
Elaine Cowan
Assistant researcher

Elaine Cowan is a Postdoctoral Fellow within the Diabetes Islet Cell Exocytosis Research group at Lund University Diabetes Centre (LUDC). She is a Biomedical Sciences graduate (2002) with a Masters of Research in Diabetes from Ulster University, UK (2003) and PhD in Obesity/Diabetes from Queen´s University Belfast, UK (2016). Her previous research primarily focused on the role of gut peptides in the pathogenesis of type 2 diabetes (T2D) and the impact of mitochondrial dysfunction on pancreatic ß-cell metabolism. Her current research aims to identify miRNAs that regulate mitohondrial genes important in T2D and functionally evaluate the impact of changes in their expression in pancreatic α &/or β-cell models. Another goal of her current research is to globally profile miRNAs in human islet cells and perform miRNA-RNA interaction analysis studies in the same.
Publications
Displaying of publications. Sorted by year, then title.
Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion
Gaurav Verma, Alexander Bowen, Sevda Gheibi, Alexander Hamilton, Sowndarya Muthukumar, et al.
(2022) The Journal of biological chemistry , p.101692-101692
Journal articleMitochondrial clearance of calcium facilitated by MICU2 controls insulin secretion
N. Vishnu, A. Hamilton, A. Bagge, A. Wernersson, E. Cowan, et al.
(2021) Molecular Metabolism, 51
Journal articleHuman enteroviral infection impairs autophagy in clonal INS(832/13) cells and human pancreatic islet cells
Anya Wernersson, Luis Sarmiento, Elaine Cowan, Malin Fex, Corrado M. Cilio
(2020) Diabetologia, 63 p.2372-2384
Journal articleLack of melatonin type 1 receptor results in dysregulated alpha cell function and metabolism
CL Lyons, A Hamilton, D Grajales, L Shcherbina, A Lindqvist, et al.
(2020) Diabetologia, 63 p.231-231
Conference paper: abstractLoss of melatonin receptor 1 in mouse pancreatic islets results in dysregulated glucagon secretion in vitro
C.L. Lyons, E Cowan, D.G. Abellan, C.L.F. Nagorny, H. Mulder, et al.
(2018) Diabetologia, 61 p.244-244
Conference paper: abstract