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Fetal programming of metabolic disease

CRC-seminars
Adverse events in fetal life, including low birth weight and gestational diabetes (GDM) are known risk factors of type 2 diabetes and cardiovascular disease. The original Barker hypothesis of low birth weight being a risk factor of type 2 diabetes has been extensively confirmed, and progress has been made in understanding the underlying physiological and molecular disease mechanisms. However, birth weight remain a crude marker of the foetal environment and the most important questions regarding the mechanisms defining the life course trajectories from exposure to onset of disease remain to be determined. Epigenetic mechanisms including DNA methylations, histone modifications and miRNA expression changes may play a key role between adverse early life exposures and risk of cardiometabolic disease later in life.

Speaker: Charlotte Bröns, Rigshospitalet, Copenhagen, Denmark

Host: Charlotte Ling

Time: 
26 April 2018 16:00 to 17:00
Location: 
Agardh lecture hall, CRC, Jan Waldenströms gata 35, SUS Malmö

About the event

Time: 
26 April 2018 16:00 to 17:00
Location: 
Agardh lecture hall, CRC, Jan Waldenströms gata 35, SUS Malmö

Lund University Diabetes Centre, CRC, SUS Malmö, Jan Waldenströms gata 35, House 91:12. SE-214 28 Malmö. Telephone: +46 40 39 10 00