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Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease.

Author:
  • Helena Larsson
  • Kendra Vehik
  • Patricia Gesualdo
  • Beena Akolkar
  • William Hagopian
  • Jeffery Krischer
  • Åke Lernmark
  • Marian Rewers
  • Olli Simell
  • Jin-Xiong She
  • Anette Ziegler
  • Michael J Haller
Publishing year: 2014
Language: English
Pages: 118-126
Publication/Series: Pediatric Diabetes
Volume: 15
Issue: 2
Document type: Journal article
Publisher: Wiley-Blackwell

Abstract english

The Environmental Determinants of Diabetes in the Young (TEDDY) study is designed to identify environmental exposures triggering islet autoimmunity and type 1 diabetes (T1D) in genetically high-risk children. We describe the first 100 participants diagnosed with T1D, hypothesizing that (i) they are diagnosed at an early stage of disease, (ii) a high proportion are diagnosed by an oral glucose tolerance test (OGTT), and (iii) risk for early T1D is related to country, population, human leukocyte antigen (HLA)-genotypes and immunological markers.

Keywords

  • Endocrinology and Diabetes
  • Pediatrics

Other

Published
  • Paediatric Endocrinology
  • Diabetes and Celiac Unit
  • ISSN: 1399-543X
E-mail: ake [dot] lernmark [at] med [dot] lu [dot] se

Principal investigator

Diabetes and Celiac Unit

+46 40 39 19 01

+46 70 616 47 79

60:11:015

Jan Waldenströms gata 35, Malmö

33

Lund University Diabetes Centre, CRC, SUS Malmö, Jan Waldenströms gata 35, House 91:12. SE-214 28 Malmö. Telephone: +46 40 39 10 00