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Åke Lernmark

Principal investigator

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Immune complexes in insulin-dependent diabetes

Author

  • G. Contreas
  • A. Lernmark
  • E. R. Mathiesen
  • T. Deckert

Summary, in English

Circulating immune complexes (IC) were studied in 40 newly-diagnosed insulin-dependent diabetics (IDDM), 40 long duration IDDM, and 16 healthy controls. IC were detected by the solid-phase Clq test (SP-Clq). IDDM patients at diagnosis (25%) showed a higher incidence of IC compared to the long duration IDDM patients (15%) and the control group (7%). There was no difference in the prevalence of circulating IC in long duration IDDM with clinical nephropathy and those without clinical nephropathy. IC detected by Sp-Clq, seem to be associated with the clinical onset of IDDM but not with the development of nephropathy.

Publishing year

1985-01-01

Language

English

Pages

129-132

Publication/Series

Biomedica Biochimica Acta

Volume

44

Issue

1

Document type

Journal article

Publisher

Akademie Verlag

Status

Published

ISBN/ISSN/Other

  • ISSN: 0232-766X