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Enming Zhang

Research team manager

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Pancreatic β-cell mRNA modification as a marker for type 2 diabetes

Author

  • Erik Renström
  • Enming Zhang

Summary, in English

Diabetes mellitus invariably involves impaired regulation of insulin secretion from pancreatic β cells, as a result of unfavourable environmental influences in combination with aberrant expression of risk genes at either the transcriptional or the translational level. A recent report in Nature Metabolism explores a novel role of mRNA methylation in β-cell function and suggests that its downregulation causes type 2 diabetes.

Department/s

  • Diabetes - Islet Patophysiology
  • EXODIAB: Excellence of Diabetes Research in Sweden

Publishing year

2019-07-29

Language

English

Pages

748-749

Publication/Series

Nature Metabolism

Volume

1

Document type

Journal article review

Publisher

Springer Nature

Topic

  • Endocrinology and Diabetes

Status

Published

Research group

  • Diabetes - Islet Patophysiology
  • LUDC (Lund University Diabetes Centre)

ISBN/ISSN/Other

  • ISSN: 2522-5812