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Åke Lernmark

Principal investigator

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HLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis

Author

  • S ‐A Ivarsson
  • S. ERIKSSON
  • I. KOCKUM
  • Å LERNMARK
  • S. LINDGREN
  • K. O. NILSSON
  • G. SUNDKVIST
  • R. WASSMUTH

Summary, in English

Abstract. Two unrelated young males with the unusual simultaneous presence of insulin‐dependent diabetes mellitus, ulcerative colitis and primary sclerosing cholangitis are reported. Both patients manifested homozygosity for the DR3‐DQw2 (DQB*0201) HLA genotypes. We believe that homozygosity for this genotype may predispose for this type of multi‐organ autoimmune disease. 1993 Blackwell Publishing Ltd

Department/s

  • Diabetes and Celiac Unit
  • Paediatric Endocrinology
  • Department of Clinical Sciences, Malmö

Publishing year

1993-01-01

Language

English

Pages

281-286

Publication/Series

Journal of Internal Medicine

Volume

233

Issue

3

Document type

Journal article

Publisher

Wiley-Blackwell

Topic

  • Endocrinology and Diabetes

Keywords

  • diabetes mellitus type I
  • sclerosing cholangitis
  • ulcerative colitis

Status

Published

Research group

  • Diabetes and Celiac Unit
  • Paediatric Endocrinology

ISBN/ISSN/Other

  • ISSN: 0954-6820