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Baseline heterogeneity in glucose metabolism marks the risk for type 1 diabetes and complicates secondary prevention.

  • Helena Larsson
  • Christer Larsson
  • Åke Lernmark
Publishing year: 2015
Language: English
Pages: 473-481
Publication/Series: Acta Diabetologica
Volume: 52
Issue: 3
Document type: Journal article
Publisher: Springer

Abstract english

Non-diabetic children with multiple islet autoantibodies were recruited to a secondary prevention trial. The objective was to determine the predictive value of baseline (1) HbA1c and metabolic variables derived from intravenous (IvGTT) and oral glucose tolerance tests (OGTT), (2) insulin resistance and (3) number, type and levels of islet autoantibodies, for progression to type 1 diabetes.


  • Endocrinology and Diabetes


  • Paediatric Endocrinology
  • Diabetes and Celiac Unit
  • ISSN: 1432-5233
E-mail: ake [dot] lernmark [at] med [dot] lu [dot] se

Principal investigator

Diabetes and Celiac Unit

+46 40 39 19 01

+46 70 616 47 79


Jan Waldenströms gata 35, Malmö


Lund University Diabetes Centre, CRC, SUS Malmö, Jan Waldenströms gata 35, House 91:12. SE-214 28 Malmö. Telephone: +46 40 39 10 00