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Åke Lernmark

Principal investigator

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Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease.

Author

  • Helena Larsson
  • Kendra Vehik
  • Patricia Gesualdo
  • Beena Akolkar
  • William Hagopian
  • Jeffery Krischer
  • Åke Lernmark
  • Marian Rewers
  • Olli Simell
  • Jin-Xiong She
  • Anette Ziegler
  • Michael J Haller

Summary, in English

The Environmental Determinants of Diabetes in the Young (TEDDY) study is designed to identify environmental exposures triggering islet autoimmunity and type 1 diabetes (T1D) in genetically high-risk children. We describe the first 100 participants diagnosed with T1D, hypothesizing that (i) they are diagnosed at an early stage of disease, (ii) a high proportion are diagnosed by an oral glucose tolerance test (OGTT), and (iii) risk for early T1D is related to country, population, human leukocyte antigen (HLA)-genotypes and immunological markers.

Department/s

  • Paediatric Endocrinology
  • Diabetes and Celiac Unit
  • EXODIAB: Excellence in Diabetes Research in Sweden

Publishing year

2014

Language

English

Pages

118-126

Publication/Series

Pediatric Diabetes

Volume

15

Issue

2

Document type

Journal article

Publisher

Wiley-Blackwell

Topic

  • Endocrinology and Diabetes
  • Pediatrics

Status

Published

Research group

  • Paediatric Endocrinology
  • Diabetes and Celiac Unit

ISBN/ISSN/Other

  • ISSN: 1399-543X