Vaccination mot typ 1-diabetes framme vid kliniska försöksstadiet
Vaccination against type I diabetes at the clinical trial stage
Summary, in English
The occurrence of type I diabetes is associated with autoimmunity against insulin, glutamate decarboxylase (GAD65) and the transmembrane protein IA-2. Experiments in the spontaneously diabetic NOD mouse and the BB rat have shown early autoantigen treatment to confer protection from diabetes. The question remains of whether human type I diabetes can be prevented by autoantigen 'vaccination'.
Swedish Medical Association
- ISSN: 0023-7205