Your browser has javascript turned off or blocked. This will lead to some parts of our website to not work properly or at all. Turn on javascript for best performance.

The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

Default user image.

Åke Lernmark

Principal investigator

Default user image.

The Better Diabetes Diagnosis (BDD) study – A review of a nationwide prospective cohort study in Sweden

Author

  • M. Persson
  • C. Becker
  • H. Elding Larsson
  • Lernmark
  • G. Forsander
  • S. A. Ivarsson
  • J. Ludvigsson
  • U. Samuelsson
  • C. Marcus
  • A. Carlsson

Summary, in English

The incidence of type 1 diabetes (T1D) in Sweden is one of the highest in the world. However, the possibility of other types of diabetes must also be considered. In addition, individuals with T1D constitute a heterogeneous group. A precise classification of diabetes is a prerequisite for optimal outcome. For precise classification, knowledge on the distribution of genetic factors, biochemical markers and clinical features in individuals with new onset of diabetes is needed. The Better Diabetes Diagnosis (BDD), is a nationwide study in Sweden with the primary aim to facilitate a more precise classification and diagnosis of diabetes in order to enable the most adequate treatment for each patient. Secondary aims include identification of risk factors for diabetes-related co-morbidities. Since 2005, data on almost all children and adolescents with newly diagnosed diabetes in Sweden are prospectively collected and including heredity of diabetes, clinical symptoms, levels of C peptide, genetic analyses and detection of autoantibodies. Since 2011, analyses of HLA profile, autoantibodies and C peptide levels are part of clinical routine in Sweden for all pediatric patients with suspected diagnosis of diabetes. In this review, we present the methods and main results of the BDD study so far and discuss future aspects.

Department/s

  • Paediatric Endocrinology
  • Diabetes and Celiac Unit
  • PediatricCeliaki/Diabetes
  • EXODIAB: Excellence in Diabetes Research in Sweden

Publishing year

2018-06-01

Language

English

Pages

236-244

Publication/Series

Diabetes Research and Clinical Practice

Volume

140

Document type

Journal article review

Publisher

Elsevier

Topic

  • Endocrinology and Diabetes

Status

Published

Research group

  • Paediatric Endocrinology
  • Diabetes and Celiac Unit
  • PediatricCeliaki/Diabetes

ISBN/ISSN/Other

  • ISSN: 0168-8227