
Anders Rosengren
Postdoctoral research fellow

Aortic diameter at age 65 in men with newly diagnosed type 2 diabetes
Author
Summary, in English
Objectives. Type 2 diabetes mellitus has been linked to a decreased risk for abdominal aortic aneurysm (aortic diameter ≥30 mm, AAA) development in men. The aim of this study was to evaluate if such an effect is detectable already around the time of diabetes diagnosis. Design. We cross-sectionally compared aortic diameter at ultrasound screening for AAA in 691 men aged 65 years with incipient or newly diagnosed type 2 diabetes (group A) with 18,262 65-year old control men without diabetes (group B). Results. Aortic diameter did not differ between groups (18.8[17.4–20.8] vs. 19.0[17.5–28.7] mm; p = 0.43). AAA prevalence was 2.5% in group A and 1.5% in group B (p = .010). In logistic regression taking group differences in body mass index (BMI), smoking, presence of atherosclerotic disease and hypertension into account, the difference in AAA prevalence was no longer significant (p = .15). Among men in group A, C-peptide (r = .093; p = .034), but not HbA1c (r = .060; p = .24) correlated with aortic diameter. Conclusion. Among 65 year old men aortic diameter and AAA prevalence do not differ between those with newly diagnosed type 2 diabetes and those without diabetes. Putative protective effects of type 2 diabetes mellitus against aortic dilatation and AAA development therefore probably occur later after diagnosis of diabetes.
Department/s
- Vascular Diseases - Clinical Research
- EXODIAB: Excellence of Diabetes Research in Sweden
- EpiHealth: Epidemiology for Health
Publishing year
2017-04-24
Language
English
Pages
202-206
Publication/Series
Scandinavian Cardiovascular Journal
Volume
51
Issue
4
Document type
Journal article
Publisher
Taylor & Francis
Topic
- Endocrinology and Diabetes
Keywords
- Abdominal aortic aneurysm
- aortic diameter
- screening
- type 2 diabetes
- ultrasound
Status
Published
Research group
- Vascular Diseases - Clinical Research
ISBN/ISSN/Other
- ISSN: 1401-7431