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Åke Lernmark

Principal investigator

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Flow-injection immunoassays : Present and future

Author

  • Cy H. Pollema
  • Jaromir Ruzicka
  • Åke Lernmark
  • Gary D. Christian

Summary, in English

The recent development of the flow-injection immunoassay (FIIA), beginning with one of the first publications in 1980 by Lim and Miller, has resulted in a growing field which combines the precise and reproducible timing of flow-injection analysis (FIA) with immunoassays to yield assays which are carried out in a nonequilibrium time frame. These often faster assay methods require small volumes of sample and reduced sample handling. The advancement of this field is briefly reviewed in this paper with respect to the general methods and detection schemes applied. A novel method utilizing sequential injection (SI) is also introduced. The method uses immunomagnetic beads to create a renewable reaction column which does not require in-line regeneration.

Publishing year

1992-01-01

Language

English

Pages

121-128

Publication/Series

Microchemical Journal

Volume

45

Issue

2

Document type

Journal article

Publisher

Elsevier

Topic

  • Medicinal Chemistry

Status

Published

ISBN/ISSN/Other

  • ISSN: 0026-265X