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Emma Ahlqvist

Emma Ahlqvist

Assistant researcher

Emma Ahlqvist

Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control

Author

  • Samuela Pollack
  • Leif Groop
  • Emma Ahlqvist
  • Valeriya Lyssenko
  • Elisabet Agardh
  • Lucia Sobrin

Summary, in English

To identify genetic variants associated with diabetic retinopathy (DR), we performed a large multiethnic genome-wide association study. Discovery included eight European cohorts (n = 3,246) and seven African American cohorts (n = 2,611). We meta-analyzed across cohorts using inverse-variance weighting, with and without liability threshold modeling of glycemic control and duration of diabetes. Variants with a P value

Department/s

  • Genomics, Diabetes and Endocrinology
  • EXODIAB: Excellence of Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health
  • Ophthalmology (Malmö)

Publishing year

2019

Language

English

Pages

441-456

Publication/Series

Diabetes

Volume

68

Issue

2

Document type

Journal article

Publisher

American Diabetes Association Inc.

Topic

  • Endocrinology and Diabetes
  • Medical Genetics

Status

Published

Research group

  • Genomics, Diabetes and Endocrinology
  • Ophthalmology (Malmö)

ISBN/ISSN/Other

  • ISSN: 1939-327X