INS-1 line is associated with altered Ca2+dynamics and Ca2+-evoked exocytosis
S Yang, Bo Ahrén, Erik Renström, E Hohmeier, C B Newgard, et al.
(2001) Diabetologia, 44 p.134-134
Journal articleThe Cell Physiology of Biphasic Insulin Secretion
Patrik Rorsman, Lena Eliasson, Erik Renström, Jesper Gromada, Sebastian Barg, et al.
(2000) News in Physiological Sciences, 15 p.72-77
Journal articleCaM kinase II-dependent mobilization of secretory granules underlies acetylcholine-induced stimulation of exocytosis in mouse pancreatic B-cells
Jesper Gromada, Marianne Hoy, Erik Renström, Krister Bokvist, Lena Eliasson, et al.
(1999) Journal of Physiology, 518 p.745-759
Journal articleThe stimulatory action of tolbutamide on Ca2+-dependent exocytosis in pancreatic beta cells is mediated by a 65-kDa mdr-like P-glycoprotein
Sebastian Barg, Erik Renström, P O Berggren, A Bertorello, K Bokvist, et al.
(1999) Proceedings of the National Academy of Sciences, 96 p.5539-5544
Journal articleCell biology. Glutamate primes the pump
Patrik Rorsman, Erik Renström
(1999) Nature, 402 p.595-596
Journal articleActivation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells
Sven Göpel, Takahiro Kanno, Sebastian Barg, Lena Eliasson, Juris Galvanovskis, et al.
(1999) Journal of General Physiology, 114 p.759-770
Journal articleThe voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery
O Wiser, M Trus, A Hernandez, Erik Renström, Sebastian Barg, et al.
(1999) Proceedings of the National Academy of Sciences, 96 p.248-253
Journal articleComponents of insulin secretion: lessons to be learnt from capacitance
Patrik Rorsman, Lena Eliasson, Erik Renström
(1997) Japanese Journal of Physiology, 47 p.21-21
Journal articleProtein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells
Erik Renström, Lena Eliasson, Patrik Rorsman
(1997) Journal of Physiology, 502 p.105-118
Journal articleRapid ATP-dependent priming of secretory granules precedes Ca(2+)-induced exocytosis in mouse pancreatic B-cells
Lena Eliasson, Erik Renström, W G Ding, P Proks, Patrik Rorsman
(1997) Journal of Physiology, 503 p.399-412
Journal articleGlucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism
W G Ding, Erik Renström, Patrik Rorsman, K Buschard, J Gromada
(1997) Diabetes, 46 p.792-800
Journal articleMultisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors
J Gromada, W G Ding, Sebastian Barg, Erik Renström, Patrik Rorsman
(1997) Pflügers Archiv, 434 p.515-524
Journal articleAdrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels
J Gromada, K Bokvist, W G Ding, Sebastian Barg, K Buschard, et al.
(1997) Journal of General Physiology, 110 p.217-228
Journal articleNeurotransmitter-induced inhibition of exocytosis in insulin-secreting beta cells by activation of calcineurin
Erik Renström, Wei-Guang Ding, Krister Bokvist, Patrik Rorsman
(1996) Neuron, 17 p.513-522
Journal articlePKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells
Lena Eliasson, Erik Renström, Carina Ammala, Per-Olof Berggren, Alejandro M. Bertorello, et al.
(1996) Science, 271 p.813-815
Journal articleCooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization
Erik Renström, Lena Eliasson, Krister Bokvist, Patrik Rorsman
(1996) Journal of Physiology, 494 p.41-52
Journal articleDynamics of the cationic, bioelectrical and secretory responses to formycin A in pancreatic islet cells
Philippe Lebrun, Erik Renström, Marie-Hélène Antoine, Krister Bokvist, Mats Holmquist, et al.
(1996) Pflügers Archiv, 431 p.353-362
Journal articleGlucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization
J Gromada, S Dissing, K Bokvist, Erik Renström, J Frokjaer-Jensen, et al.
(1995) Diabetes, 44 p.767-774
Journal articleCo-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells
K Bokvist, Lena Eliasson, C Ammala, Erik Renström, Patrik Rorsman
(1995) EMBO Journal, 14 p.50-57
Journal articleIon channels, electrical activity and insulin secretion
Patrik Rorsman, K Bokvist, C Ammala, L Eliasson, Erik Renström, et al.
(1994) Diabete & metabolisme, 20 p.138-145
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