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Åke Lernmark

Principal investigator

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Effects of pancreozymin and secretin on insulin release and the role of the exocrine pancreas

Author

  • Å Danielsson
  • Å Lernmark

Summary, in English

Mouse pancreatic islets microdissected free from, or surrounded by, exocrine cells were used to study the effects of secretin and choleeystokinm-pancreozymin on insulin release. Both secretin and cholecystokinin-pancreozymin potentiated glucose-stimulated insulin release regardless of whether exocrine cells were present. The results fail to support the idea that the presence of the exocrine parenchyma is essential for elicitation of insulin release by these gastrointestinal hormones.

Publishing year

1974-10-01

Language

English

Pages

407-409

Publication/Series

Diabetologia

Volume

10

Issue

5

Document type

Journal article

Publisher

Springer

Topic

  • Endocrinology and Diabetes

Keywords

  • exocrine cells
  • Insulin release
  • mouse islets
  • pancreozymin
  • secretin

Status

Published

ISBN/ISSN/Other

  • ISSN: 0012-186X