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Alexander Perfilyev

Publications

Retrieved from Lund University's publications database

Latest

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Publications

Retrieved from Lund University's publications database

2020
- Epigenome- and Transcriptome-wide Changes in Muscle Stem Cells from Low Birth Weight Men
  Christa Broholm, Rasmus Ribel-Madsen, Line Hjort, Anders Henrik Olsson, Juliane Maria Dorothee Ahlers, et al.
  (2020) Endocrine Research
  Journal article
2019
- Epigenome-wide association study of incident type 2 diabetes in a British population : EPIC-Norfolk study
  Alexia Cardona, Felix R. Day, John R.B. Perry, Marie Loh, Audrey Y. Chu, et al.
  (2019) Diabetes
  Journal article
- Fasting unmasks differential fat and muscle transcriptional regulation of metabolic gene sets in low versus normal birth weight men
  Linn Gillberg, Tina Rönn, Sine Wanda Jørgensen, Alexander Perfilyev, Line Hjort, et al.
  (2019) EBioMedicine
  Journal article
- Glucolipotoxicity alters insulin secretion via epigenetic changes in human islets
  Elin Hall, Josefine Jönsson, Jones K. Ofori, Petr Volkov, Alexander Perfilyev, et al.
  (2019) Diabetes
  Journal article
- Liver DNA methylation of FADS2 associates with FADS2 genotypex 06 Biological Sciences 0604 Genetics
  Paula Walle, Ville Männistö, Vanessa Derenji De Mello, Maija Vaittinen, Alexander Perfilyev, et al.
  (2019) Clinical Epigenetics
  Journal article
2018
- A Single Bout of Electroacupuncture Remodels Epigenetic and Transcriptional Changes in Adipose Tissue in Polycystic Ovary Syndrome
  Milana Kokosar, Anna Benrick, Alexander Perfilyev, Emma Nilsson, Thomas Källman, et al.
  (2018) Scientific Reports
  Journal article
- DNA methylation patterns in human adipose tissue in relation to diet and type 2 diabetes
  Alexander Perfilyev
  (2018) Lund University, Faculty of Medicine Doctoral Dissertation Series
  Dissertation
- Sex Differences in the Methylome and Transcriptome of the Human Liver and Circulating HDL-Cholesterol Levels
  Sonia García-Calzón, Alexander Perfilyev, Vanessa D. de Mello, Jussi Pihlajamäki, Charlotte Ling
  (2018) The Journal of clinical endocrinology and metabolism
  Journal article
2017
- Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects
  Cajsa Davegårdh, Christa Broholm, Alexander Perfilyev, Tora Henriksen, Sonia García-Calzón, et al.
  (2017) BMC Medicine
  Journal article
- Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver
  Sonia García-Calzón, Alexander Perfilyev, Ville Männistö, Vanessa de Mello, Emma A Nilsson, et al.
  (2017) Clinical Epigenetics
  Journal article
- Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver
  Madhusudhan Bysani, Alexander Perfilyev, Vanessa de Mello, Tina Rönn, Emma Nilsson, et al.
  (2017) Epigenomics
  Journal article
- Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action
  Vanessa de Mello, Ashok Matte, Alexander Perfilyev, Ville Männistö, Tina Rönn, et al.
  (2017) Epigenetics
  Journal article
- Impact of polyunsaturated and saturated fat overfeeding on the DNA-methylation pattern in human adipose tissue : A randomized controlled trial
  Alexander Perfilyev, Ingrid Dahlman, Linn Gillberg, Fredrik Rosqvist, David Iggman, et al.
  (2017) American Journal of Clinical Nutrition
  Journal article
2016
- Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.
  Linn Gillberg, Alexander Perfilyev, Charlotte Brøns, Martin Thomasen, Louise G Grunnet, et al.
  (2016) Diabetologia
  Journal article
- DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk
  Tasnim Dayeh, Tiinamaija Tuomi, Peter Almgren, Alexander Perfilyev, Per Anders Jansson, et al.
  (2016) Epigenetics
  Journal article
- Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome
  Milana Kokosar, Anna Benrick, Alexander Perfilyev, Romina Fornes, Emma A Nilsson, et al.
  (2016) Scientific Reports
  Journal article
- Epigenetic programming of adipose-derived stem cells in low birthweight individuals
  Christa Broholm, Anders H. Olsson, Alexander Perfilyev, Ninna S. Hansen, Maren Schrölkamp, et al.
  (2016) Diabetologia
  Journal article
- Human adipogenesis is associated with genome-wide DNA methylation and gene-expression changes
  Christa Broholm, Anders Henrik Olsson, Alexander Perfilyev, Linn Gillberg, Ninna Schiøler Hansen, et al.
  (2016) Epigenomics
  Journal article
2015
- Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels.
  Emma A Nilsson, Ashok Matte, Alexander Perfilyev, Vanessa D de Mello, Pirjo Käkelä, et al.
  (2015) Journal of Clinical Endocrinology and Metabolism
  Journal article
- Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.
  Elisabet Agardh, Annika Lundstig, Alexander Perfilyev, Petr Volkov, Tove Freiburghaus, et al.
  (2015) BMC Medicine
  Journal article
- Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.
  Tina Rönn, Petr Volkov, Linn Gillberg, Milana Kokosar, Alexander Perfilyev, et al.
  (2015) Human Molecular Genetics
  Journal article
- The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.
  I Dahlman, I Sinha, H Gao, D Brodin, A Thorell, et al.
  (2015) International Journal of Obesity
  Journal article
2014
- Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes.
  Emma A Nilsson, Per Anders Jansson, Alexander Perfilyev, Petr Volkov, Maria Pedersen, et al.
  (2014) Diabetes
  Journal article

Publications

Retrieved from Lund University's publications database

Dissertation
- DNA methylation patterns in human adipose tissue in relation to diet and type 2 diabetes
  Alexander Perfilyev
  (2018) Lund University, Faculty of Medicine Doctoral Dissertation Series, 2018:136
Journal article
- Epigenome- and Transcriptome-wide Changes in Muscle Stem Cells from Low Birth Weight Men
  Christa Broholm, Rasmus Ribel-Madsen, Line Hjort, Anders Henrik Olsson, Juliane Maria Dorothee Ahlers, et al.
  (2020) Endocrine Research, 45 p.58-71
- Glucolipotoxicity alters insulin secretion via epigenetic changes in human islets
  Elin Hall, Josefine Jönsson, Jones K. Ofori, Petr Volkov, Alexander Perfilyev, et al.
  (2019) Diabetes, 68 p.1965-1974
- Fasting unmasks differential fat and muscle transcriptional regulation of metabolic gene sets in low versus normal birth weight men
  Linn Gillberg, Tina Rönn, Sine Wanda Jørgensen, Alexander Perfilyev, Line Hjort, et al.
  (2019) EBioMedicine, 47 p.341-351
- Liver DNA methylation of FADS2 associates with FADS2 genotypex 06 Biological Sciences 0604 Genetics
  Paula Walle, Ville Männistö, Vanessa Derenji De Mello, Maija Vaittinen, Alexander Perfilyev, et al.
  (2019) Clinical Epigenetics, 11
- Epigenome-wide association study of incident type 2 diabetes in a British population : EPIC-Norfolk study
  Alexia Cardona, Felix R. Day, John R.B. Perry, Marie Loh, Audrey Y. Chu, et al.
  (2019) Diabetes, 68 p.2315-2326
- A Single Bout of Electroacupuncture Remodels Epigenetic and Transcriptional Changes in Adipose Tissue in Polycystic Ovary Syndrome
  Milana Kokosar, Anna Benrick, Alexander Perfilyev, Emma Nilsson, Thomas Källman, et al.
  (2018) Scientific Reports, 8
- Sex Differences in the Methylome and Transcriptome of the Human Liver and Circulating HDL-Cholesterol Levels
  Sonia García-Calzón, Alexander Perfilyev, Vanessa D. de Mello, Jussi Pihlajamäki, Charlotte Ling
  (2018) The Journal of clinical endocrinology and metabolism, 103 p.4395-4408
- Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver
  Sonia García-Calzón, Alexander Perfilyev, Ville Männistö, Vanessa de Mello, Emma A Nilsson, et al.
  (2017) Clinical Epigenetics, 9 p.1-9
- Impact of polyunsaturated and saturated fat overfeeding on the DNA-methylation pattern in human adipose tissue : A randomized controlled trial
  Alexander Perfilyev, Ingrid Dahlman, Linn Gillberg, Fredrik Rosqvist, David Iggman, et al.
  (2017) American Journal of Clinical Nutrition, 105 p.991-1000
- Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action
  Vanessa de Mello, Ashok Matte, Alexander Perfilyev, Ville Männistö, Tina Rönn, et al.
  (2017) Epigenetics, 12 p.287-295
- Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects
  Cajsa Davegårdh, Christa Broholm, Alexander Perfilyev, Tora Henriksen, Sonia García-Calzón, et al.
  (2017) BMC Medicine, 15 p.1-27
- Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver
  Madhusudhan Bysani, Alexander Perfilyev, Vanessa de Mello, Tina Rönn, Emma Nilsson, et al.
  (2017) Epigenomics, 9 p.105-122
- Human adipogenesis is associated with genome-wide DNA methylation and gene-expression changes
  Christa Broholm, Anders Henrik Olsson, Alexander Perfilyev, Linn Gillberg, Ninna Schiøler Hansen, et al.
  (2016) Epigenomics, 8 p.1601-1617
- Epigenetic programming of adipose-derived stem cells in low birthweight individuals
  Christa Broholm, Anders H. Olsson, Alexander Perfilyev, Ninna S. Hansen, Maren Schrölkamp, et al.
  (2016) Diabetologia, 59 p.2664-2673
- DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk
  Tasnim Dayeh, Tiinamaija Tuomi, Peter Almgren, Alexander Perfilyev, Per Anders Jansson, et al.
  (2016) Epigenetics, 11 p.482-488
- Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.
  Linn Gillberg, Alexander Perfilyev, Charlotte Brøns, Martin Thomasen, Louise G Grunnet, et al.
  (2016) Diabetologia, 59 p.799-812
- Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome
  Milana Kokosar, Anna Benrick, Alexander Perfilyev, Romina Fornes, Emma A Nilsson, et al.
  (2016) Scientific Reports, 6
- Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.
  Elisabet Agardh, Annika Lundstig, Alexander Perfilyev, Petr Volkov, Tove Freiburghaus, et al.
  (2015) BMC Medicine, 13
- Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels.
  Emma A Nilsson, Ashok Matte, Alexander Perfilyev, Vanessa D de Mello, Pirjo Käkelä, et al.
  (2015) Journal of Clinical Endocrinology and Metabolism, 100 p.1491-1501
- Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.
  Tina Rönn, Petr Volkov, Linn Gillberg, Milana Kokosar, Alexander Perfilyev, et al.
  (2015) Human Molecular Genetics, 24 p.3792-3813
- The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.
  I Dahlman, I Sinha, H Gao, D Brodin, A Thorell, et al.
  (2015) International Journal of Obesity, 39 p.910-919
- Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes.
  Emma A Nilsson, Per Anders Jansson, Alexander Perfilyev, Petr Volkov, Maria Pedersen, et al.
  (2014) Diabetes, 63 p.2962-2976

11 December 2019

Alexander Perfilyev

E-mail: alexander [dot] perfilyev [at] med [dot] lu [dot] se

Assistant researcher

Diabetes - Epigenetics

Service point:33

Postdoctoral fellow

EXODIAB: Excellence in Diabetes Research in Sweden

My profile in Lund University research portal

Lund University Diabetes Centre

Excellence of diabetes research in Sweden

Alexander Perfilyev

Publications

Publications

Publications