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Carin Andrén Aronsson

Head of unit

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Risk of pediatric celiac disease according to HLA haplotype and country.

Author

  • Edwin Liu
  • Hye-Seung Lee
  • Carin Andrén Aronsson
  • William A Hagopian
  • Sibylle Koletzko
  • Marian J Rewers
  • George S Eisenbarth
  • Polly J Bingley
  • Ezio Bonifacio
  • Ville Simell
  • Daniel Agardh

Summary, in English

The presence of HLA haplotype DR3-DQ2 or DR4-DQ8 is associated with an increased risk of celiac disease. In addition, nearly all children with celiac disease have serum antibodies against tissue transglutaminase (tTG).

Department/s

  • Diabetes and Celiac Unit
  • EXODIAB: Excellence of Diabetes Research in Sweden

Publishing year

2014

Language

English

Pages

42-49

Publication/Series

New England Journal of Medicine

Volume

371

Issue

1

Document type

Journal article

Publisher

Massachusetts Medical Society

Topic

  • Endocrinology and Diabetes

Keywords

  • Antibodies: blood
  • Autoimmune Diseases: epidemiology
  • Autoimmune Diseases: genetics
  • Celiac Disease: epidemiology
  • Celiac Disease: genetics
  • Europe: epidemiology
  • HLA-DQ Antigens: genetics
  • HLA-DR3 Antigen: genetics
  • HLA-DR4 Antigen: genetics
  • Transglutaminases: immunology
  • United States: epidemiology

Status

Published

Research group

  • Diabetes and Celiac Unit

ISBN/ISSN/Other

  • ISSN: 0028-4793