Visiting research fellow
Spare respiratory capacity, oxidative stress and excitotoxicity
Summary, in English
Chronic exposure to glutamate (glutamate excitotoxicity) exacerbates neuronal damage in the aftermath of stroke and is implicated in a variety of neurodegenerative disorders. mitochondria play a central role in the survival or death of the exposed neuron. calcium, oxidative stress and ATP insufficiency play closely interlocked roles that may be investigated with primary neuronal cultures.
- Department of Experimental Medical Science
Biochemical Society Transactions
- Biochemistry and Molecular Biology
- ISSN: 0300-5127