
Åke Lernmark
Principal investigator
Immunogenetics of Type 1 Diabetes
The HLA DQ locus is the major genetic risk factor for both type 1 diabetes and celiac disease. Both diseases are also linked to several non−HLA candidate genes, which may modify risk. Several but different etiological factors in the environment have also been implicated in the disease risk for type 1 diabetes and celiac disease. The pathogenesis of type 1 diabetes is strongly associated with the appearance of autoantibodies against GAD65, IA−2, ZnT8 and insulin, alone or in combination. Our laboratory cloned human islet GAD65 and developed a novel assay now in worldwide use to detect these autoantibodies and other autoantibodies such as those against tissue transglutaminase that predict celiac disease.
Publications
Displaying of publications. Sorted by year, then title.
Multiplex agglutination-PCR (ADAP) autoantibody assays compared to radiobinding autoantibodies in type 1 diabetes and celiac disease
Felipe de Jesus Cortez, Alexander Lind, Anita Ramelius, Rasmus Bennet, Peter V Robinson, et al.
(2022) Journal of Immunological Methods
Journal articleTelomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study
Carina Törn, Xiang Liu, Suna Onengut-Gumuscu, Kevin M Counts, Jose Leonardo Moreno, et al.
(2022) Scientific Reports, 12 p.4516-4516
Journal articleHeterogeneity of beta-cell function in subjects with multiple islet autoantibodies in the TEDDY family prevention study - TEFA
Maria Månsson Martinez, Lampros Spiliopoulos, Falastin Salami, Daniel Agardh, Jorma Toppari, et al.
(2022) Clinical diabetes and endocrinology, 7
Journal articleEnteroviruses and Type 1 Diabetes : Multiple Mechanisms and Factors?
Richard E Lloyd, Manasi Tamhankar, Åke Lernmark
(2022) Annual Review of Medicine, 73
Journal articleProgression of type 1 diabetes from latency to symptomatic disease is predicted by distinct autoimmune trajectories
Bum Chul Kwon, Vibha Anand, Peter Achenbach, Jessica L Dunne, William Hagopian, et al.
(2022) Nature Communications, 13 p.1-9
Journal articleSimplifying prediction of disease progression in pre-symptomatic type 1 diabetes using a single blood sample
Naiara G Bediaga, Connie S N Li-Wai-Suen, Michael J Haller, Stephen E Gitelman, Carmella Evans-Molina, et al.
(2021) Diabetologia, 64 p.2432-2444
Journal articleCharacteristics of children diagnosed with type 1 diabetes before vs after 6 years of age in the TEDDY cohort study
Jeffrey P. Krischer, Xiang Liu, Åke Lernmark, William A. Hagopian, Marian J. Rewers, et al.
(2021) Diabetologia, 64 p.2247-2257
Journal articleEtiology of Autoimmune Islet Disease : Timing Is Everything
Åke Lernmark
(2021) Diabetes, 70 p.1431-1439
Journal articleThe KAG motif of HLA-DRB1 (β71, β74, β86) predicts seroconversion and development of type 1 diabetes
Lue Ping Zhao, George K Papadopoulos, Terry P Lybrand, Antonis K Moustakas, George P Bondinas, et al.
(2021) EBioMedicine, 69
Journal articleComplete blood counts with red blood cell determinants associate with reduced beta-cell function in seroconverted Swedish TEDDY children
Falastin Salami, Roy N.Tamura, Helena Elding Larsson, Åke Lernmark, Carina Törn
(2021) Endocrinology, Diabetes and Metabolism, 4
Journal articleNine residues in HLA-DQ molecules determine with susceptibility and resistance to type 1 diabetes among young children in Sweden
Lue Ping Zhao, George K Papadopoulos, Antonis K Moustakas, George P Bondinas, Annelie Carlsson, et al.
(2021) Scientific Reports, 11
Journal articleAssociations of breastfeeding with childhood autoimmunity, allergies, and overweight : The Environmental Determinants of Diabetes in the Young (TEDDY) study
Sandra Hummel, Andreas Weiß, Ezio Bonifacio, Daniel Agardh, Beena Akolkar, et al.
(2021) The American journal of clinical nutrition, 114 p.134-142
Journal articleBeta cell function in participants with single or multiple islet autoantibodies at baseline in the TEDDY Family Prevention Study : TEFA
Maria Månsson Martinez, Falastin Salami, Helena Elding Larsson, Jorma Toppari, Åke Lernmark, et al.
(2021) Endocrinology, Diabetes & Metabolism, 4
Journal articleTranscriptional networks in at-risk individuals identify signatures of type 1 diabetes progression
Louis-Pascal Xhonneux, Oliver Knight, Åke Lernmark, Ezio Bonifacio, William A Hagopian, et al.
(2021) Science Translational Medicine, 13
Journal articleThe Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats
Marika Bogdani, Linda Faxius, Malin Fex, Anita Ramelius, Anya Wernersson, et al.
(2021) Frontiers in Endocrinology, 12
Journal articleAn Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood
Ezio Bonifacio, Andreas Weiß, Christiane Winkler, Markus Hippich, Marian J Rewers, et al.
(2021) Diabetes Care, 44 p.2260-2268
Journal articleChildren's erythrocyte fatty acids are associated with the risk of islet autoimmunity
Sari Niinistö, Iris Erlund, Hye-Seung Lee, Ulla Uusitalo, Irma Salminen, et al.
(2021) Scientific Reports, 11
Journal articleFirst-appearing islet autoantibodies for type 1 diabetes in young children : maternal life events during pregnancy and the child's genetic risk
Suzanne Bennett Johnson, Kristian F Lynch, Roswith Roth, Markus Lundgren, Hemang M Parikh, et al.
(2021) Diabetologia, 64 p.591-602
Journal articlePlasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes : the TEDDY Study
Qian Li, Xiang Liu, Jimin Yang, Iris Erlund, Åke Lernmark, et al.
(2021) Diabetes, 70 p.282-292
Journal articleImmunocyte single cell analysis of vaccine-induced narcolepsy
Alexander Lind, Falastin Salami, Anne-Marie Landtblom, Lars Palm, Åke Lernmark, et al.
(2021) European Journal of Immunology, 51 p.247-249
Journal article (letter)Neutralizing Ljungan virus antibodies in children with newly diagnosed type 1 diabetes
Annika Lundstig, Sharia L McDonald, Marlena Maziarz, William C Weldon, Fariba Vaziri-Sani, et al.
(2021) The Journal of general virology, 102
Journal articleMetabolomics Profiling of Patients With A-β+ Ketosis-Prone Diabetes During Diabetic Ketoacidosis
Farook Jahoor, Jean W. Hsu, Paras B. Mehta, Kelly R. Keene, Ruchi Gaba, et al.
(2021) Diabetes, 70 p.1898-1909
Journal articlePeriodontal conditions, retinopathy, and serum markers in individuals with type 1 diabetes
Cecilia Widén, Helene Holmer, Susanna Sättlin, Stefan Renvert, Åke Lernmark, et al.
(2020) Journal of Periodontology, 91 p.1436-1443
Journal articleCharacterization of plasma lipidomics in adolescent subjects with increased risk for type 1 diabetes in the DiPiS cohort
Agnes Andersson Svärd, Simranjeet Kaur, Kajetan Trôst, Tommi Suvitaival, Åke Lernmark, et al.
(2020) Metabolomics, 16
Journal articleHierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study
Kendra Vehik, Ezio Bonifacio, Ake Lernmark, Liping Yu, Alistair Williams, et al.
(2020) Diabetes Care, 43 p.2066-2073
Journal articleMotifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children
Lue Ping Zhao, George K Papadopoulos, William W Kwok, Antonis K Moustakas, George P Bondinas, et al.
(2020) Diabetes, 69 p.1573-1587
Journal articleScreening for autoantibody targets in post-vaccination narcolepsy using proteome arrays
Alexander Lind, Daniel Eriksson, Omar Akel, Anita Ramelius, Lars Palm, et al.
(2020) Scandinavian Journal of Immunology, 91
Journal articleLongitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study
Qian Li, Hemang Parikh, Martha D Butterworth, Åke Lernmark, William Hagopian, et al.
(2020) Diabetes, 69 p.465-476
Journal articleHyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates
Marika Bogdani, Cate Speake, Mathew J Dufort, Pamela Y Johnson, Megan J Larmore, et al.
(2020) Diabetologia, 63 p.549-560
Journal articleAbsence of Islet Autoantibodies and Modestly Raised Glucose Values at Diabetes Diagnosis Should Lead to Testing for MODY : Lessons From a 5-Year Pediatric Swedish National Cohort Study
Annelie Carlsson, Maggie Shepherd, Sian Ellard, Michael Weedon, Åke Lernmark, et al.
(2020) Diabetes Care, 43 p.82-89
Journal articlePlasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes : the TEDDY study
Markus Mattila, Iris Erlund, Hye Seung Lee, Sari Niinistö, Ulla Uusitalo, et al.
(2020) Diabetologia, 63 p.278-286
Journal articleDecreased HLA-DQ expression on peripheral blood cells in children with varying number of beta cell autoantibodies
Agnes Andersson Svärd, Marlena Maziarz, Anita Ramelius, Markus Lundgren, Åke Lernmark, et al.
(2020) Journal of Translational Autoimmunity, 3
Journal articleA combined risk score enhances prediction of type 1 diabetes among susceptible children
L.A. Ferrat, K. Vehik, S.A. Sharp, Å. Lernmark, M.J. Rewers, et al.
(2020) Nature Medicine, 26 p.1247-1255
Journal articleNext Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes
Lue Ping Zhao, George K Papadopoulos, William W Kwok, Antonis K Moustakas, George P Bondinas, et al.
(2020) Diabetes, 69 p.2523-2535
Journal articleProspective virome analyses in young children at increased genetic risk for type 1 diabetes
Kendra Vehik, Kristian F Lynch, Matthew C Wong, Xiangjun Tian, Matthew C Ross, et al.
(2019) Nature Medicine, 25 p.1865-1872
Journal articleReduced display of conformational epitopes in the N-terminal truncated GAD65 isoform : relevance for people with stiff person syndrome or DQ8/8-positive Type 1 diabetes mellitus
C. S. Hampe, J. R. Radtke, A. Wester, A. Carlsson, E. Cedervall, et al.
(2019) Diabetic Medicine, 36 p.1375-1383
Journal articleAutoimmune (type 1) diabetes
Ida Lindbladh, Agnes Andersson Svärd, Åke Lernmark
(2019) The Autoimmune Diseases , p.769-787
Book chapterAutoantibodies in Pandemrix®-induced narcolepsy : Nine candidate autoantigens fail the conformational autoantibody test
Madeleine Wallenius, Alexander Lind, Omar Akel, Emma Karlsson, Markus Svensson, et al.
(2019) Autoimmunity, 52 p.185-191
Journal articleGenetic Variation Within the HLA-DRA1 Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes
Özkan Aydemir, Janelle A Noble, Jeffrey A Bailey, Åke Lernmark, Patrick Marsh, et al.
(2019) Diabetes, 68 p.1523-1527
Journal articlePredicting Islet Cell Autoimmunity and Type 1 Diabetes : An 8-Year TEDDY Study Progress Report
Jeffrey P Krischer, Xiang Liu, Kendra Vehik, Beena Akolkar, William A Hagopian, et al.
(2019) Diabetes Care, 42 p.1051-1060
Journal articleEleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4 and 5 Include Potentially "Causal Residues" Responsible for the Risk of Childhood Type 1 Diabetes
Lue Ping Zhao, George K Papadopoulos, Bill Kwok, Bryan Xu, Matthew Kong, et al.
(2019) Diabetes, 68 p.1692-1704
Journal articleMaternal dietary supplement use and development of islet autoimmunity in the offspring : TEDDY study
Katherine Silvis, Carin A. Aronsson, Xiang Liu, Ulla Uusitalo, Jimin Yang, et al.
(2019) Pediatric Diabetes, 20 p.86-92
Journal articleRationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes
Jessica L. Dunne, Sarah J. Richardson, Mark A. Atkinson, Maria E. Craig, Knut Dahl-Jørgensen, et al.
(2019) Diabetologia, 62 p.744-753
Journal articleProgression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors : Results from the prospective TEDDY study
Andreas Beyerlein, Ezio Bonifacio, Kendra Vehik, Markus Hippich, Christiane Winkler, et al.
(2019) Journal of Medical Genetics, 56 p.602-605
Journal articleTime-resolved autoantibody profiling facilitates stratification of preclinical type 1 diabetes in children
David Endesfelder, Wolfgang zu Castell, Ezio Bonifacio, Marian Rewers, William A. Hagopian, et al.
(2019) Diabetes, 68 p.119-130
Journal articleGenetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families
Markus Hippich, Andreas Beyerlein, William A. Hagopian, Jeffrey P. Krischer, Kendra Vehik, et al.
(2019) Diabetes, 68 p.847-857
Journal articleHLA high-resolution typing by next-generation sequencing in Pandemrix-induced narcolepsy
Alexander Lind, Omar Akel, Madeleine Wallenius, Anita Ramelius, Marlena Maziarz, et al.
(2019) PLoS ONE, 14 p.1-13
Journal articleMetabolite-related dietary patterns and the development of islet autoimmunity
Randi K. Johnson, Åke Lernmark, Carin Andrén Aronsson, Maria Ask, Jenny Bremer, et al.
(2019) Scientific Reports, 9
Journal articleTissue transglutaminase autoantibodies in children with newly diagnosed type 1 diabetes are related to human leukocyte antigen but not to islet autoantibodies : A Swedish nationwide prospective population-based cohort study
Mara Cerqueiro Bybrant, Lena Grahnquist, Eva Örtqvist, Cecilia Andersson, Gun Forsander, et al.
(2018) Autoimmunity, 51 p.221-227
Journal articleThe Better Diabetes Diagnosis (BDD) study – A review of a nationwide prospective cohort study in Sweden
M. Persson, C. Becker, H. Elding Larsson, Lernmark, G. Forsander, et al.
(2018) Diabetes Research and Clinical Practice, 140 p.236-244
Journal article reviewFirst trimester enterovirus IgM and beta cell autoantibodies in mothers to children affected by type 1 diabetes autoimmunity before 7 years of age
Alexander Lind, Kristian F. Lynch, Markus Lundgren, Åke Lernmark, Peter Almgren, et al.
(2018) Journal of Reproductive Immunology, 127 p.1-6
Journal articleNovel subgroups of adult-onset diabetes and their association with outcomes : A data-driven cluster analysis of six variables
Emma Ahlqvist, Petter Storm, Annemari Käräjämäki, Mats Martinell, Mozhgan Dorkhan, et al.
(2018) The Lancet Diabetes and Endocrinology, 6 p.361-369
Journal articleGenetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes : A prospective study in children
Ezio Bonifacio, Andreas Beyerlein, Markus Hippich, Christiane Winkler, Kendra Vehik, et al.
(2018) PLoS Medicine, 15
Journal articleGenetic risk scores in adult-onset type 1 diabetes
Richard David Leslie, Åke Lernmark
(2018) The Lancet Diabetes and Endocrinology, 6 p.168-169
Journal article (letter)Early infant diet and islet autoimmunity in the TEDDY study
Ulla Uusitalo, Hye Seung Lee, Carin Andrén Aronsson, Kendra Vehik, Jimin Yang, et al.
(2018) Diabetes Care, 41 p.522-530
Journal articleHLA, infections and inflammation in early stages of atherosclerosis in children with type 1 diabetes
Michal Odermarsky, Erkki Pesonen, Timo Sorsa, Åke Lernmark, Pirkko Pussinen, et al.
(2018) Acta Diabetologica, 55 p.41-47
Journal articleCaesarean Section on The Risk of Celiac Disease in the Offspring : The Teddy Study
Sibylle Koletzko, Hye-Seung Lee, Andreas Beyerlein, Carin A. Aronsson, Michael Hummel, et al.
(2018) Journal of Pediatric Gastroenterology and Nutrition, 66 p.417-424
Journal articlePandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children
Helena Elding Larsson, Kristian F. Lynch, Maria Lönnrot, Michael J Haller, Åke Lernmark, et al.
(2018) Diabetologia, 61 p.193-202
Journal articleGestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident β-cell autoantibodies
Kristian F. Lynch, Hye-Seung Lee, Carina Törn, Kendra Vehik, Jeffrey P. Krischer, et al.
(2018) Journal of Autoimmunity, 86 p.93-103
Journal articleEarly deficits in insulin secretion, beta cell mass and islet blood perfusion precede onset of autoimmune type 1 diabetes in BioBreeding rats
Anya Medina, Saba Parween, Sara Ullsten, Neelanjan Vishnu, Yuk Ting Siu, et al.
(2018) Diabetologia, 61 p.896-905
Journal articlePlasma 25-Hydroxyvitamin D concentration and risk of islet autoimmunity
Jill M. Norris, Hye Seung Lee, Brittni Frederiksen, Iris Erlund, Ulla Uusitalo, et al.
(2018) Diabetes, 67 p.146-154
Journal articleIdentification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort
Ashok Sharma, Xiang Liu, David Hadley, William Hagopian, Wei Min Chen, et al.
(2018) Journal of Autoimmunity, 89 p.90-100
Journal article10 år med BDD-studien har gett bättre diabetesdiagnos hos barn : Studiens analysbatteri är nu klinisk rutin och kunskapen om olika diabetessjukdomar har ökat
Annelie Carlsson, Gun Forsander, Sten Ivarsson, Helena Elding Larsson, Åke Lernmark, et al.
(2018) Läkartidningen, 115 p.484-484
Journal articleThe Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update
Heikki Hyöty, Åke Lernmark, William Hagopian, Jin-Xiong She, Desmond A Schatz, et al.
(2018) Current Diabetes Reports, 18
Journal articleReduction in White Blood Cell, Neutrophil, and Red Blood Cell Counts Related to Sex, HLA, and Islet Autoantibodies in Swedish TEDDY Children at Increased Risk for Type 1 Diabetes
Falastin Salami, Hye Seung Lee, Eva Freyhult, Helena Elding Larsson, Åke Lernmark, et al.
(2018) Diabetes, 67 p.2329-2336
Journal articleTemporal development of the gut microbiome in early childhood from the TEDDY study
Christopher J. Stewart, Nadim J. Ajami, Jacqueline L. O’Brien, Diane S. Hutchinson, Daniel P. Smith, et al.
(2018) Nature, 562 p.583-588
Journal article (letter)The human gut microbiome in early-onset type 1 diabetes from the TEDDY study
Tommi Vatanen, Eric A. Franzosa, Randall Schwager, Surya Tripathi, Timothy D. Arthur, et al.
(2018) Nature, 562 p.589-594
Journal article (letter)Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity
Kaisa M Kemppainen, Kendra Vehik, Kristian F Lynch, Helena Elding Larsson, Ronald J Canepa, et al.
(2017) JAMA Pediatrics, 171 p.1217-1225
Journal articleCo-occurrence of Type 1 Diabetes and Celiac Disease Autoimmunity
William Hagopian, Hye Seung Lee, Edwin Liu, Marian Rewers, Jin Xiong She, et al.
(2017) Pediatrics, 140
Journal articleAre Perinatal Events Risk Factors for Childhood Thyroid Autoimmunity?
Berglind Jonsdottir, Markus Lundgren, Sara Wallengren, Åke Lernmark, Ida Jönsson, et al.
(2017) European Thyroid Journal, 6 p.298-306
Journal articleThe Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History to the Progression from Multiple Autoantibodies to Type 1 Diabetes:A TEDDY Study Report : A TEDDY Study Report
Jeffrey P. Krischer, Xiang Liu, Åke Lernmark, William A. Hagopian, Marian J. Rewers, et al.
(2017) Diabetes, 66 p.3122-3129
Journal articleGenetic and environmental interactions modify the risk of diabetes-related autoimmunity by 6 years of age : The teddy study
Jeffrey P. Krischer, Kristian F Lynch, Ake Lernmark, William A Hagopian, Marian J. Rewers, et al.
(2017) Diabetes Care, 40 p.1194-1202
Journal articleJoint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes : results from the TEDDY study
Meike Köhler, Andreas Beyerlein, Kendra Vehik, Sonja Greven, Nikolaus Umlauf, et al.
(2017) Acta Diabetologica, 54 p.1009-1017
Journal articleAntibody Affinity Against 2009 A/H1N1 Influenza and Pandemrix Vaccine Nucleoproteins Differs Between Childhood Narcolepsy Patients and Controls
Alexander Lind, Eva Freyhult, Anita Ramelius, Tomas Olsson, Lisen Arnheim-Dahlström, et al.
(2017) Viral Immunology, 30 p.590-600
Journal articleRespiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity : the TEDDY study
Maria Lönnrot, Kristian F. Lynch, Helena Elding Larsson, Åke Lernmark, Marian J. Rewers, et al.
(2017) Diabetologia, 60 p.1931-1940
Journal articleUnderstanding and preventing type 1 diabetes through the unique working model of TrialNet
Manuela Battaglia, Mark S Anderson, Jane H. Buckner, Susan M. Geyer, Peter A Gottlieb, et al.
(2017) Diabetologia, 60 p.2139-2147
Journal articleDifferent DRB1*03 : 01-DQB1*02:01 haplotypes confer different risk for celiac disease
S. Alshiekh, L. P. Zhao, Lernmark, Daniel E Geraghty, Asa T Naluai, et al.
(2017) HLA: Immune Response Genetics, 90 p.95-101
Journal articleBuilding and validating a prediction model for paediatric type 1 diabetes risk using next generation targeted sequencing of class II HLA genes
Lue Ping Zhao, Annelie Carlsson, Helena Elding Larsson, Gun Forsander, Sten A Ivarsson, et al.
(2017) Diabetes/Metabolism Research and Reviews, 33
Journal articleThe feasibility of salivary sample collection in an international pediatric cohort : The the TEDDY study
Roswith Roth, Judith Baxter, Kendra Vehik, Diane Hopkins, Michael Killian, et al.
(2017) Developmental Psychobiology, 59 p.658-667
Journal articleEarly prediction of autoimmune (type 1) diabetes
Simon E. Regnell, Åke Lernmark
(2017) Diabetologia, 60 p.1370-1381
Journal articleAnalgesic antipyretic use among young children in the TEDDY study : No association with islet autoimmunity
Markus Lundgren, Leigh Johnson Steed, Roy N. Tamura, Berglind Jonsdottir, Patricia Gesualdo, et al.
(2017) BMC Pediatrics, 17
Journal articleType 1 diabetes mellitus
Anastasia Katsarou, Soffia Gudbjörnsdottir, Araz Rawshani, Dana Dabelea, Ezio Bonifacio, et al.
(2017) Nature Reviews Disease Primers, 3
Journal articleMaternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring : The Environmental Determinants of Diabetes in the Young (TEDDY) study
Jimin Yang, Roy N. Tamura, Carin Andrén Aronsson, Ulla M Uusitalo, Åke Lernmark, et al.
(2017) British Journal of Nutrition, 117 p.466-472
Journal articleFirst infant formula type and risk of islet autoimmunity in the environmental determinants of diabetes in the young (TEDDY) study
Sandra Hummel, Andreas Beyerlein, Roy N. Tamura, Ulla Uusitalo, Carin Andŕen Aronsson, et al.
(2017) Diabetes Care, 40 p.398-404
Journal articlePsychological manifestations of celiac disease autoimmunity in young children
Laura B. Smith, Kristian Lynch, Kalle Kurppa, Sibylle Koletzko, Jeffrey Krischer, et al.
(2017) Pediatrics, 139
Journal articleAn Increased Diagnostic Sensitivity of Truncated GAD65 Autoantibodies in Type 1 Diabetes May Be Related to HLA-DQ8
Axel Wester, Hanna Skärstrand, Alexander Lind, Anita Ramelius, Annelie Carlsson, et al.
(2017) Diabetes, 66 p.735-740
Journal articleLongitudinal analysis of hepatic transcriptome and serum metabolome demonstrates altered lipid metabolism following the onset of hyperglycemia in spontaneously diabetic BioBreeding rats
Simon E. Regnell, Martin J Hessner, Shuang Jia, Lina Åkesson, Hans Stenlund, et al.
(2017) PLoS ONE, 12
Journal articleIslet autoantibodies present in association with Ljungan virus infection in bank voles (Myodes glareolus) in northern Sweden
Anna Warvsten, Martin Björnfors, Michael Arvidsson, Fariba Vaziri-Sani, Ida Jönsson, et al.
(2017) Journal of Medical Virology, 89 p.24-31
Journal articleResidual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls
Andrea K Steck, Helena Elding Larsson, Xiang Liu, Riitta Veijola, Jorma Toppari, et al.
(2017) Pediatric Diabetes, 18 p.794-802
Journal articleThyroid and islet autoantibodies predict autoimmune thyroid disease already at Type 1 diabetes diagnosis
Berglind Jonsdottir, Christer Larsson, Annelie Carlsson, Gun Forsander, Sten Anders Ivarsson, et al.
(2017) The Journal of clinical endocrinology and metabolism, 102 p.1277-1285
Journal articleFactors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life
Kaisa M Kemppainen, Kristian F. Lynch, Edwin Liu, Maria Lönnrot, Ville Simell, et al.
(2017) Clinical Gastroenterology and Hepatology, 15 p.5-702
Journal articleIncreased DNA methylation variability in type 1 diabetes across three immune effector cell types
Dirk S. Paul, Andrew E. Teschendorff, Mary A N Dang, Robert Lowe, Mohammed I. Hawa, et al.
(2016) Nature Communications, 7
Journal articleReversion of β-cell autoimmunity changes risk of type 1 diabetes : TEDDY study
Kendra Vehik, Kristian F. Lynch, Desmond A. Schatz, Beena Akolkar, William Hagopian, et al.
(2016) Diabetes Care, 39 p.1535-1542
Journal articleA Comparison of Rule-based Analysis with Regression Methods in Understanding the Risk Factors for Study Withdrawal in a Pediatric Study
Mona Haghighi, Suzanne Bennett Johnson, Xiaoning Qian, Kristian F. Lynch, Kendra Vehik, et al.
(2016) Scientific Reports, 6
Journal articleGrowth and risk for islet autoimmunity and progression to type 1 diabetes in early childhood : The environmental determinants of diabetes in the young study
Helena Elding Larsson, Kendra Vehik, Michael J. Haller, Xiang Liu, Beena Akolkar, et al.
(2016) Diabetes, 65 p.1988-1995
Journal articleEnvironmental factors in the etiology of type 1 diabetes, celiac disease, and narcolepsy
Åke Lernmark
(2016) Pediatric Diabetes, 17 p.65-72
Journal article reviewComplement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study
Carina Törn, Xiang Liu, William Hagopian, Åke Lernmark, Olli Simell, et al.
(2016) Scientific Reports, 6
Journal articleGenetic risk factors for type 1 diabetes
Flemming Pociot, Åke Lernmark
(2016) The Lancet, 387 p.2331-2339
Journal articleAn Object-Oriented Regression for Building Disease Predictive Models with Multiallelic HLA Genes
Lue Ping Zhao, Hamid Bolouri, Michael Zhao, Daniel E. Geraghty, Åke Lernmark
(2016) Genetic Epidemiology, 40 p.315-332
Journal articleType 1 Diabetes
Åke Lernmark, Shehab Alshiekh
(2016) Encyclopedia of immunobiology : Physiology and Immune System Dysfunction, 5 p.159-167
Book chapterType 1 Diabetes
Ake Lernmark, Shehab Abdulaziz Alshiekh
(2016) Encyclopedia of Immunobiology , p.159-167
Book chapterPancreas volume and fat fraction in children with Type 1 diabetes
SIMON ERINGSMARK REGNÉLL, P Peterson, L Trinh, P Broberg, P Leander, et al.
(2016) Diabetic Medicine, 33 p.1374-1379
Journal articleNext generation sequencing reveals that HLA-DRB3, -DRB4 and -DRB5 may be associated with islet autoantibodies and risk for childhood type 1 diabetes.
Lue Ping Zhao, Shehab Alshiekh, Annelie Carlsson, Helena Larsson, Gun Forsander, et al.
(2016) Diabetes, 65 p.710-718
Journal articleDiabetes at the crossroads: relevance of disease classification to pathophysiology and treatment.
R David Leslie, Jerry Palmer, Nanette C Schloot, Åke Lernmark
(2016) Diabetologia, 59 p.13-20
Journal article reviewEffects of Gluten Intake on Risk of Celiac Disease: a case-control study on a Swedish birth cohort.
Carin Andrén Aronsson, Hye-Seung Lee, Sibylle Koletzko, Ulla Uusitalo, Jimin Yang, et al.
(2016) Clinical Gastroenterology and Hepatology, 14 p.403-409
Journal articleAltered regulatory T cell phenotype in latent autoimmune diabetes of the adults (LADA)
M. Radenkovic, C. Silver, J. Arvastsson, K. Lynch, Åke Lernmark, et al.
(2016) Clinical and Experimental Immunology, 186 p.46-56
Journal articleIdentification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort
Ashok Sharma, Xiang Liu, David Hadley, William Hagopian, Edwin Liu, et al.
(2016) PLoS ONE, 11 p.0152476-0152476
Journal articleType 1 (Insulin-Dependent) Diabetes Mellitus : Etiology, Pathogenesis, Prediction, and Prevention
Ahmed J. Delli, Åke Lernmark
(2016) Endocrinology : Adult and Pediatric, 1-2 p.5-690
Book chapterElevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome.
Gucci Jijuan Gu Urban, Mikaela Friedman, Ping Ren, Carina Törn, Malin Fex, et al.
(2015) Scientific Reports, 5
Journal articlePlasma GAD65, a Marker for Early beta-Cell Loss After Intraportal Islet Cell Transplantation in Diabetic Patients
Zhidong Ling, Pieter De Pauw, Daniel Jacobs-Tulleneers-Thevissen, Rui Mao, Pieter Gillard, et al.
(2015) Journal of Clinical Endocrinology and Metabolism, 100 p.2314-2321
Journal articleA method for reporting and classifying acute infectious diseases in a prospective study of young children: TEDDY
Maria Lönnrot, Kristian Lynch, Helena Larsson, Åke Lernmark, Marian Rewers, et al.
(2015) BMC Pediatrics, 15
Journal articlePredictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY).
Andrea K Steck, Kendra Vehik, Ezio Bonifacio, Åke Lernmark, Anette-G Ziegler, et al.
(2015) Diabetes Care, 38 p.808-813
Journal articleRole of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the TEDDY Study.
Carina Törn, David Hadley, Hye-Seung Lee, William Hagopian, Åke Lernmark, et al.
(2015) Diabetes, 64 p.1818-1829
Journal articleStaging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association.
Richard A Insel, Jessica L Dunne, Mark A Atkinson, Jane L Chiang, Dana Dabelea, et al.
(2015) Diabetes Care, 38 p.1964-1974
Journal articleSerological evaluation of possible exposure to Ljungan virus and related parechovirus in autoimmune (type 1) diabetes in children.
Anna-Lena Nilsson, Fariba Vaziri Sani, Per Broberg, A Elfaitouri, R Pipkorn, et al.
(2015) Journal of Medical Virology, 87 p.1130-1140
Journal articleDetermination of 21-hydroxylase autoantibodies: inter-laboratory concordance in the Euradrenal International Serum Exchange Program
Alberto Falorni, Vittorio Bini, Corrado Betterle, Annalisa Brozzetti, Luis Castano, et al.
(2015) Clinical Chemistry and Laboratory Medicine, 53 p.1761-1770
Journal articleMagnetic resonance imaging reveals altered distribution of hepatic fat in children with type 1 diabetes compared to controls.
Simon Regnell, Pernilla Peterson, Lena Trinh, Per Broberg, Peter Leander, et al.
(2015) Metabolism, Clinical and Experimental, 64 p.872-878
Journal articleZnT8 autoantibody epitope specificity and affinity examined with recombinant ZnT8 variant proteins in specific ZnT8R and ZnT8W autoantibody positive type 1 diabetes patients.
Hanna Skärstrand, Ewa Krupinska, Tatu Haataja, Fariba Vaziri Sani, Jens Lagerstedt, et al.
(2015) Clinical and Experimental Immunology, 179 p.220-229
Journal articleThe streetlight effect-is there light at the end of the tunnel?
Åke Lernmark
(2015) Diabetes, 64 p.1105-1107
Journal article (comment)Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: results from the TEDDY study.
Andreas Beyerlein, Xiang Liu, Ulla M Uusitalo, Minna Harsunen, Jill M Norris, et al.
(2015) American Journal of Clinical Nutrition, 102 p.345-352
Journal articleEarly Childhood Gut Microbiomes Show Strong Geographic Differences Among Subjects at High Risk for Type 1 Diabetes.
Kaisa M Kemppainen, Alexandria N Ardissone, Austin G Davis-Richardson, Jennie R Fagen, Kelsey A Gano, et al.
(2015) Diabetes Care, 38 p.329-332
Journal articlePrevalence of celiac disease autoimmunity in children with type 1 diabetes: regional variations across the Øresund strait between Denmark and southernmost Sweden.
Emma Adlercreutz, Jannet Svensson, Dorthe Hansen, Karsten Buschard, Åke Lernmark, et al.
(2015) Pediatric Diabetes, 16 p.504-509
Journal articleDoubly reactive INS-IGF2 autoantibodies in children with newly diagnosed autoimmune (type 1) diabetes.
Norio Kanatsuna, Ahmed Delli, Cecilia K Andersson, Anna-Lena Nilsson, Fariba Vaziri Sani, et al.
(2015) Scandinavian Journal of Immunology, 82 p.361-369
Journal articleBaseline heterogeneity in glucose metabolism marks the risk for type 1 diabetes and complicates secondary prevention.
Helena Larsson, Christer Larsson, Åke Lernmark
(2015) Acta Diabetologica, 52 p.473-481
Journal articleNeuropeptide Y is a minor autoantigen in newly diagnosed type 1 diabetes patients.
Hanna Skärstrand, Fariba Vaziri Sani, Ahmed Delli, Carina Törn, Helena Larsson, et al.
(2015) Pediatric Diabetes, 16 p.621-628
Journal articleA Functional Polymorphism of Ptpn22 Is Associated with Type 1 Diabetes in the BioBreeding Rat.
Janice Sarmiento, Robert H Wallis, Terri Ning, Leili Marandi, Gary Chao, et al.
(2015) Journal of Immunology, 194 p.615-629
Journal articleNon-HLA type 1 diabetes genes modulate disease risk together with HLA-DQ and islet autoantibodies.
M Maziarz, W Hagopian, J P Palmer, C B Sanjeevi, I Kockum, et al.
(2015) Genes and Immunity, 16 p.541-551
Journal articleThe 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study
Jeffrey P. Krischer, Kristian F. Lynch, Desmond A. Schatz, Jorma Ilonen, Åke Lernmark, et al.
(2015) Diabetologia, 58 p.980-987
Journal articleFactors associated with longitudinal food record compliance in a paediatric cohort study.
Jimin Yang, Kristian F Lynch, Ulla M Uusitalo, Kristina Foterek, Sandra Hummel, et al.
(2015) Public Health Nutrition , p.1-10
Journal articleAssociation of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study.
Ulla Uusitalo, Xiang Liu, Jimin Yang, Carin Andrén Aronsson, Sandra Hummel, et al.
(2015) JAMA Pediatrics, 170 p.20-28
Journal articleImmunology of β-Cell Destruction
Åke Lernmark, DARIA LA TORRE, MARKUS LUNDGREN, Helena Larsson
(2015) Islets of Langerhans , p.1047-1080
Book chapterCell-surface MHC density profiling reveals instability of autoimmunity-associated HLA
Hiroko Miyadera, Jun Ohashi, Åke Lernmark, Toshio Kitamura, Katsushi Tokunaga
(2015) Journal of Clinical Investigation, 125 p.275-291
Journal articleGAD Autoantibody Affinity in Adult Patients With Latent Autoimmune Diabetes, the Study Participants of a GAD65 Vaccination Trial
Stephanie Krause, Ulrike Landherr, Carl-David Agardh, Simone Hausmann, Katarina Link, et al.
(2014) Diabetes Care, 37 p.1675-1680
Journal articleHigh plasma levels of islet amyloid polypeptide in young with new-onset of type 1 diabetes mellitus.
Johan F Paulsson, Johnny Ludvigsson, Annelie Carlsson, Rosaura Casas, Gun Forsander, et al.
(2014) PLoS ONE, 9
Journal articleLack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus.
Kerstin M Ahlgren, Tove Fall, Nils Landegren, Lars Grimelius, Henrik von Euler, et al.
(2014) PLoS ONE, 9
Journal articleIslet cell antibodies (ICA) identify autoimmunity in children with new onset diabetes mellitus negative for other islet cell antibodies.
Cecilia K Andersson, Martin Kolmodin, Sten Ivarsson, Annelie Carlsson, Gun Forsander, et al.
(2014) Pediatric Diabetes, 15 p.336-344
Journal articleChildren followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease.
Helena Larsson, Kendra Vehik, Patricia Gesualdo, Beena Akolkar, William Hagopian, et al.
(2014) Pediatric Diabetes, 15 p.118-126
Journal articleActivating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease.
Sarah E Flanagan, Emma Haapaniemi, Mark A Russell, Richard Caswell, Hana Lango Allen, et al.
(2014) Nature Genetics, 46 p.812-814
Journal articlePrevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes.
J Yang, Åke Lernmark, U M Uusitalo, K F Lynch, R Veijola, et al.
(2014) International Journal of Obesity, 38 p.1491-1496
Journal articleVariability in the CIITA gene interacts with HLA in multiple sclerosis.
A Gyllenberg, F Piehl, L Alfredsson, J Hillert, I L Bomfim, et al.
(2014) Genes and Immunity, 15 p.162-167
Journal articleA/H1N1 antibodies and TRIB2 autoantibodies in narcolepsy patients diagnosed in conjunction with the Pandemrix vaccination campaign in Sweden 2009-2010.
Alexander Lind, Anita Ramelius, Tomas Olsson, Lisen Arnheim-Dahlström, Favelle Lamb, et al.
(2014) Journal of Autoimmunity, 50 p.99-106
Journal articleAntibodies to influenza virus A/H1N1 hemagglutinin in type 1 diabetes children diagnosed before, during and after the Swedish A(H1N1)pdm09 vaccination campaign 2009-2010.
Matilda1 Svensson, Anita Ramelius, Anna-Lena Nilsson, Ahmed Delli, Helena Larsson, et al.
(2014) Scandinavian Journal of Immunology, 79 p.137-148
Journal articleBiomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study
Hye-Seung Lee, Brant R. Burkhardt, Wendy McLeod, Susan Smith, Chris Eberhard, et al.
(2014) Diabetes/Metabolism Research & Reviews, 30 p.424-434
Journal articleReduced morbidity at diagnosis and improved glycemic control in children previously enrolled in DiPiS follow-up
Markus Lundgren, Åsa Sahlin, Camilla Svensson, Annelie Carlsson, Elisabeth Cedervall, et al.
(2014) Pediatric Diabetes, 15 p.494-501
Journal articleType 1 (Insulin-Dependent) Diabetes Mellitus
Ahmed Delli, Åke Lernmark
(2014) Endocrinology: Adult and Pediatric , p.671-691
Book chapterCarl-David Agardh, 1946-2013.
Leif Groop, Åke Lernmark, Jan Nilsson
(2014) Diabetologia
Journal articleRelationship Between Ljungan Virus Antibodies, HLA-DQ8, and Insulin Autoantibodies in Newly Diagnosed Type 1 Diabetes Children
Anna-Lena Nilsson, Fariba Vaziri Sani, Cecilia K Andersson, Karin Larsson, Annelie Carlsson, et al.
(2013) Viral Immunology, 26 p.207-215
Journal articleDecline in Titers of Anti-Idiotypic Antibodies Specific to Autoantibodies to GAD65 (GAD65Ab) Precedes Development of GAD65Ab and Type 1 Diabetes.
Helena Larsson, Ida Jönsson, Åke Lernmark, Sten Ivarsson, Jared R Radtke, et al.
(2013) PLoS ONE, 8
Journal articleImmune therapy in type 1 diabetes mellitus.
Åke Lernmark, Helena Larsson
(2013) Nature Reviews Endocrinology, 9 p.92-103
Journal articleMethods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY
Kendra Vehik, Steven W. Fiske, Chad A. Logan, Daniel Agardh, Corrado Cilio, et al.
(2013) Diabetes/Metabolism Research & Reviews, 29 p.557-567
Journal articleNext-generation sequencing for viruses in children with rapid-onset type 1 diabetes
H-S Lee, T. Briese, C. Winkler, M. Rewers, E. Bonifacio, et al.
(2013) Diabetologia, 56 p.1705-1711
Journal articleDepleting T cells in newly diagnosed autoimmune (type 1) diabetes--are we getting anywhere?
Åke Lernmark
(2013) Diabetes, 62 p.3669-3670
Journal article (comment)Triple specificity of ZnT8 autoantibodies in relation to HLA and other islet autoantibodies in childhood and adolescent type 1 diabetes.
C Andersson, Fariba Vaziri Sani, Aj Delli, Bengt Lindblad, Annelie Carlsson, et al.
(2013) Pediatric Diabetes, 14 p.97-105
Journal articleBiobreeding rat islets exhibit reduced antioxidative defense and N-acetyl cysteine treatment delays type 1 diabetes
Marika Bogdani, Angela M. Henschel, Sanjay Kansra, Jessica M. Fuller, Rhonda Geoffrey, et al.
(2013) Journal of Endocrinology, 216 p.111-123
Journal articleGlucose tolerance and beta-cell function in islet autoantibody-positive children recruited to a secondary prevention study.
Cecilia K Andersson, Annelie Carlsson, Corrado Cilio, Elisabeth Cedervall, Sten Ivarsson, et al.
(2013) Pediatric Diabetes, 14 p.341-349
Journal articleDecreased cord-blood phospholipids in young age at onset type 1 diabetes.
Daria La Torre, Tulikki Seppänen-Laakso, Helena Larsson, Tuulia Hyötyläinen, Sten Ivarsson, et al.
(2013) Diabetes, 62 p.3951-3956
Journal articleDecline of C-peptide during the first year after diagnosis of Type 1 diabetes in children and adolescents
Johnny Ludvigsson, Annelie Carlsson, Ahmed Deli, Gun Forsander, Sten Ivarsson, et al.
(2013) Diabetes Research and Clinical Practice, 100 p.203-209
Journal articleAutoimmunity against INS-IGF2 expressed in human pancreatic islets.
Norio Kanatsuna, Jalal Taneera, Fariba Vaziri Sani, Nils Wierup, Helena Larsson, et al.
(2013) Journal of Biological Chemistry, 288 p.29013-29023
Journal articleIs there evidence for post-translational modification of beta cell autoantigens in the aetiology and pathogenesis of type 1 diabetes?
Åke Lernmark
(2013) Diabetologia, 56 p.2355-2358
Journal articleNeuropeptide Y autoantibodies in patients with long-term type 1 and type 2 diabetes and neuropathy.
Hanna Skärstrand, L B Dahlin, Åke Lernmark, Fariba Vaziri Sani
(2013) Journal of Diabetes and its Complications, 27 p.609-617
Journal articleResidual beta cell function at diagnosis of type 1 diabetes in children and adolescents varies with gender and season
U. Samuelsson, B. Lindblad, Annelie Carlsson, G. Forsander, Sten Ivarsson, et al.
(2013) Diabetes/Metabolism Research & Reviews, 29 p.85-89
Journal articleThyroid autoimmunity in relation to islet autoantibodies and HLA-DQ genotype in newly diagnosed type 1 diabetes in children and adolescents.
Berglind Jonsdottir, Cecilia K Andersson, Annelie Carlsson, Ahmed Delli, G Forsander, et al.
(2013) Diabetologia, 56 p.1735-1742
Journal articleAutoimmune (type 1) diabetes
Ahmed Delli, Åke Lernmark
(2013) The Autoimmune Diseases , p.575-585
Book chapterMeta-Immunological Profiling of Children With Type 1 Diabetes Identifies New Biomarkers to Monitor Disease Progression
Mario Galgani, Rosa Nugnes, Dario Bruzzese, Francesco Perna, Veronica De Rosa, et al.
(2013) Diabetes, 62 p.2481-2491
Journal articleViruses, diabetes, and autoimmunity : Studies of subjects at genetic risk for type 1 diabetes
Sabina Resic Lindehammer, Åke Lernmark
(2013) Diabetes and Viruses, 9781461440512 p.187-194
Book chapterThe environment and the origins of islet autoimmunity and Type 1 diabetes.
S Eringsmark Regnéll, Åke Lernmark
(2012) Diabetic medicine : a journal of the British Diabetic Association
Journal articleAntigenicity and epitope specificity of ZnT8 autoantibodies in type 1 diabetes.
Hanna Skärstrand, Åke Lernmark, Fariba Vaziri Sani
(2012) Scandinavian Journal of Immunology
Journal articleSeroconversion to Islet Autoantibodies After Enterovirus Infection in Early Pregnancy.
Sabina Rešić Lindehammer, Hanna Honkanen, William Allan Nix, Maarit Oikarinen, Kristian Lynch, et al.
(2012) Viral Immunology, 25 p.254-261
Journal articleHTR1A a Novel Type 1 Diabetes Susceptibility Gene on Chromosome 5p13-q13
Samina Asad, Pernilla Nikamo, Alexandra Gyllenberg, Hedvig Bennet, Ola Hansson, et al.
(2012) PLoS ONE, 7
Journal articleZinc Transporter 8 Autoantibodies and Their Association With SLC30A8 and HLA-DQ Genes Differ Between Immigrant and Swedish Patients With Newly Diagnosed Type 1 Diabetes in the Better Diabetes Diagnosis Study.
Ahmed Delli, Fariba Vaziri Sani, Bengt Lindblad, Helena Larsson, Annelie Carlsson, et al.
(2012) Diabetes, 61 p.2556-2564
Journal articleGuías y recomendaciones para el diagnóstico y manejo de la Diabetes Mellitus
David B. Sacks, Mark Arnold, George L. Bakris, David E. Bruns, Andrea Rita Horvath, et al.
(2012) Acta Bioquimica Clinica Latinoamericana, 46 p.303-336
Journal articleBLUEPRINT to decode the epigenetic signature written in blood
David Adams, Lucia Altucci, Stylianos E. Antonarakis, Juan Ballesteros, Stephan Beck, et al.
(2012) Nature Biotechnology, 30 p.224-226
Journal article (letter)High levels of immunoglobulin E and a continuous increase in immunoglobulin G and immunoglobulin M by age in children with newly diagnosed type 1 diabetes
Jannet Svensson, Stefanie Eising, Henrik Bindesbol Mortensen, Michael Christiansen, Inga Laursen, et al.
(2012) Human Immunology, 73 p.17-25
Journal articleIslet autoantibodies and residual beta cell function in type 1 diabetes children followed for 3-6 years
J. S. Sorensen, Fariba Vaziri Sani, M. Maziarz, K. Kristensen, A. Ellerman, et al.
(2012) Diabetes Research and Clinical Practice, 96 p.204-210
Journal articleFew differences in cytokines between patients newly diagnosed with type 1 diabetes and their healthy siblings
Jannet Svensson, Stefanie Eising, David Michael Hougaard, Henrik Bindesbol Mortensen, Kristin Skogstrand, et al.
(2012) Human Immunology, 73 p.1116-1126
Journal articleAssociation between autoantibodies to the Arginine variant of the Zinc transporter 8 (ZnT8) and stimulated C-peptide levels in Danish children and adolescents with newly diagnosed type 1 diabetes
Marie Louise M. Andersen, Fariba Vaziri Sani, Ahmed Delli, Sven Porksen, Emma Jacobssen, et al.
(2012) Pediatric Diabetes, 13 p.454-462
Journal articleAge-dependent variation of genotypes in MHC II transactivator gene (CIITA) in controls and association to type 1 diabetes
A Gyllenberg, Samina Asad, F Piehl, Maria Swanberg, L Padyukov, et al.
(2012) Genes and Immunity, 13 p.632-640
Journal articleC-peptide in the classification of diabetes in children and adolescents.
Johnny Ludvigsson, Annelie Carlsson, G Forsander, Sten Ivarsson, I Kockum, et al.
(2012) Pediatric Diabetes, 13 p.45-50
Journal articleHLA-DQB1 genotypes and islet cell autoantibodies against GAD65 and IA-2 in relation to development of diabetes post partum in women with gestational diabetes mellitus.
Anastasia Papadopoulou, Kristian Lynch, Eva Anderberg, Mona Landin-Olsson, Ida Jönsson, et al.
(2012) Diabetes Research and Clinical Practice, 95 p.260-264
Journal articleLow risk HLA-DQ and increased body mass index in newly diagnosed type 1 diabetes children in the Better Diabetes Diagnosis study in Sweden.
Annelie Carlsson, I Kockum, Bengt Lindblad, Lisa Engleson, A Nilsson, et al.
(2012) International Journal of Obesity, 36 p.718-724
Journal articleGuthrie card methylomics identifies temporally stable epialleles that are present at birth in humans
Huriya Beyan, Thomas A. Down, Sreeram V. Ramagopalan, Kristina Uvebrant, Anita Ramelius, et al.
(2012) Genome Research, 22 p.2138-2145
Journal articleDETECTION OF LACTOBACILLI IN MONTHLY MAIL-IN STOOL SAMPLES FROM 3-18 MONTHS OLD INFANTS AT GENETIC RISK FOR TYPE 1 DIABETES
F Salami, M Abels, H Hyöty, F Vaziri-Sani, Carin Andrén Aronsson, et al.
(2012) International journal of probiotics & prebiotics, 7 p.135-144
Journal articleCRYAB-650 C>G (rs2234702) affects susceptibility to Type 1 diabetes and IAA-positivity in Swedish population
Chengjun Sun, Åke Lernmark, Mona Landin-Olsson, Bengt Scherstén, Sten-A Ivarsson, et al.
(2012) Human Immunology, 73 p.759-766
Journal articleSustained glucagon-like peptide 1 expression from encapsulated transduced cells to treat obese diabetic rats
Daniel H. Moralejo, Ofer Yanay, Kelly Kernan, Adam Bailey, Ake Lernmark, et al.
(2011) Journal of Bioscience and Bioengineering, 111 p.383-387
Journal articleDoes immune-tolerance treatment with Alum-formulated GAD65 protect insulin-production in the pancreatic islet β cells?
Helena Elding Larsson, Åke Lernmark
(2011) Human Vaccines, 7 p.45-49
Journal article reviewPosition Statement Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus
David B. Sacks, Mark Arnold, George L. Bakris, David E. Bruns, Andrea Rita Horvath, et al.
(2011) Diabetes Care, 34 p.1419-1423
Journal articleHLA Genes, Islet Autoantibodies and Residual C-Peptide at the Clinical Onset of Type 1 Diabetes Mellitus and the Risk of Retinopathy 15 Years Later
Richard A. Jensen, Elisabet Agardh, Åke Lernmark, Soffia Gudbjornsdottir, Nicholas L. Smith, et al.
(2011) PLoS ONE, 6
Journal articleThe three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes.
Cecilia K Andersson, Karin Larsson, Fariba Vaziri Sani, Kristian Lynch, Annelie Carlsson, et al.
(2011) Autoimmunity, 44 p.394-405
Journal articleGestational diabetes mellitus is associated with TCF7L2 gene polymorphisms independent of HLA-DQB1*0602 genotypes and islet cell autoantibodies.
Anastasia Papadopoulou, Kristian Lynch, Nael Shaat, Rasmus Bennet, Sten Ivarsson, et al.
(2011) Diabetic Medicine, 28 p.1018-1027
Journal articleCorrelations between islet autoantibody specificity and the SLC30A8 genotype with HLA-DQB1 and metabolic control in new onset type 1 diabetes
Caroline Brorsson, Fariba Vaziri Sani, Regine Bergholdt, Stefanie Eising, Anita Ramelius, et al.
(2011) Autoimmunity, 44 p.107-114
Journal articleRelationship between ZnT8Ab, the SLC30A8 gene and disease progression in children with newly diagnosed type 1 diabetes
Lotte B. Nielsen, Fariba Vaziri Sani, Sven Poerksen, Marie-Louise M. Andersen, Jannet Svensson, et al.
(2011) Autoimmunity, 44 p.616-623
Journal articleCountry-specific birth weight and length in type 1 diabetes high-risk HLA genotypes in combination with prenatal characteristics.
Y Sterner, Carina Törn, H-S Lee, Helena Larsson, Christian Winkler, et al.
(2011) Journal of Perinatology, 31 p.764-769
Journal articleBB rat Gimap gene expression in sorted lymphoid T and B cells
Daniel H. Moralejo, Jessica Fuller, Elizabeth A. Rutledge, Brian Van Yserloo, Ruth A. Ettinger, et al.
(2011) Life Sciences, 89 p.748-754
Journal articleExecutive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus
David B. Sacks, Mark Arnold, George L. Bakris, David E. Bruns, Andrea Rita Horvath, et al.
(2011) Clinical Chemistry, 57 p.793-798
Journal article (comment)Seroconversion to islet autoantibodies between early pregnancy and delivery in non-diabetic mothers
Sabina Lindehammer, Ida Jönsson, Bo Midberg, Sten Ivarsson, Kristian Lynch, et al.
(2011) Journal of Reproductive Immunology, 88 p.72-79
Journal articleDanish children born with glutamic acid decarboxylase-65 and islet antigen-2 autoantibodies at birth had an increased risk to develop type 1 diabetes
Stefanie Eising, Anita Ramelius, Bendix Carstensen, David M. Hougaard, Bent Norgaard-Pedersen, et al.
(2011) European Journal of Endocrinology, 164 p.247-252
Journal articleGuidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus
David B. Sacks, Mark Arnold, George L. Bakris, David E. Bruns, Andrea Rita Horvath, et al.
(2011) Clinical Chemistry, 57 p.1-47
Journal articleSerum metabolite signature predicts the acute onset of diabetes in spontaneously diabetic congenic BB rats
Lina Åkesson, Johan Trygg, Jessica Fuller, Rasmus Madsen, Jon Gabrielsson, et al.
(2011) Metabolomics, 7 p.593-603
Journal articleEarly-Pregnancy Cytokines in Mothers to Children Developing Multiple, Persistent Islet Autoantibodies, Type 1 Diabetes, or Both Before 7 Years of Age.
Sabina Lindehammer, Malin Fex, Marlena Maziarz, Ida Hanson, Karel Marsal, et al.
(2011) American Journal of Reproductive Immunology, 66 p.495-503
Journal articleEditorial Comment on type 1 diabetes and antigen-specific immunotherapy.
Åke Lernmark, H E Larsson
(2011) Journal of Internal Medicine, 270 p.132-135
Journal article (letter)Vaccination against type 1 diabetes.
Helena Elding Larsson, Åke Lernmark
(2011) Journal of Internal Medicine, 269 p.626-635
Journal articleHigh-titer GAD65 autoantibodies detected in adult diabetes patients using a high efficiency expression vector and cold GAD65 displacement.
Ida Jönsson, Kristian Lynch, Göran Hallmans, Åke Lernmark, Olov Rolandsson
(2011) Autoimmunity, 44 p.129-136
Journal articleA novel triple mix radiobinding assay for the three ZnT8 (ZnT8-RWQ) autoantibody variants in children with newly diagnosed diabetes.
Fariba Vaziri Sani, Ahmed Delli, Helena Larsson, Bengt Lindblad, Annelie Carlsson, et al.
(2011) Journal of Immunological Methods, 371 p.25-37
Journal articleHepatic steatosis in type 1 diabetes
Simon Regnell, Åke Lernmark
(2011) Review of Diabetic Studies, 8 p.454-467
Journal article reviewThe Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants.
William A Hagopian, Henry Erlich, Åke Lernmark, Marian Rewers, Anette G Ziegler, et al.
(2011) Pediatric Diabetes, 12 p.733-743
Journal articleIncreased GABA(A) channel subunits expression in CD8(+) but not in CD4(+) T cells in BB rats developing diabetes compared to their congenic littermates
Suresh Kumar Mendu, Lina Åkesson, Zhe Jin, Anna Edlund, Corrado Cilio, et al.
(2011) Molecular Immunology, 48 p.399-407
Journal articleGuidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus
David B. Sacks, Mark Arnold, George L. Bakris, David E. Bruns, Andrea Rita Horvath, et al.
(2011) Diabetes Care, 34 p.61-99
Journal article reviewComparison of Radioimmunoprecipitation With Luciferase Immunoprecipitation for Autoantibodies to GAD65 and IA-2 beta
Peter D. Burbelo, Hiroki Hirai, Alexandra T. Issa, Albert Kingman, Åke Lernmark, et al.
(2010) Diabetes Care, 33 p.754-756
Journal articleA distinct metabolic profile at birth identifies children developing type 1 diabetes before 20 years of age
Daria La Torre, Åke Lernmark, Peter Spégel, H. Elding Larsson, Sten Ivarsson, et al.
(2010) Diabetologia, 53 p.261-261
Conference paper: abstractImmunologic markers at the clinical onset of type 1 diabetes mellitus and the risk of retinopathy 15 years later
R. A. Jensen, Elisabet Agardh, Åke Lernmark, N. L. Smith, D. S. Siscovick, et al.
(2010) Diabetologia, 53 p.155-155
Conference paper: abstractFirst trimester cytokine levels in mothers to children diagnosed with islet autoimmunity or type 1 diabetes before eight years of age
Sabina Lindehammer, Malin Fex, Karel Marsal, Åke Lernmark
(2010) Diabetologia, 53 p.343-343
Conference paper: abstractNovel triples mix radio binding assay for the ZnT8 (ZnT8RWQ) autoantibody variants in children with newly diagnosed diabetes
Fariba Vaziri Sani, Ahmed Delli, Helena Larsson, B Lindblad, Annelie Carlsson, et al.
(2010) Diabetologia, 53 p.264-264
Conference paper: abstractContext and disease when disease risk is low: the case of type 1 diabetes in Sweden
Kristian Lynch, S. V. Subramanian, Henrik Ohlsson, Basile Chaix, Åke Lernmark, et al.
(2010) Journal of Epidemiology and Community Health, 64 p.789-795
Journal articleClinical and genetical characterisation of a series of patients with type 1 diabetes induced by interferon therapy
Ahmed Delli, Fariba Vaziri Sani, Annelie Carlsson, G. Forsander, Sten Ivarsson, et al.
(2010) Diabetologia, 53 p.273-273
Conference paper: abstractStimulation of 5-HT1a receptor decreased insulin secretion in islets of Langerhans from mice and humans
Hedvig Bennet, Cecilia Nagorny, Nils Wierup, Marloes Dekker Nitert, Åke Lernmark, et al.
(2010) Diabetologia, 53 p.547-547
Conference paper: abstractThe association between the PTPN22 1858C > T variant and type 1 diabetes depends on HLA risk and GAD65 autoantibodies
M. Maziarz, M. Janer, J. C. Roach, W. Hagopian, J. P. Palmer, et al.
(2010) Genes and Immunity, 11 p.406-415
Journal articleType 1 diabetes patients born to immigrants to Sweden increase their native diabetes risk and differ from Swedish patients in HLA types and islet autoantibodies.
Ahmed Delli, Bengt Lindblad, Annelie Carlsson, Gun Forsander, Sten Ivarsson, et al.
(2010) Pediatric Diabetes, Apr 8 p.513-520
Journal articleZnT8 autoantibody titers in type 1 diabetes patients decline rapidly after clinical onset.
Fariba Vaziri Sani, Shilpa Oak, Jared Radtke, Åke Lernmark, Kristian Lynch, et al.
(2010) Autoimmunity, Apr 7 p.598-606
Journal articleChanges in GAD65Ab-Specific Antiidiotypic Antibody Levels Correlate with Changes in C-Peptide Levels and Progression to Islet Cell Autoimmunity.
E Ortqvist, B Brooks-Worrell, Kristian Lynch, J Radtke, L M Bekris, et al.
(2010) The Journal of clinical endocrinology and metabolism, 95 p.310-318
Journal articleImmunology of beta-Cell Destruction.
Daria La Torre, Åke Lernmark
(2010) Advances in Experimental Medicine and Biology, 654 p.537-583
Journal articleAutoimmune type 1 diabetes.
Ahmed Delli, Helena Larsson, Sten Ivarsson, Åke Lernmark
(2010) Textbook of Diabetes , p.141-152
Book chapterType 1 (Insulin-Dependent) Diabetes Mellitus: Etiology, Pathogenesis, Prediction and Prevention.
Ahmed Delli, Åke Lernmark
(2010) Textbook of Endocrinology, adult and children 6th ed, Volume 1 p.744-764
Book chapterFuture drug treatment of Type 1 diabetes
Helena Larsson, Ahmed Delli, Sten Ivarsson, Åke Lernmark
(2010) Textbook of Diabetes , p.1001-1016
Book chapterAltered natural killer (NK) cell frequency and phenotype in latent autoimmune diabetes in adults (LADA) prior to insulin deficiency.
Christina Silver, K Uvebrant, Cecilia Oderup, Kristian Lynch, R A Harris, et al.
(2010) Clinical and Experimental Immunology, May 4 p.48-56
Journal articleIdentification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat
Mary L. Kaldunski, Shuang Jia, Rhonda Geoffrey, Joel Basken, Simon Prosser, et al.
(2010) Diabetes, 59 p.2375-2385
Journal articleDifferential effects of leptin receptor mutation on male and female BBDR.Gimap5-/Gimap5- spontaneously diabetic rats
Daniel H. Moralejo, Carl T. Hansen, Piper Treuting, Martin J Hessner, Jessica M. Fuller, et al.
(2010) Physiological Genomics, 41 p.9-20
Journal articleProlonged survival and improved glycemia in BioBreeding diabetic rats after early sustained exposure to glucagon-like peptide
Ofer Yanay, Daniel H. Moralejo, Kelly Kernan, Margaret Brzezinski, Jessica M. Fuller, et al.
(2010) Journal of Gene Medicine, 12 p.538-544
Journal articleSequence Variation and Expression of the Gimap Gene Family in the BB Rat
Elizabeth A. Rutledge, Jessica Fuller, Brian Van Yserloo, Daniel H. Moralejo, Ruth A. Ettinger, et al.
(2009) Experimental Diabetes Research
Journal articleAnalysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus
John P. Mordes, Laura Cort, Elaine Norowski, Jean Leif, Jessica Fuller, et al.
(2009) Mammalian Genome, 20 p.162-169
Journal articleThe non-inherited maternal HLA haplotype affects the risk for type 1 diabetes
Kristina Åkesson, Annelie Carlsson, S. -A. Ivarsson, C. Johansson, B. -M. Weidby, et al.
(2009) International Journal of Immunogenetics, 36 p.1-8
Journal articleComparison of three assays for the detection of GAD65Ab-specific anti-idiotypic antibodies
Shilpa Oak, Jared Radtke, Mona Landin-Olsson, Carina Törn, Åke Lernmark, et al.
(2009) Journal of Immunological Methods, 351 p.55-61
Journal articleLow agreement between radio binding assays in analyzing glutamic acid decarboxylase (GAD65Ab) autoantibodies in patients classified with type 2 diabetes
Bledar Daka, Maria K. Svensson, Åke Lernmark, Lucia Mincheva-Nilsson, Goran Hallmans, et al.
(2009) Autoimmunity, 42 p.507-514
Journal articleTemporal Variation of Ljungan Virus Antibody Levels in Relation to Islet Autoantibodies and Possible Correlation to Childhood Type 1 Diabetes
Anna-Lena Nilsson, Eliza Lagerquist, Kristian Lynch, Åke Lernmark, Rolandsson Olov
(2009) Open Pediatric Medicine Journal, 3 p.61-66
Journal articleGenetic Dissection Reveals Diabetes Loci Proximal to the Gimap5 Lymphopenia Gene.
Jessica Fuller, Marika Bogdani, Terry D Tupling, Richard A Jensen, Ranae Pefley, et al.
(2009) Physiological Genomics, 38 p.89-97
Journal articleThe type 1 diabetes protective HLA DQB1*0602 allele is less frequent in gestational diabetes mellitus.
Anastasia Papadopoulou, Kristian Lynch, Nael Shaat, Anita Nilsson, Barbro Lernmark, et al.
(2009) Diabetologia, 52 p.1339-1342
Journal articleGAD65 vaccination: 5 years of follow-up in a randomised dose-escalating study in adult-onset autoimmune diabetes.
Carl-David Agardh, Kristian Lynch, M Palmér, Katarina Link, Åke Lernmark
(2009) Diabetologia, 52 p.1363-1368
Journal articleStrong association between SLC30A8 gene variant and ZnT8 autoantibody specificity during disease progression in two independent cohorts of children with newly diagnosed type 1 diabetes
L. B. Nielsen, Fariba Vaziri Sani, M-L. M. Andersen, S. Porksen, J. Svensson, et al.
(2009) Diabetologia, 52 p.29-29
Conference paper: abstractRisk Conferred by HLA-DR and DQ for Type 1 Diabetes in 0-35-Year Age Group in Sweden
Carani B. Sanjeevi, Saikiran K Sedimbi, Mona Landin-Olsson, Ingrid Kockum, Åke Lernmark
(2008) Immunology of Diabetes V: From Bench to Bedside, 1150 p.106-111
Conference paperA new luminescence assay for autoantibodies to mammalian cell-prepared insulinoma-associated protein 2
Peter D. Burbelo, Hiroki Hirai, Hannah Leahy, Ake Lernmark, Sten Ivarsson, et al.
(2008) Diabetes Care, 31 p.1824-1826
Journal articleGAD65 Autoimmunity-Clinical Studies
Raivo Uibo, Åke Lernmark
(2008) Advances in Immunology, 100 p.39-78
Journal article reviewCutaneous microvascular dysfunction is associated with diabetes-risk HLA in youths with type 1 diabetes
Michal Odermarsky, Åke Lernmark, Petru Liuba
(2008) Journal of the American College of Cardiology, 51 p.345-345
Conference paper: abstractDecreasing humoral activity in siblings of type 1 diabetes children over a ten year period with increasing incidence of the disease
J. Svensson, Anita Ramelius, S. Eising, H. Mortensen, Åke Lernmark, et al.
(2008) Diabetologia, 51 p.232-233
Conference paper: abstractCutaneous Microvascular Dysfunction Is Associated With Human Leukocyte Antigen-DQ in Youths With Type 1 Diabetes.
Michal Odermarsky, Åke Lernmark, Lennart Truedsson, Petru Liuba
(2008) Pediatric Research, 63 p.420-422
Journal articleSelective screening of secretory vesicle-associated proteins for autoantigens in type 1 diabetes: VAMP2 and NPY are new minor autoantigens
Hiroki Hirai, Junnosuke Miura, Yafang Hu, Helena Larsson, Karin Larsson, et al.
(2008) Clinical Immunology, 127 p.366-374
Journal articleNumber of islet autoantibodies present in newly diagnosed type 1 diabetes children born to non-diabetic mothers is affected by islet autoantibodies present at birth.
Maria Elfving, Bengt Lindberg, Kristian Lynch, Majvi Månsson, Göran Sundkvist, et al.
(2008) Pediatric Diabetes, 9 p.127-134
Journal articleA comparison of serum and EDTA plasma in the measurement of glutamic acid decarboxylase autoantibodies (GADA) and autoantibodies to islet antigen-2 (IA-2A) using the RSR radioimmunoassay (RIA) and enzyme linked immunosorbent assay (ELISA) kits.
Kobra Rahmati, Åke Lernmark, Charlotte Becker, Anna Foltyn Zadura, Karin Larsson, et al.
(2008) Clinical Laboratory, 54 p.227-235
Journal articleMaternal enterovirus infection during pregnancy as a risk factor in offspring diagnosed with type 1 diabetes between 15 and 30 years of age.
Maria Elfving, Johan Svensson, Sami Oikarinen, Björn Jonsson, Per Olofsson, et al.
(2008) Experimental Diabetes Research, 2008
Journal articleTemporal trends of HLA genotype frequencies of type 1 diabetes patients in Sweden from 1986 to 2005 suggest altered risk.
Sabina Lindehammer, Karin Larsson, Eva Örtqvist, Annelie Carlsson, E Cederwall, et al.
(2008) Acta Diabetologica, Sep 4 p.231-235
Journal articleCord blood islet autoantibodies and seasonal association with the type 1 diabetes high-risk genotype.
Kristian Lynch, Barbro Lernmark, Juan Merlo, Maria Roberta Cilio, S-A Ivarsson, et al.
(2008) Journal of Perinatology, 28 p.211-217
Journal articleChildren developing type 1 diabetes before 6 years of age have increased linear growth independent of HLA genotypes.
Helena Larsson, Gertie Hansson, Annelie Carlsson, E Cederwall, B Jonsson, et al.
(2008) Diabetologia, 51 p.1623-1630
Journal articleIncreased Lipid Oxidation Heralds Diabetes Onset in DR.lyp/lyp Rats.
Lina Åkesson, R Gelling, R Jensen, K Ogimoto, J Fuller, et al.
(2008) Experimental and Clinical Endocrinology & Diabetes, 116 p.475-480
Journal articleAnnual screening detects celiac disease in children with type 1 diabetes
Karin Larsson, Annelie Carlsson, Elisabeth Cederwall, Bjorn Jonsson, Jan Neiderud, et al.
(2008) Pediatric Diabetes, 9 p.354-359
Journal articleGAD65 vaccination significantly reduces insulin dependence at five years follow-up in a dose escalating study in adult-onset autoimmune diabetes patients
Carl-David Agardh, Kristian Lynch, M. Palmer, Katarina Link, Åke Lernmark
(2008) Diabetologia, 51 p.230-230
Conference paper: abstractAntigen presentation of detergent-free glutamate decarboxylase (GAD65) is affected by human serum albumin as carrier protein
Jordan T Steed, Lisa K Gilliam, Robert A Harris, Åke Lernmark, Christiane S Hampe
(2008) Journal of Immunological Methods, 334 p.114-121
Journal articleHLA class II alleles specify phenotypes of ketosis-prone diabetes
Ramaswami Nalini, Lakshmi K Gaur, Mario Maldonado, Christiane S Hampe, Lucille Rodriguez, et al.
(2008) Diabetes Care, 31 p.1195-1200
Journal articleComment on : Edghill et al. (2008) insulin mutation screening in 1,044 patients with diabetes: mutations in the ins gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood: diabetes 57:1034-1042, 2008
Sten A. Ivarsson, Åke Lernmark
(2008) Diabetes, 57 p.9-9
Journal article (letter)Treatment of diabetic rats with encapsulated islets
Ian R. Sweet, Ofer Yanay, Lanaya Waldron, Merle Gilbert, Jessica M. Fuller, et al.
(2008) Journal of Cellular and Molecular Medicine, 12 p.2644-2650
Journal articleImpaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5
Ryan D. Schulteis, Haiyan Chu, Xuezhi Dai, Yuhong Chen, Brandon Edwards, et al.
(2008) Blood, 112 p.4905-4914
Journal articleThe Environmental Determinants of Diabetes in the Young (TEDDY) Study
Marian Rewers, Åke Lernmark, Daniel Agardh, Peter Almgren, Carin Andrén Aronsson, et al.
(2008) Annals of the New York Academy of Sciences, 1150 p.1-13
Journal articleRelationship between increased relative birthweight and infections during pregnancy in children with a high-risk diabetes HLA genotype.
Helena Larsson, Kristian Lynch, Barbro Lernmark, Gertie Hansson, Åke Lernmark, et al.
(2007) Diabetologia, 50 p.1161-1169
Journal articleType 1 diabetes risk analysis on dried blood spot samples from population-based newborns: design and feasibility of an unselected case-control study
Stefanie Eising, Jannet Svensson, Kristin Skogstrand, Anita Ramelius, Kristian Lynch, et al.
(2007) Paediatric and Perinatal Epidemiology, 21 p.507-517
Journal articleA variant in the transcription factor 7-like 2 (TCF7L2) gene is associated with an increased risk of gestational diabetes mellitus.
Nael Shaat, Åke Lernmark, Ella Ekholm, Sten Ivarsson, Hemang Parikh, et al.
(2007) Diabetologia, 50 p.972-979
Journal articleThe environmental determinants of diabetes in the young (TEDDY) study: Study design
The TEDDY study group, Åke Lernmark, Peter Almgren, Carin Andrén Aronsson, Eva Andersson, et al.
(2007) Pediatric Diabetes, 8 p.286-298
Journal articleEpitope Analysis of GAD65 Binding in both Cord Blood and at the Time of Clinical Diagnosis of Childhood Type 1 Diabetes.
Maria Elfving, Bengt Lindberg, Kristian Lynch, Sten Ivarsson, Åke Lernmark, et al.
(2007) Hormone and Metabolic Research, 39 p.790-796
Journal articleTwo insulin gene single nucleotide polymorphisms associated with type 1 diabetes risk in the Finnish and Swedish populations
Antti-Pekka Laine, Hanna Holmberg, Anita Ramelius, E. Ortqvist, Minna Kiviniemi, et al.
(2007) Disease Markers, 23 p.139-145
Journal articleSUMO4 M55V polymorphism affects susceptibility to type I diabetes in HLA DR3- and DR4-positive Swedish patients
S K Sedimbi, X R Luo, C B Sanjeevi, Ake Lernmark, Mona Landin-Olsson, et al.
(2007) Genes and Immunity, 8 p.518-521
Journal articleMultiple factors affect the loss of measurable C-peptide over 6 years in newly diagnosed 15- to 35-year-old diabetic subjects
Richard A. Jensen, Lisa K. Gilliam, Carina Törn, Mona Landin-Olsson, F. Anders Karlsson, et al.
(2007) Journal of Diabetes and its Complications, 21 p.205-213
Journal articleNo evidence of association of the PDCD1 gene with Type 1 diabetes
S. Fawwaz, P. Nikamo, Carina Törn, Mona Landin-Olsson, Åke Lernmark, et al.
(2007) Diabetic Medicine, 24 p.1473-1477
Journal articleGAD65 autoantibody epitopes in adult patients with latent autoimmune diabetes following GAD65 vaccination
L. M. Bekris, R. A. Jensen, E. Lagerquist, T. R. Hall, Carl-David Agardh, et al.
(2007) Diabetic Medicine, 24 p.521-526
Journal articleIslet cell autoantibody levels after the diagnosis of young adult diabetic patients
R. Jensen, L. Gilliam, Carina Törn, Mona Landin-Olsson, J. Palmer, et al.
(2007) Diabetic Medicine, 24 p.1221-1228
Journal articleLow-density cells isolated from the rat thymus resemble branched cortical macrophages and have a reduced capability of rescuing double-positive thymocytes from apoptosis in the BB-DP rat.
V Sommandas, EA Rutledge, B Van Yserloo, J Fuller, Åke Lernmark, et al.
(2007) Journal of Leukocyte Biology, 4 p.869-876
Journal articleGlutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels.
LM Bekris, C Shephard, M Janer, J Graham, B McNeney, et al.
(2007) Exp Clin Endocrinol Diabetes, 115 p.221-228
Journal articleThe importance of CTLA-4 polymorphism and human leukocyte antigen genotype for the induction of diabetes-associated cytokine response in healthy school children.
CO Jonson, Åke Lernmark, J Ludvigsson, EA Rutledge, A Hinkkanen, et al.
(2007) Pediatr Diabetes, 8 p.185-192
Journal articleSpecies and epitope specificity of two 65 kDa glutamate decarboxylase time-resolved fluorometric immunoassays.
M Rui, CS Hampe, C Wang, Z Ling, FK Gorus, et al.
(2007) Journal of Immunological Methods, 319 p.133-143
Journal articleRelative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis.
G Thomson, AM Valdes, JA Noble, I Kockum, MN Grote, et al.
(2007) Tissue Antigens, 70 p.110-127
Journal articleAntibodies to GAD65 and peripheral nerve function in the DCCT.
RD Hoeldtke, CS Hampe, LM Bekris, G Hobbs, KD Bryner, et al.
(2007) Journal of Neuroimmunology, 185 p.182-189
Journal articleIA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5.
JH Shin, M Janer, B McNeney, S Blay, K Deutsch, et al.
(2007) Genes Immun., 8 p.503-512
Journal articleAtherogenic vascular and lipid phenotypes in young patients with Type 1 diabetes are associated with diabetes high-risk HLA genotype
Michal Odermarsky, Anita Ramelius, Åke Lernmark, Sture Sjöblad, Petru Liuba
(2007) American Journal of Physiology: Heart and Circulatory Physiology, 293 p.3175-3179
Journal articleDecreased core temperature and Increased beta(3)-Adrenergic sensitivity in diabetes-prone BB rats
Lina Åkesson, Tyson Hawkins, Richard Jensen, Jessica M. Fuller, Norman E. Breslow, et al.
(2007) Diabetes Technology & Therapeutics, 9 p.354-362
Journal articleThe BioBreeding rat diabetes model is infected with Ljungan virus
Bo Niklasson, T Hultman, R Kallies, M Niedrig, R. Nilsson, et al.
(2007) Diabetologia, 50 p.1559-1560
Journal article (letter)Increased galanin expression in the celiac ganglion of BB diabetic rats
Qi Mei, Thomas O Mundinger, Åke Lernmark, Gerald J Taborsky
(2006) Neuropeptides, 40 p.1-10
Journal articlePrenatal viral exposure followed by adult stress produces glucose intolerance in a mouse model.
B Niklasson, A Samsioe, M Blixt, S Sandler, A Sjöholm, et al.
(2006) Diabetologia, 49 p.2192-2199
Journal articleAge-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabetic-prone RIP-B7/DR4 mice.
John A Gebe, Kellee A Unrath, Ben A Falk, Ito Kouichi, Li Wen, et al.
(2006) Clinical Immunology, 121 p.294-304
Journal articleReduction of tissue transglutaminase autoantibody levels by gluten-free diet is associated with changes in subsets of peripheral blood lymphocytes in children with newly diagnosed coeliac disease.
Daniel Agardh, Kristian Lynch, Charlotte Brundin, S-A Ivarsson, Åke Lernmark, et al.
(2006) Clinical and Experimental Immunology, 144 p.67-75
Journal articleCommon variants in MODY genes increase the risk of gestational diabetes mellitus.
Nael Shaat, Ella Ekholm, Åke Lernmark, Sten Ivarsson, Kristian Lynch, et al.
(2006) Diabetologia, 49 p.1545-1551
Journal articleIntrogression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats.
Jessica Fuller, A E Kwitek, T J Hawkins, D H Moralejo, W Lu, et al.
(2006) Diabetes, 55 p.3351-3357
Journal articleTargeting type 1 diabetes before and at the clinical onset of disease.
L M Bekris, T J Kavanagh, Åke Lernmark
(2006) Endocrine, Metabolic & Immune Disorders - Drug Targets, 6 p.103-124
Journal articleCord blood islet autoantibodies are related to stress in the mother during pregnancy.
Barbro Lernmark, Kristian Lynch, Åke Lernmark, DiPiS Study Group
(2006) Annals of the New York Academy of Sciences, 1079 p.345-349
Journal articleTEDDY- The environmental determinants of diabetes in the young - An observational clinical trial
William A. Hagopian, Åke Lernmark, Marian J. Rewers, Olli G. Simell, Jin-Xiong She, et al.
(2006) Annals of the New York Academy of Sciences, 1079 p.320-326
Journal articleMHC class I chain-related gene-A is associated with IA2 and IAA but not GAD in Swedish type 1 diabetes mellitus
Manu Gupta, Jinko Graham, Brian McNeeny, Marian Zarghami, Mona Landin-Olsson, et al.
(2006) Annals of the New York Academy of Sciences, 1079 p.229-239
Journal articleGenetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in Sweden.
J C Roach, K Deutsch, S Li, A F Siegel, L M Bekris, et al.
(2006) American Journal of Human Genetics, 79 p.614-627
Journal articleEffects of duration of type 2 diabetes mellitus on insulin secretion.
F Zangeneh, P S Arora, P J Dyck, L Bekris, Åke Lernmark, et al.
(2006) Endocrine Practice, 12 p.388-393
Journal articleEvidence for immunological priming and increased frequency of CD4(+) CD25(+) cord blood T cells in children born to mothers with type 1 diabetes.
B C Holm, J Svensson, Christina Silver, Jeanette Arvastsson, June Ljungberg, et al.
(2006) Clinical and Experimental Immunology, 146 p.493-502
Journal articleAccuracy and predictive value of classification schemes for ketosis-prone diabetes
Ashok Balasubramanyam, Gilberto Garza, Lucille Rodriguez, Christiane S Hampe, Lakshmi K Gaur, et al.
(2006) Diabetes Care, 29 p.2575-2579
Journal articleEvidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the biobreeding rat
Rhonda Geoffrey, Shuang Jia, Anne E. Kwitek, Jeffrey Woodliff, Soumitra Ghosh, et al.
(2006) Journal of Immunology, 177 p.7275-7286
Journal articleEpitope analysis of insulin autoantibodies using recombinant Fab
C J Padoa, N J Crowther, J W Thomas, T R Hall, L M Bekris, et al.
(2005) Clinical and Experimental Immunology, 140 p.564-571
Journal articleCalcium activation of tissue transglutaminase in radioligand binding and enzyme-linked autoantibody immunoassays in childhood celiac disease.
Daniel Agardh, Bodil Roth, Åke Lernmark, Pål Stenberg
(2005) Clinica Chimica Acta, 358 p.95-103
Journal articleAutoantibodies in diabetes.
C Pihoker, L K Gilliam, C S Hampe, Åke Lernmark
(2005) Diabetes, 54 p.52-61
Journal articleDefects in differentiation of bone-marrow derived dendritic cells of the BB rat are partly associated with IDDM2 (the lyp gene) and partly associated with other genes in the BB rat background.
V Sommandas, E A Rutledge, B Van Yserloo, J Fuller, Åke Lernmark, et al.
(2005) Journal of Autoimmunity, 25 p.46-56
Journal articleGlutathione-s-transferase M1 and T1 polymorphisms and associations with type 1 diabetes age-at-onset.
L M Bekris, C Shephard, M Peterson, J Hoehna, B Van Yserloo, et al.
(2005) Autoimmunity, 38 p.567-575
Journal articleClinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes.
Carl-David Agardh, Corrado M Cilio, ÅsaLinda Lethagen, Kristian Lynch, R David G Leslie, et al.
(2005) Journal of Diabetes and its Complications, 19 p.238-246
Journal articleMedicinska biobanken - en unik resurs för medicinsk forskning
T Stigbrand, L Rymo, Åke Lernmark
(2005) Läkartidningen, 102 p.2769-2772
Journal articleIncreased risk of diabetes among relatives of female insulin-treated patients diagnosed at 15-34 years of age.
K Åkesson, L Nyström, L Färnkvist, J Ostman, Åke Lernmark, et al.
(2005) Diabetic Medicine, 22 p.1551-1557
Journal articleAutoantibodies Against Soluble and Immobilized Human Recombinant Tissue Transglutaminase in Children with Celiac Disease.
Daniel Agardh, Ingrid Dahlbom, Terri Daniels, Ester Lörinc, Sten Ivarsson, et al.
(2005) Journal of Pediatric Gastroenterology and Nutrition - Jpgn, 41 p.322-327
Journal articleDR.lyp/lyp bone marrow maintains lymphopenia and promotes diabetes in lyp/lyp but not in +/+ recipient DR.lyp BB rats
T Hawkins, J Fuller, K Olson, S Speros, Åke Lernmark
(2005) Journal of Autoimmunity, 25 p.251-257
Journal articleD6S265*15 marks a DRB1*15, DQB1*0602 haplotype associated with attenuated protection from type 1 diabetes mellitus.
A M Valdes, G Thomson, J Graham, M Zarghami, B McNeney, et al.
(2005) Diabetologia, 48 p.2540-2543
Journal article (letter)Diabetes-associated HLA genotypes affect birthweight in the general population.
Helena Larsson, Kristian Lynch, Barbro Lernmark, A Nilsson, Gertie Hansson, et al.
(2005) Diabetologia, 48 p.1484-1491
Journal articleAssociation of the E23K polymorphism in the KCNJ11 gene with gestational diabetes mellitus.
Nael Shaat, M Ekelund, Åke Lernmark, Sten Ivarsson, Peter Almgren, et al.
(2005) Diabetologia, 48 p.2544-2551
Journal articleAberrancies in the differentiation and maturation of dendritic cells from bone-marrow precursors are linked to various genes on chromosome 4 and other chromosomes of the BB-DP rat.
Vinod Sommandas, Elizabeth A. Rutledge, Brian Van Yserloo, Jessica Fuller, Åke Lernmark, et al.
(2005) Journal of Autoimmunity, 25 p.1-12
Journal articleType 1 diabetes--does suppressing T cells increase insulin?
Åke Lernmark
(2005) New England Journal of Medicine, 352 p.2642-2644
Journal article (letter)A high prevalence of organ-specific autoimmunity in patients with bipolar disorder.
Roos C Padmos, Lynn Bekris, Esther M Knijff, Henning Tiemeier, Ralph W Kupka, et al.
(2004) Biological Psychiatry, 56 p.476-482
Journal articleDevelopment of glutamic acid decarboxylase 65 (GAD65) autoantibody assay using biotin-GAD65 fusion protein.
Dong Luo, Chad N Rogers, Jordan T Steed, Lisa K Gilliam, Christiane S Hampe, et al.
(2004) Journal of Biotechnology, 111 p.97-104
Journal articleConformation-dependent GAD65 autoantibodies in diabetes
D Luo, LK Gilliam, C Greenbaum, L Bekris, CS Hampe, et al.
(2004) Diabetologia, 47 p.1581-1591
Journal articleInvolvement of eotaxin, eosinophils, and pancreatic predisposition in development of type 1 diabetes mellitus in the BioBreeding rat.
Martin J Hessner, Xujing Wang, Lisa Meyer, Rhonda Geoffrey, Shuang Jia, et al.
(2004) Journal of Immunology, 173 p.6993-7002
Journal articleTransgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat.
Mieczyslaw Michalkiewicz, Teresa Michalkiewicz, Ruth A. Ettinger, Elizabeth A. Rutledge, Jessica M. Fuller, et al.
(2004) Physiological Genomics, 19 p.228-232
Journal articleUsing radioligand-binding assays to measure tissue transglutaminase autoantibodies in young children.
Daniel Agardh, Annelie Carlsson, Kristian Lynch, Irene Axelsson, Åke Lernmark, et al.
(2004) Acta Pædiatrica, 93 p.1046-1051
Journal articleHLA-DRB1, -DQA1, and -DQB1 subtypes or ACE gene polymorphisms do not seem to be risk markers for severe retinopathy in younger Type 1 diabetic patients.
Elisabet Agardh, Lakshmi K Gaur, Åke Lernmark, Carl-David Agardh
(2004) Journal of Diabetes and its Complications, 18 p.32-36
Journal articleEpitope-restricted 65-kilodalton glutamic acid decarboxylase autoantibodies among new-onset Sardinian type 2 diabetes patients define phenotypes of autoimmune diabetes.
Mario Maioli, Emilyn Alejandro, Giancarlo Tonolo, Lisa K. Gilliam, Lynn Bekris, et al.
(2004) Journal of Clinical Endocrinology and Metabolism, 89 p.5675-5682
Journal articleSystematic screening of potential beta-cell imaging agents.
Ian R Sweet, Carla J. Cook, Åke Lernmark, Carla J. Greenbaum, Angela R Wallen, et al.
(2004) Biochemical and Biophysical Research Communications, 314 p.976-983
Journal articleImmune intervention for prevention of type 1 diabetes
Åke Lernmark
(2004) Conference Proceedings 2004 APHL NBS and Genetics Testing Symposium
Conference paperGenotypic and phenotypic differences between Arabian and Scandinavian women with gestational diabetes mellitus.
Nael Shaat, M. Ekelund, Åke Lernmark, Sten Ivarsson, A. Nilsson, et al.
(2004) Diabetologia, 47 p.878-884
Journal articleGenetic and perinatal factors as risk for childhood type 1 diabetes
K Larsson, Helena Larsson, E Cederwall, K Kockum, Sture Sjöblad, et al.
(2004) Diabetes/Metabolism Research & Reviews, 20 p.429-437
Journal article reviewNon-invasive imaging of beta cell mass: a quantitative analysis.
Ian R Sweet, Daniel L Cook, Åke Lernmark, Carla J Greenbaum, Kenneth A Krohn
(2004) Diabetes Technology & Therapeutics, 6 p.652-659
Journal articleFollow-up Report on the Diagnosis of Diabetes Mellitus
(2003) Diabetes Care, 26 p.3160-3167
Journal article reviewMolecular engineering of biotin-glutamic acid decarboxylase 65 fusion protein (Biotin-GAD65) for non-radioactive GAD65 antibody assay
Dong Luo, Chad N Rogers, Christiane S Hampe, Åke Lernmark
(2003) Journal of Biotechnology, 103 p.249-255
Journal articleGenetic dissection of lymphopenia from autoimmunity by introgression of mutated Ian5 gene onto the F344 rat.
Daniel H Moralejo, Hyunhee A Park, Sara J Speros, Armand J MacMurray, Anne E Kwitek, et al.
(2003) Journal of Autoimmunity, 21 p.315-324
Journal articleUnique epitopes of glutamic acid decarboxylase autoantibodies in slowly progressive type 1 diabetes.
Tetsuro Kobayashi, Shoichiro Tanaka, Minoru Okubo, Koji Nakanishi, Toshio Murase, et al.
(2003) Journal of Clinical Endocrinology and Metabolism, 88 p.4768-4775
Journal articleStandardization of antibody preparations for use in immunogenicity studies: a case study using the World Health Organization International Collaborative Study for Islet Cell Antibodies.
A Mire-Sluis, R Gaines Das, Åke Lernmark
(2003) Developments in Biologicals, 112 p.153-163
Journal articleImpaired glucagon response to sympathetic nerve stimulation in the BB diabetic rat: effect of early sympathetic islet neuropathy.
Thomas O Mundinger, Qi Mei, Dianne P Figlewicz, Åke Lernmark, Gerald J Jr Taborsky
(2003) American Journal of Physiology: Endocrinology and Metabolism, 285 p.1047-1054
Journal articleIslet autoantibodies in cord blood from patients who developed type 1 diabetes mellitus at 15-30 years of age.
Maria Elfving, Bengt Lindberg, Lennarth Nyström, Göran Sundkvist, Åke Lernmark, et al.
(2003) Autoimmunity, 36 p.227-231
Journal articleKetosis-prone diabetes: dissection of a heterogeneous syndrome using an immunogenetic and beta-cell functional classification, prospective analysis, and clinical outcomes
Mario Maldonado, Christiane S Hampe, Lakshmi K Gaur, Susana D'Amico, Dinakar Iyer, et al.
(2003) Journal of Clinical Endocrinology and Metabolism, 88 p.5090-5098
Journal articleMolecular Biology of β-Cell Destruction
Åke Lernmark, Choon Hee Chung
(2003) Type 1 Diabetes: Etiology and Treatment. (Contemporay Endocrinology) , p.71-71
Book chapterHigh GAD65 autoantibody levels in nondiabetic adults are associated with HLA but not with CTLA-4 or INS VNTR.
O Rolandsson, E Hägg, M Janer, E Rutledge, L K Gaur, et al.
(2003) Journal of Internal Medicine, 253 p.447-453
Journal articleDiabetes Type 1 (Insulin-Dependent Diabetes Mellitus).
Lisa K Gilliam, Åke Lernmark
(2003) Encyclopedia of Hormones, 1-3 p.398-406
Book chapterDevelopment of type 1 diabetes in wild bank voles associated with islet autoantibodies and the novel ljungan virus.
Bo Niklasson, Knud E Heller, Bryan Schønecker, Mogens Bildsøe, Terri Daniels, et al.
(2003) International journal of experimental diabesity research, 4 p.35-44
Journal articleIslet cell autoantibodies in cord blood from children with blood group incompatibility or hyperbilirubinemia.
Maria Elfving, Bengt Lindberg, Mona Landin-Olsson, Christine S Hampe, Ake Lernmark, et al.
(2003) Autoimmunity, 36 p.111-115
Journal articleType 1 diabetes in Swedish bank voles (Clethrionomys glareolus): signs of disease in both colonized and wild cyclic populations at peak density.
Bo Niklasson, Birger Hörnfeldt, Erik Nyholm, Matthias Niedrig, Oliver Donoso-Mantke, et al.
(2003) Annals of the New York Academy of Sciences, 1005 p.170-175
Journal articleBead injection ELISA for the determination of antibodies implicated in type 1 diabetes mellitus.
Andrea D Carroll, Louis Scampavia, Dong Luo, Åke Lernmark, Jaromir Ruzicka
(2003) Analyst, 128 p.1157-1162
Journal articleGAD2 on chromosome 10p12 is a candidate gene for human obesity.
Philippe Boutin, Christian Dina, Francis Vasseur, Séverine Dubois, Laetitia Corset, et al.
(2003) PLoS Biology, 1
Journal articleAssociation between the transmembrane region polymorphism of MHC class I chain related gene-A and type 1 diabetes mellitus in Sweden
Manu Gupta, Liene Nikitina-Zake, Marjan Zarghami, Mona Landin-Olsson, Ingrid Kockum, et al.
(2003) Human Immunology, 64 p.553-561
Journal articleTissue transglutaminase immunoglobulin isotypes in children with untreated and treated celiac disease
Daniel Agardh, Stefan Borulf, Åke Lernmark, Sten Ivarsson
(2003) Journal of Pediatric Gastroenterology and Nutrition - Jpgn, 36 p.77-82
Journal articleGAD65 antibody epitope patterns of type 1.5 diabetic patients are consistent with slow-onset autoimmune diabetes.
Christiane S Hampe, Ingrid Kockum, Mona Landin-Olsson, Carina Törn, Eva Ortqvist, et al.
(2002) Diabetes Care, 25 p.1481-1482
Journal article (letter)Animal models of endocrine/organ-specific autoimmune diseases: do they really help us to understand human autoimmunity?
WK Lam-Tse, Åke Lernmark, HA Drexhage
(2002) Springer Seminars in Immunopathology, 24 p.297-321
Journal articleStreptozotocin induced diabetes in minipig: a case report of a possible model for type 1 diabetes?
O Rolandsson, M F Haney, E Hagg, B Biber, Åke Lernmark
(2002) Autoimmunity, 35 p.261-264
Journal articleThe antibody response to bacteriophage is linked to the lymphopenia gene in congenic BioBreeding rats.
L Clark, C Greenbaum, J Jiang, Åke Lernmark, H Ochs
(2002) Pathogens and Disease, 32 p.205-209
Journal articleLymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.
Armand J. MacMurray, Daniel H. Moralejo, Anne E. Kwitek, Elizabeth A. Rutledge, Brian Van Yserloo, et al.
(2002) Genome Research, 12 p.1029-1039
Journal articleThe combination of several polymorphic amino acid residues in the DQ alpha and DQ beta chains forms a domain structure pattern and is associated with insulin-dependent diabetes mellitus
CB Sanjeevi, Mona Landin-Olsson, I Kockum, G Dahlquist, Åke Lernmark
(2002) Annals of the New York Academy of Sciences, 958 p.362-375
Journal articleEarly, selective, and marked loss of sympathetic nerves from the islets of BioBreeder diabetic rats.
Q Mei, TO Mundinger, Åke Lernmark, GJ Jr. Taborsky
(2002) Diabetes, 51 p.2997-3002
Journal articleMultiple sclerosis and type 1 diabetes: an unlikely alliance.
Åke Lernmark
(2002) The Lancet, 359 p.1450-1451
Journal articleStable GAD65 autoantibody epitope patterns in type 1 diabetes children five years after onset.
CS Hampe, LP Hammerle, L Bekris, E Ortqvist, B Persson, et al.
(2002) Journal of Autoimmunity, 18 p.49-53
Journal articleStudies on the association between 2'5'-oligoadenylate synthetase and type 1 diabetes.
M Zarghami, V Bonnevie-Nielsen, R Tobias, M Engel, J Graham, et al.
(2002) [Host publication title missing]
Conference paperProtein-free diets do not protect high-incidence diabetes-prone BioBreeding rats from diabetes.
W Simonson, S Ramanathan, S Bieg, P Poussier, Åke Lernmark
(2002) Metabolism: Clinical and Experimental, 51 p.569-574
Journal articleInduction of donor-specific tolerance to islet allografts in nonhuman primates.
LK Gaur, E Kennedy, Y Nitta, GT Nepom, KA Nelson, et al.
(2002) Annals of the New York Academy of Sciences, 958 p.194-198
Journal articleSerum IgG to heat shock proteins and Porphyromonas gingivalis antigens in diabetic patients with periodontitis.
TJ Sims, Åke Lernmark, LA Mancl, RE Schifferle, RC Page, et al.
(2002) Journal of Clinical Periodontology, 29 p.551-562
Journal articleType 1 diabetes as a model for prediction and diagnosis.
Åke Lernmark
(2002) Autoimmunity, 37 p.341-345
Journal articleMacrophages from high-risk HLA-DQB1*0201/*0302 type 1 diabetes mellitus patients are hypersensitive to lipopolysaccharide stimulation.
A Plesner, C J Greenbaum, L K Gaur, R K Ernst, Åke Lernmark
(2002) Scandinavian Journal of Immunology, 56 p.522-529
Journal articleTissue transglutaminase autoantibodies and human leucocyte antigen in Down's syndrome patients with coeliac disease.
Daniel Agardh, A Nilsson, Annelie Carlsson, I Kockum, A Lernmark, et al.
(2002) Acta Pædiatrica, 91 p.34-38
Journal articleGenetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes.
J Graham, WA Hagopian, I Kockum, LS Li, CB Sanjeevi, et al.
(2002) Diabetes, 51 p.1346-1355
Journal articleControlling the controls: GAD65 autoreactive T cells in type 1 diabetes.
Åke Lernmark
(2002) Journal of Clinical Investigation, 109 p.869-870
Journal article (letter)Type 1 diabetes-related autoantibodies are rare in Alaska native populations.
J Mohatt, LK Gilliam, L Bekris, S Ebbesson, Åke Lernmark
(2002) International Journal of Circumpolar Health, 61 p.21-31
Journal articleGAD65 and IA-2 autoantibodies are common in a subset of siblings of Sardinian Type 2 diabetes families.
Mario Maioli, G Tonolo, L Bekris, R Cirillo, D Schranz, et al.
(2002) Diabetes Research and Clinical Practice, 56 p.41-47
Journal articleDynamic perifusion to maintain and assess isolated pancreatic islets.
I R Sweet, D L Cook, R W Wiseman, C J Greenbaum, Åke Lernmark, et al.
(2002) Diabetes Technology & Therapeutics, 4 p.67-76
Journal articleInduction of islet allotolerance in nonhuman primates
Lakshmi K Gaur, Y Nitta, E. Kennedy, Å Lernmark, Keith A. Nelson, et al.
(2002) Annals of the New York Academy of Sciences, 958 p.199-203
Journal articleGene and Cell-Replacement Therapy in the Treatment of Type 1 Diabetes : How High Must the Standards Be Set?
Philippe A Halban, Steven E Kahn, Åke Lernmark, Christopher J. Rhodes
(2001) Diabetes, 50 p.2181-2191
Journal article reviewTreatment outcome for IDDM patients in relation to glutamic acid decarboxylase autoantibodies and serum IgG to periodontal pathogens
Tom J. Sims, Åke Lernmark, Todd Smith, Roy C. Page, G. Rutger Persson
(2001) Journal of Clinical Periodontology, 28 p.550-557
Journal articleLow serum conditions for in vitro generation of human macrophages with macrophage colony stimulating factor
Annette Plesner, Carla J Greenbaum, Åke Lernmark
(2001) Journal of Immunological Methods, 249 p.53-61
Journal articleA novel monoclonal antibody specific for the N-terminal end of GAD65
Christiane S Hampe, Per Lundgren, Terri L Daniels, Lisa P Hammerle, Santica M. Marcovina, et al.
(2001) Journal of Neuroimmunology, 113 p.63-71
Journal articleGlucose-regulated insulin expression in diabetic rats
S. C. Barry, N. Ramesh, D. V. Lejnieks, William T Simonson, L. Kemper, et al.
(2001) Human Gene Therapy, 12 p.131-139
Journal articleSite-directed mutagenesis of K396R of the 65 kDa glutamic acid decarboxylase active site obliterates enzyme activity but not antibody binding
Christiane S Hampe, Lisa P Hammerle, Alberto Falorni, John D. Robertson, Åke Lernmark
(2001) FEBS Letters, 488 p.185-189
Journal articlePrediction of silent celiac disease at diagnosis of childhood type 1 diabetes by tissue transglutaminase autoantibodies and HLA
Daniel Agardh, Anita Ramelius, Tiinamaija Toumi, Bengt Lindberg, Anneli K Carlsson, et al.
(2001) Pediatric Diabetes, 2 p.58-65
Journal articleCombinations of beta cell specific autoantibodies at diagnosis of diabetes in young adults reflects different courses of beta cell damage
Carina Törn, Mona Landin-Olsson, Åke Lernmark, Bengt Scherstén, J. Ostman, et al.
(2001) Autoimmunity, 33 p.115-120
Journal articleActivated human epitope-specific T cells identified by class II tetramers reside within a CD4high, proliferating subset
Erik J. Novak, Susan A. Masewicz, Andrew W. Liu, Åke Lernmark, William W. Kwok, et al.
(2001) International Immunology, 13 p.799-806
Journal articlePreservation of enzyme activity and antigenicity after mutagenesis of the membrane anchoring domain of GAD65
Annette Plesner, Christiane S Hampe, Terri L Daniels, Lisa P Hammerle, Åke Lernmark
(2001) Autoimmunity, 34 p.221-230
Journal articleLow-dose streptozotocin induces sustained hyperglycemia in Macaca nemestrina
L K Gaur, Gerald T Nepom, Å Lernmark
(2001) Autoimmunity, 33 p.103-114
Journal articleAutoimmune diseases : Are markers ready for prediction?
Åke Lernmark
(2001) Journal of Clinical Investigation, 108 p.1091-1096
Journal article reviewMolecular manipulation of autoantibody testing in type 1 diabetes : Two for one
David B. Sacks, A. Lernmark
(2001) Clinical Chemistry, 47 p.803-804
Journal article (comment)Autoimmune type 1 diabetes : Resolved and unresolved issues
Abner Louis Notkins, Åke Lernmark
(2001) Journal of Clinical Investigation, 108 p.1247-1252
Journal article reviewPrediction of diabetes with body mass index, oral glucose tolerance test and islet cell autoantibodies in a regional population
O Rolandsson, E. Hägg, M. Nilsson, G Hallmans, Lucia Mincheva-Nilsson, et al.
(2001) Journal of Internal Medicine, 249 p.279-288
Journal articleType 1 (Insulin-Dependent) Diabetes Mellitus: : Etiology, Pathogenesis, and Natural History
Ake Lernmark
(2001) Endocrinology , p.763-775
Book chapterComparison of the prevalence of glutamic acid decarboxylase (GAD65) and gliadin antibodies (AGA) in a randomly selected adult estonian population
R Uibo, E P Sullivan, O Uibo, A Lernmark, L Salur, et al.
(2001) Hormone and Metabolic Research, 33 p.7-564
Journal articleEvaluation of a novel radioimmunoassay using 125I-labelled human recombinant GAD65 for the determination of glutamic acid decarboxylase (GAD65) autoantibodies
Santica M. Marcovina, M. Landin-Olsson, A. Essen-Möller, J. P. Palmer, Å Lernmark
(2000) International Journal of Clinical and Laboratory Research, 30 p.21-26
Journal articleAlternative splicing of GAD67 results in the synthesis of a third form of glutamic-acid decarboxylase in human islets and other non-neural tissues
Steven D. Chessler, Åke Lernmark
(2000) Journal of Biological Chemistry, 275 p.5188-5192
Journal articleRapid-onset type 1 diabetes with pancreatic exocrine dysfunction
A. Lernmark
(2000) New England Journal of Medicine, 342 p.344-345
Journal article (comment)Rel B is an early marker of autoimmune islet inflammation in the BioBreeding (BB) rat
Sabine Bieg, William T Simonson, Kristian Ellefsen, Åke Lernmark
(2000) Pancreas, 20 p.47-54
Journal articleKetoacidosis in young adults is not related to the islet antibodies at the diagnosis of Type 1 diabetes mellitus - A nationwide study
Jan Östman, M. Landin-Olsson, C. Törn, J. Palmer, A. Lernmark, et al.
(2000) Diabetic Medicine, 17 p.269-274
Journal articleAntibodies to glutamic acid decarboxylase and peripheral nerve function in type 1 diabetes
Robert D. Hoeldtke, Kimberly D. Bryner, Gerald R. Hobbs, Gabriella G. Horvath, Jack E. Riggs, et al.
(2000) Journal of Clinical Endocrinology and Metabolism, 85 p.3297-3308
Journal articleThe length of the CTLA-4 microsatellite (AT)(N)-repeat affects the risk for type 1 diabetes
Michael R. Lowe, J Graham, G. Sund, I Kockum, M. Landin-Olsson, et al.
(2000) Autoimmunity, 32 p.173-180
Journal articleGAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65
Charlotta af Hällström-Reijonen, Terri L Daniels, A. Lernmark, Gerald T Nepom
(2000) Diabetes, 49 p.1621-1626
Journal articlePrognostic factors for the course of β cell function in autoimmune diabetes
C. Törn, M. Landin-Olsson, Å Lernmark, J. P. Palmer, H. J. Arnqvist, et al.
(2000) Journal of Clinical Endocrinology and Metabolism, 85 p.4619-4623
Journal articleStability of disease-associated antibody titers in pregnant women with type 1 diabetes with or without residual β-cell function [2]
Eva Nord, Lena Edwall, Christiane S Hampe, Lynn Bekris, Bengt E. Persson, et al.
(2000) Diabetes Care, 23 p.1019-1021
Journal article (letter)Newly diagnosed latent autoimmune diabetes in adults (LADA) is associated with low level glutamate decarboxylase (GAD65) and IA-2 autoantibodies
D. B. Schranz, L Bekris, M. Landin-Olsson, C. Törn, A. Niläng, et al.
(2000) Hormone and Metabolic Research, 32 p.133-138
Journal articleRecognition of glutamic acid decarboxylase (GAD) by autoantibodies from different GAD antibody-positive phenotypes
Christiane S Hampe, Lisa P Hammerle, Lynn Bekris, Eva Örtqvist, Ingrid Kockum, et al.
(2000) Journal of Clinical Endocrinology and Metabolism, 85 p.4671-4679
Journal articleGlutamic acid decarboxylase antibodies (GADA) is the most important factor for prediction of insulin therapy within 3 years in young adult diabetic patients not classified as Type 1 diabetes on clinical grounds
Carina Törn, Mona Landin-Olsson, Jan Östman, Bengt Scherstén, Hans Arnqvist, et al.
(2000) Diabetes/Metabolism Research and Reviews, 16 p.442-447
Journal articleThe World Health Organization international collaborative study for islet cell antibodies
A. R. Mire-Sluis, R Gaines Das, Å. Lernmark
(2000) Diabetologia, 43 p.1282-1292
Journal articleThe role of glutamic acid decarboxylase and GABA in the pancreas and diabetes.
Steven D. Chessler, Åke Lernmark
(2000) GABA in the Nervous System: : The View at Fifty Years , p.471-484
Book chapterEpitope-specific glutamic acid decarboxylase-65 autoantibodies in intravenous immunoglobulin preparations
W. Hao, C. Davis, T. Daniels, C. S. Hampe, Å Lernmark
(1999) Transfusion Medicine, 9 p.307-310
Journal articleIslet autoantibodies in cord blood could be a risk factor for future diabetes [5]
B. Lindberg, S. A. Ivarsson, A. Lernmark
(1999) Diabetologia, 42 p.1443-1443
Journal article (letter)HLA associations in type 1 diabetes among patients not carrying high-risk DR3-DQ2 or DR4-DQ8 haplotypes
Dag E. Undlien, I. Kockum, K. S. Rønningen, R. Lowe, C. B. Saanjeevi, et al.
(1999) Tissue Antigens, 54 p.543-551
Journal articleVaccination mot typ 1-diabetes framme vid kliniska försöksstadiet
Åke Lernmark
(1999) Läkartidningen, 96 p.1300-1302
Journal articleTolerance to kidney allograft transplanted into Type I diabetic patients persists after in vivo challenge with pancreatic islet allografts that express repeated mismatches [5]
I. Stobbe, G. Duinkerken, J. J. Van Rood, A. Lernmark, B. Keymeulen, et al.
(1999) Diabetologia, 42 p.1379-1380
Journal article (letter)Islet autoantibodies in cord blood could be a risk factor for future diabetes [1]
B. Lindberg, S. A. Ivarsson, A. Lernmark
(1999) Diabetologia, 42 p.1375-1375
Journal article (letter)Complex interaction between HLA DR and DQ in conferring risk for childhood type 1 diabetes
I. Kockum, C. B. Sanjeevi, S. Eastman, M. Landin-Olsson, G. Dahlquist, et al.
(1999) European Journal of Immunogenetics, 26 p.361-372
Journal articleBB rat diabetes susceptibility and body weight regulation genes colocalize on Chromosome 2
Lindy S. Klaff, George Koike, Jianjie Jiang, Yanling Wang, Sabine Bieg, et al.
(1999) Mammalian Genome, 10 p.883-887
Journal articlePlasmapheresis and immunosuppression in stiff-man syndrome with type 1 diabetes : A 2-year study [5]
W. Hao, C. Davis, I. B. Hirsch, L. J. Eng, T. Daniels, et al.
(1999) Journal of Neurology, 246 p.731-735
Journal article (letter)A diabetogenic gene prevents T cells from receiving costimulatory signals
Jodene K. Moore, Daniel P. Gold, Stephen C. Dreskin, Åke Lernmark, Donald Bellgrau
(1999) Cellular Immunology, 194 p.90-97
Journal articleNegative association between type 1 diabetes and HLA DQB1*0602-DQA1*0102 is attenuated with age at onset
Jinko Graham, Ingrid Kockum, Carani B. Sanjeevi, Mona Landin-Olsson, Lennarth Nyström, et al.
(1999) European Journal of Immunogenetics, 26 p.117-127
Journal articleGlutamate decarboxylase (GAD65) and tyrosine phosphatase-like protein (IA-2) autoantibodies index in a regional population is related to glucose intolerance and body mass index
O. Rolandsson, E. Hägg, C. Hampe, E. P. Sullivan, M. Nilsson, et al.
(1999) Diabetologia, 42 p.555-559
Journal articleSpecies-specific autoantibodies in type 1 diabetes
C. S. Hampe, E. Örtqvist, O. Rolandsson, M. Landin-Olsson, C. Törn, et al.
(1999) Journal of Clinical Endocrinology and Metabolism, 84 p.643-648
Journal articleA conformation-dependent epitope in Addison's disease and other endocrinological autoimmune diseases maps to a carboxyl-terminal functional domain of human steroid 21-hydroxylase
Andrej Nikoshkov, Alberto Falorni, Svetlana Lajic, Stefano Laureti, Anna Wedell, et al.
(1999) Journal of Immunology, 162 p.2422-2426
Journal articleIslet autoantibodies in cord blood from children who developed type I (insulin-dependent) diabetes mellitus before 15 years of age
B. Lindberg, S. A. Ivarsson, M. Landin-Olsson, G. Sundkvist, L. Svanberg, et al.
(1999) Diabetologia, 42 p.181-187
Journal articleTowards a World Health Organisation (WHO) approved standard sample for islet cell antibodies, GAD65 and IA-2 autoantibodies [2]
A. Lernmark, H. Kolb, T. Mire-Sluis
(1999) Diabetologia, 42 p.381-382
Journal article (letter)Prevalence of β-cell and Thyroid Autoantibody Positivity in Schoolchildren during Three-Year Follow-up
Bengt Lindberg, Annelie Carlsson, Ulla-Britt Ericsson, Ingrid Kockum, Åke Lernmark, et al.
(1999) Autoimmunity, 31 p.175-185
Journal articleSelecting culprits in type 1 diabetes β-cell killing
A. Lernmark
(1999) Journal of Clinical Investigation, 104 p.1487-1489
Journal article (comment)Previous exposure to measles, mumps, and rubella--but not vaccination during adolescence--correlates to the prevalence of pancreatic and thyroid autoantibodies.
B. Lindberg, K. Ahlfors, A. Carlsson, U. B. Ericsson, M. Landin-Olsson, et al.
(1999) Pediatrics, 104 p.1-5
Journal articleRadioimmunoassay for glutamic acid decarboxylase-65.
W. Hao, T. Daniels, D. G. Pipeleers, A. Smismans, H. Reijonen, et al.
(1999) Diabetes Technology & Therapeutics, 1 p.13-20
Journal articleAppearance of islet cell autoantibodies after clinical diagnosis of diabetes mellitus
Mona Landin-Olsson, Hans J. Arnqvist, Göran Blohmé, Bengt Littorin, Folke Lithner, et al.
(1999) Autoimmunity, 29 p.57-63
Journal articleThe development of a World Health Organisation international standard for islet cell antibodies : The aims and design of an international collaborative study
Anthony R. Mire-Sluis, Rose Gaines Das, Åke Lernmark
(1999) Diabetes/Metabolism Research and Reviews, 15 p.72-77
Journal articleIslet cell and glutamic acid decarboxylase antibodies present at diagnosis of diabetes predict the need for insulin treatment : A cohort study in young adults whose disease was initially labeled as type 2 or unclassifiable diabetes
Bengt Littorin, Goran Sundkvist, William Hagopian, Mona Landin-Olsson, Åke Lernmark, et al.
(1999) Diabetes Care, 22 p.409-412
Journal articleAuto- and alloimmune reactivity to human islet allografts transplanted into type 1 diabetic patients
Bart O. Roep, Inge Stobbe, Gaby Duinkerken, Jon J. Van Rood, Åke Lernmark, et al.
(1999) Diabetes, 48 p.484-490
Journal articleRecombinant human platelet-activating factor acetylhydrolase reduces the frequency of diabetes in the diabetes-prone BB rat
Edmond S. Lee, Jianjie Jiang, Greg C. Sund, William T. Simonson, Jinko Graham, et al.
(1999) Diabetes, 48 p.43-49
Journal articleInfluence of heredity on the appearance of islet autoantibodies in cordblood from children developing type I diabetes before 15 years of age [2]
B. Lindberg, S. A. Ivarsson, Å Lernmark
(1999) Diabetologia, 42 p.896-897
Journal article (letter)Glutamate decarboxylase (GAD) autoantibody epitope shift during the first year of Type 1 diabetes
C. S. Hampe, E. Örtqvist, B. Persson, D. B. Schranz, Å Lernmark
(1999) Hormone and Metabolic Research, 31 p.553-557
Journal articleDiabetes resistance in the BB rat maps to a body weight regulator on chromosome 2
L. S. Klaff, G. Koike, J. Jiang, Y. Wang, S. Bieg, et al.
(1999) Journal of Investigative Medicine, 47 p.2-2
Conference paper: abstractThird Seattle Islet Symposium : Recent advances in signaling mechanisms common to the nervous system and islets
D. G. Baskin, A. Lernmark
(1999) Hormone and Metabolic Research, 31 p.329-329
Conference prefaceAnimal Models for Insulin-Dependent Diabetes Mellitus
Sabine Bieg, Åke Lernmark
(1999) Contemporary endocrinology, 15 p.113-139
Book chapterEtiological diagnosis of primary adrenal insufficiency using an original flowchart of immune and biochemical markers
Stefano Laureti, Patrick Aubourg, Filippo Calcinaro, Francis Rocchiccioli, Giovanni Casucci, et al.
(1998) Journal of Clinical Endocrinology and Metabolism, 83 p.3163-3168
Journal articleSevere insulin resistance in a patient with type 1 diabetes and stiff- man syndrome treated with insulin lispro
Irl B. Hirsch, David D'Alessio, Lily Eng, Connie Davis, Åke Lernmark, et al.
(1998) Diabetes Research and Clinical Practice, 41 p.197-202
Journal article (comment)Sometimes it's hot, sometimes it's not
Åke Lernmark, Jurg Ott
(1998) Nature Genetics, 19 p.213-214
Journal article (comment)Pituitary autoantibodies in patients with hypopituitarism and their relatives
S. Strömberg, P. Crock, Å Lernmark, A. L. Hulting
(1998) Journal of Endocrinology, 157 p.475-480
Journal articleGenetic isolation of iddm 1 on Chromosome 4 in the BioBreeding (BB) rat
Sabine Bieg, G. Koike, J. Jiang, L. Klaff, A. Pettersson, et al.
(1998) Mammalian Genome, 9 p.324-326
Journal articleA simple and rapid microSepharose assay for GAD65 and ICA512 autoantibodies in diabetes
Dorota B. Schranz, Lynn Bekris, Mona Landin-Olsson, Carina Törn, Anna Niläng, et al.
(1998) Journal of Immunological Methods, 213 p.87-97
Journal articleAssociation between autoantibody markers and subtypes of DR4 and DR4-DQ in Swedish children with insulin-dependent diabetes reveals closer association of tyrosine pyrophosphatase autoimmunity with DR4 than DQ8
C. B. Sanjeevi, W. A. Hagopian, M. Landin-Olsson, I. Kockum, W. Woo, et al.
(1998) Tissue Antigens, 51 p.281-286
Journal articleImmunology in diabetes : An update
Dorota B. Schranz, Åke Lernmark
(1998) Diabetes/Metabolism Reviews, 14 p.3-29
Journal article reviewInverse relationship between GAD65 antibody levels and severe retinopathy in younger type 1 diabetic patients
Daniel Agardh, Elisabet Agardh, Mona Landin-Olsson, Lakshmi K Gaur, Carl-David Agardh, et al.
(1998) Diabetes Research and Clinical Practice, 40 p.9-14
Journal articleType 1 (Insulin-Dependent) Diabetes Mellitus
Steven D. Chessler, Åke Lernmark
(1998) Clinical diabetes mellitus: : a problem-oriented approach, 3 p.37-57
Book chapterBeta Cell Antigens
A Plesner, Åke Lernmark
(1998) Immunology and Medicine Series, 27 p.113-144
Book chapterCombined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: : Combinatorial Islet Autoantibody Workshop
C F Verge, D Stenger, E Bonifacio, P G Colman, C Pilcher, et al.
(1998) Diabetes, 47 p.1857-1866
Journal articleDiabetes : (Part II. Organs and Tissues)
Sabine Bieg, Åke Lernmark
(1998) The autoimmune diseases , p.431-457
Book chapterImmune surveillance : Paraneoplastic or environmental triggers of autoimmunity
Åke Lernmark
(1997) Critical Reviews in Immunology, 17 p.437-447
Conference paperGlutamate decarboxylase antibodies in non-diabetic pregnancy precedes insulin-dependent diabetes in the mother but not necessarily in the offspring
Sten-A. Ivarsson, Malin Ackefors, Göran Ekberg, Alberto Falorni, Ingrid Kockum, et al.
(1997) Autoimmunity, 26 p.261-269
Journal articleThe beta cell glucokinase promoter variant is an unlikely risk factor for diabetes mellitus
K. Lotfi, G. Sund, R. Lowe, J. Graham, M. Landin-Olsson, et al.
(1997) Diabetologia, 40 p.959-962
Journal articleThe lymphopenia (lyp) gene controls the intrathymic cytokine ratio in congenic biobreeding rats
S. Bieg, C. Möller, T. Olsson, Å Lernmark
(1997) Diabetologia, 40 p.786-792
Journal articleRegulation of islet growth : Reports from the second Seattle islet symposium
A. Lernmark
(1997) Hormone and Metabolic Research, 29 p.264-264
Journal articleFamily cell lines available for research - An endangered resource? [7]
A. Lernmark, George Eisenbarth, lee Ducat, Henry Erlich, Denise Faustman, et al.
(1997) American Journal of Human Genetics, 61 p.778-779
Journal article (letter)Antibodies to GAD and glycemic control in recent-onset IDDM
Robert D. Hoeldtke, Kimberly D. Bryner, Gabriella G. Horvath, Michele R. Byerly, Gerald R. Hobbs, et al.
(1997) Diabetes Care, 20 p.1900-1903
Journal articleAssociations of GAD65- and IA-2-autoantibodies with genetic risk markers in new-onset IDDM patients and their siblings : The Belgian Diabetes Registry
Christina L. Vandewalle, Alberto Falorni, Åke Lernmark, Patrick Goubert, Harry Dorchy, et al.
(1997) Diabetes Care, 20 p.1547-1552
Journal articleTranscript of open discussion
G. Nepom, B. Singh, D. Gold, L. Sherman, A. Lernmark, et al.
(1997) Critical Reviews in Immunology, 18 p.145-152
Journal article (comment)Age governs gender-dependent islet cell autoreactivity and predicts the clinical course in childhood IDDM
E. Örtqvist, A. Falorni, A. Scheynius, B. Persson, Å Lernmark
(1997) Acta Paediatrica, International Journal of Paediatrics, 86 p.1166-1171
Journal articleAutoantibodies to the GM2-1 islet ganglioside and to GAD-65 at type 1 diabetes onset
Francesco Dotta, Alberto Falorni, Claudio Tiberti, Sabrina Dionisi, Emanuela Anastasi, et al.
(1997) Journal of Autoimmunity, 10 p.585-588
Journal articleAnalysis of critical residues of HLA-DQ6 molecules in insulin-dependent diabetes mellitus
C. B. Sanjeevi, C. DeWeese, M. Landin-Olsson, I. Kockum, G. Dahlquist, et al.
(1997) Tissue Antigens, 50 p.61-65
Journal articlePathophysiology of type I (insulin-dependent) diabetes
JP Palmer, Åke Lernmark
(1997) Ellenberg and Rifkin's Diabetes Mellitus: : Theory and Practice , p.455-476
Book chapterDifferent HLA-DR-DQ haplotypes are associated with cervical intraepithelial neoplasia among human papillomavirus type-16 seropositive and seronegative Swedish women
C. B. Sanjeei, P. Hjelmström, G. Hallmans, F. Wiklund, P. Lenner, et al.
(1996) International Journal of Cancer, 68 p.409-414
Journal articleNaturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes- associated human MHC class II allele, DRB1*0401
Linda S. Wicker, Shiow Ling Chen, Gerald T. Nepom, John F. Elliott, Daniel C. Freed, et al.
(1996) Journal of Clinical Investigation, 98 p.2597-2603
Journal articleAntibodies to glutamic acid decarboxylase and insulin-dependent diabetes in patients with autoimmune polyendocrine syndrome type I
Tiinamaija Tuomi, Petra Björses, Alberto Falorni, Jukka Partanen, Jaakko Perheentupa, et al.
(1996) Journal of Clinical Endocrinology and Metabolism, 81 p.1488-1494
Journal articleHLA and glutamic acid decarboxylase in human insulin-dependent diabetes mellitus
C. B. Sanjeevi, A. Falorni, I. Kockum, W. A. Hagopian, Å Lernmark
(1996) Diabetic Medicine, 13 p.209-217
Journal articleHLA class II is associated with the frequency of glutamic acid decarboxylase M(r) 65,000 autoantibodies in Japanese patients with insulin dependent diabetes mellitus
A. Kasuga, A. Falorni, T. Maruyama, Y. Ozawa, C. E. Grubin, et al.
(1996) Acta Diabetologica, 33 p.108-113
Journal articleAutoimmune (type 1) diabetes in young adults in Sweden
J. Östman, Å Lernmark, Mona Landin-Olsson, G. Sundkvist, J. Palmer, et al.
(1996) Hormone and Metabolic Research, 28 p.348-350
Journal articleGenetic and immunological findings in patients with newly diagnosed insulin-dependent diabetes mellitus
Ingrid Kockum, Å Lernmark, Gisela Dahlquist, A. Falorni, W. A. Hagopian, et al.
(1996) Hormone and Metabolic Research, 28 p.344-347
Journal articleAssociation between HLA and islet cell antibodies in diabetic patients with a mitochondrial DNA mutation at base pair 3243
T. Kobayashi, Y. Oka, H. Katagiri, A. Falornl, A. Kasiiga, et al.
(1996) Diabetologia, 39 p.1196-1200
Journal articleIslet cell and glutamic acid decarboxylase antibodies in hyperthyroid patients : At diagnosis and following treatment
B. Hallengren, A. Falorni, M. Landin-Olsson, Å Lernmark, K. I. Papadopoulos, et al.
(1996) Journal of Internal Medicine, 239 p.63-68
Journal articleDR4 subtypes and their molecular properties in a population-based study of Swedish childhood diabetes
C. B. Sanjeevi, P. Höök, M. Landin-Olsson, I. Kockum, G. Dahlquist, et al.
(1996) Tissue Antigens, 47 p.275-283
Journal articleA comparison of three statistical models for IDDM associations with HLA
J. Graham, I. Kockum, N. Breslow, Å Lernmark, E. Holmberg
(1996) Tissue Antigens, 48 p.1-14
Journal articleGlutamic acid decarboxylase (GAD) in insulin-dependent diabetes mellitus
C. B. Sanjeevi, A. Falorni, J. Robertson, Å Lernmark
(1996) Diabetes, Nutrition and Metabolism - Clinical and Experimental, 9 p.167-182
Journal articleDiagnostic sensitivity of immunodominant epitopes of glutamic acid decarboxylase (GAD65) autoantihodies in childhood IDDM
A. Falorni, M. Ackefors, C. Carlberg, T. Daniels, B. Persson, et al.
(1996) Diabetologia, 39 p.1091-1098
Journal articleGlutamic acid decarboxylase - Gene to antigen to disease
Å Lernmark
(1996) Journal of Internal Medicine, 240 p.259-277
Journal article reviewAntibody to the Mr 65,000 isoform of glutamic acid decarboxylase are detected in non-insulin-dependent diabetes in Japanese
A. Kasuga, T. Maruyama, Y. Ozawa, I. Takei, A. Falorni, et al.
(1996) Journal of Autoimmunity, 9 p.105-111
Journal articleHLA-DQB1*0201/0302 is associated with severe retinopathy in patients with IDDM
Daniel Agardh, L K Gaur, Elisabet Agardh, Mona Landin-Olsson, Carl-David Agardh, et al.
(1996) Diabetologia, 39 p.1313-1317
Journal articlePrediction - Lessons from animal models: : The BB rat
A. Pettersson, H Jacob, Ake Lernmark
(1996) Prediction, Prevention and Genetic Counseling in DDM , p.181-200
Book chapterHumoral Autoimmunity
Åke Lernmark
(1996) Diabetes Mellitus : : A fundamental and Clinical Text , p.298-307
Book chapterIslet Cell Autoantibodies
William A. Hagopian, Ake Lernmark
(1996) Autoantibodies , p.441-448
Book chapterSexual dimorphism in transmission of expression of islet autoantibodies to offspring
L. Yu, H. P. Chase, A. Falorni, M. Rewers, Å Lernmark, et al.
(1995) Diabetologia, 38 p.1353-1357
Journal articleRadioimmunoassays for glutamic acid decarboxylase (GAD65) and GAD65 autoantibodies using 35S or 3H recombinant human ligands
Alberto Falorni, Eva Örtqvist, Bengt Persson, Åke Lernmark
(1995) Journal of Immunological Methods, 186 p.89-99
Journal articlePredictability of heterozygosity scores and polymorphism information content values for rat genetic markers
A. Pettersson, E. S. Winer, S. Weksler-Zangen, Å Lernmark, H. J. Jacob
(1995) Mammalian Genome, 6 p.512-520
Journal articleHigh diagnostic accuracy for idiopathic Addison’s disease with a sensitive radiobinding assay for autoantibodies against recombinant human 21-hydroxylase
Alberto Falorni, Andrej Nikoshkov, Stefano Laureti, Eva Grenb�ck, Anna Lena Hulting, et al.
(1995) Journal of Clinical Endocrinology and Metabolism, 80 p.2752-2755
Journal articleT cells from BB-DP rats show a unique cytokine mRNA profile associated with the IDDMI susceptibility gene, LYP
Daniel P. Gold, Samuel T. Shaikewitz, Deanna Mueller, Joan R. Redd, Karen S. Sellins, et al.
(1995) Autoimmunity, 22 p.149-161
Journal articleInterferon expression in the pancreases of patients with type I diabetes
Xiaojian Huang, Jean Yuan, Audrey Goddard, Alan Foulis, Roger F.L. James, et al.
(1995) Diabetes, 44 p.658-664
Journal articleThyroiditis in the BB rat is associated with lymphopenia but occurs independently of diabetes
Anna Pettersson, Deborah Wilson, Terri Daniels, Sarina Tobin, Howard J. Jacob, et al.
(1995) Journal of Autoimmunity, 8 p.493-505
Journal articleGlutamate decarboxylase antibody levels predict rate of β-cell decline in adult-onset diabetes
A. Gottsäter, M. Landin-Olsson, Å Lernmark, P. Fernlund, G. Sundkvist, et al.
(1995) Diabetes Research and Clinical Practice, 27 p.133-140
Journal articleEffects of the second HLA‐DQ haplotype on the association with childhood insulin‐dependent diabetes mellitus
C. B. Sanjeevi, M. Landin‐Olsson, I. Kockum, G. Dahlquist, Å Lernmark
(1995) Tissue Antigens, 45 p.148-152
Journal articleHeterogeneity of islet pathology in two infants with recent onset diabetes mellitus
Å Lernmark, D. Stenger, D. G. Baskin, J. P. Palmer, L. Li, et al.
(1995) Virchows Archiv, 425 p.631-640
Journal articleTargeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2- terminal region of the 65-kDa isoform of glutamic acid decarboxylase
R. Dirkx, A. Thomas, L. Li, A. Lernmark, R. S. Sherwin, et al.
(1995) Journal of Biological Chemistry, 270 p.2241-2246
Journal articleGlutamate decarboxylase-, insulin-, and islet cell-antibodies and HLA typing to detect diabetes in a general population-based study of Swedish children
William A. Hagopian, Carani B. Sanjeevi, Ingrid Kockum, Mona Landin-Olsson, Allan E. Karlsen, et al.
(1995) Journal of Clinical Investigation, 95 p.1505-1511
Journal articleFlow injection fluorescence microscopy applied to a rapid cell surface immunoassay
Cy H. Pollema, Åke Lernmark, Jaromir Ruzicka
(1995) Cytometry, 19 p.70-76
Journal articleHigh diagnostic sensitivity of glutamate decarboxylase autoantibodies in insulin-dependent diabetes mellitus with clinical onset between age 20 and 40 years
Christina L. Vandewalle, Alberto Falorni, Sigrun Svanholm, Åke Lernmark, Daniel G. Pipeleers, et al.
(1995) Journal of Clinical Endocrinology and Metabolism, 80 p.846-851
Journal articleGlutamic acid decarboxylase antibodies and diabetes complications : Assay reliability and validity
A. Lernmark
(1995) Diabetes Care, 18 p.269-271
Journal article (comment)A genetic linkage map of the laboratory rat, Rattus norvegicus
Howard J. Jacob, Donna M. Brown, Ruth K. Bunker, Mark J. Daly, Victor J. Dzau, et al.
(1995) Nature Genetics, 9 p.63-69
Journal articlePolymorphic amino acid variations in HLA-DQ are associated with systematic physical property changes and occurrence of IDDM
C. B. Sanjeevi, T. P. Lybrand, C. Deweese, M. Landin-Olsson, I. Kockum, et al.
(1995) Diabetes, 44 p.125-131
Journal articlePOPULATION ANALYSIS OF PROTECTION BY HLA‐DR AND DQ GENES FROM INSULIN‐DEPENDENT DIABETES MELLITUS IN SWEDISH CHILDREN WITH INSULIN‐DEPENDENT DIABETES AND CONTROLS
I. Kockum, C. B. Sanjeevi, S. Eastman, M. Landin‐Olsson, G. Dahlouist, et al.
(1995) International Journal of Immunogenetics, 22 p.443-465
Journal articleDifferential detection of rat islet and brain glutamic acid decarboxylase (GAD) isoforms with sequence-specific peptide antibodies
L. Li, J. Jiang, W. A. Hagopian, A. E. Karlsen, M. Skelly, et al.
(1995) Journal of Histochemistry and Cytochemistry, 43 p.53-59
Journal articleA combinatorial antibody library for the cloning of IDDM-associated autoantibody genes
Alberto Falorni, A Borch, B. Persson, Åke Lernmark
(1995) Diabetes 1994: : Proceedings of the 15th International Diabetes Federation Congress, Kobe, 6-11, November 1994 (International Congress Series) , p.1057-1062
Conference paperEtiology, Pathogenesis, and Natural History of Insulin-Dependent (Type 1) Diabetes.
Åke Lernmark
(1995) Endocrinology
Book chapterIslet cell antibodies are associated with β-cell failure also in obese adult onset diabetic patients
A. Gottsäter, M. Landin-Olsson, Å Lernmark, P. Fernlund, G. Sundkvist
(1994) Acta Diabetologica, 31 p.226-231
Journal articleInheritance of MHC class II genes in IDDM studied in population-based affected and control families
I. Kockum, R. Wassmuth, E. Holmberg, B. Michelsen, Å Lernmark
(1994) Diabetologia, 37 p.1105-1112
Journal articleA novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM
C. E. Grubin, T. Daniels, B. Toivola, M. Landin-Olsson, W. A. Hagopian, et al.
(1994) Diabetologia, 37 p.344-350
Journal articleIslet cell antibodies, but not glutamic acid decarboxylase antibodies, are decreased by plasmapheresis in patients with newly diagnosed insulin-dependent diabetes mellitus
Göran Sundkvist, William A. Hagopian, Mona Landin-Olsson, Åke Lernmark, Lawe Ohlsson, et al.
(1994) Journal of Clinical Endocrinology and Metabolism, 78 p.1159-1165
Journal articleKan insulinberoende diabetes botas? Mer forskning om GAD-autoimmunitet krävs.
A. Lernmark
(1994) Läkartidningen, 91 p.3977-3980
Journal articleRadioimmunoassay detects the frequent occurrence of autoantibodies to the mr 65,000 isoform of glutamic acid decarboxylase in japanese insulin-dependent diabetes
A. Falorni, C. E. Grubin, I. Takei, A. Shimada, A. Kasuga, et al.
(1994) Autoimmunity, 19 p.113-125
Journal articleFailure to detect genomic viral sequences in pancreatic tissues from two children with acute‐onset diabetes mellitus
Javier Buesa‐Gomez, Juan Carlos De LaTorre, Thomas Dyrberg, Mona Landin‐Olsson, Richard S. Mauseth, et al.
(1994) Journal of Medical Virology, 42 p.193-197
Journal articleIdentification of autoantibody epitopes of glutamic acid decarboxylase in Stiff-man syndrome patients
L. Li, W. A. Hagopian, H. R. Brashear, T. Daniels, A. Lernmark
(1994) Journal of Immunology, 152 p.930-934
Journal articleAnalysis of antibody markers, DRB1, DRB5, DQA1 and DQB1 genes and modeling of DR2 molecules in DR2‐positive patients with insulin‐dependent diabetes mellitus
C. B. Sanjeevi, T. P. Lybrand, M. Landin‐Olsson, I. Kockum, G. Dahlquist, et al.
(1994) Tissue Antigens, 44 p.110-119
Journal articleFunctional state of the β cell affects expression of both forms of glutamic acid decarboxylase
Wei Hao, Linsong Li, Vivek Mehta, Åke Lernmark, Jerry P. Palmer
(1994) Pancreas, 9 p.558-562
Journal articleWeight loss in rats following intraventricular transplants of pancreatic islets
R. D. Richardson, D. S. Ramsay, A. Lernmark, A. J.W. Scheurink, D. G. Baskin, et al.
(1994) American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 266
Journal articleHigh level of concordance between assays for glutamic acid decarboxylase antibodies : The First International Glutamic Acid Decarboxylase Antibody Workshop
R S Schmidli, P G Colman, E Bonifacio, G F Bottazzo, L C Harrison
(1994) Diabetes, 43 p.9-1005
Journal articleIslet cell expression and autoimmunity to two isoforms of glutamic acid decarboxylase in relation to insulin-dependent diabetes
A E Karlsen, JS Petersen, William A. Hagopian, TB Rambrandt, N Videbaek, et al.
(1994) Insulin secretion and pancreatic B-cell research , p.499-507
Book chapterDiabetes type 1 med debut i åldrarna 15 till 34 år. Lägesrapport från diabetesincidensstudien i Sverige.
A. Lernmark, J. Ostman
(1993) Läkartidningen, 90 p.3652-3656
Journal articleProtection from bb rat diabetes by the platelet-activating factor inhibitor BN50730
Lance W. Jobe, Roel Ubungen, Charles J. Goodner, Denis G. Baskin, Pierre Braquet, et al.
(1993) Autoimmunity, 16 p.259-266
Journal articleAutoimmune endocrinopathies 3 Islet cell autoimmunity
Å LERNMARK, C. MÖLLER, I. KOCKUM, C. SANJEEVI
(1993) Journal of Internal Medicine, 234 p.361-369
Journal articleProspective evaluation of β-cell function in insulin antoantibody-positive relatives of insulin-dependent diabetic patients
James L. Neifing, Carla J. Greenbaum, Steven E. Kahn, David K. McCulloch, Heike Barmeier, et al.
(1993) Metabolism, 42 p.482-486
Journal articleDifferential expression of glutamic acid decarboxylase in rat and human islets
Jacob S. Petersen, Steven Russel, Michael O. Marshall, Hans Kofod, Karsten Buschard, et al.
(1993) Diabetes, 42 p.484-495
Journal articleAutoantibodies in IDDM primarily recognize the 65,000-Mr rather than the 67,000-Mr isoform of glutamic acid decarboxylase
William A. Hagopian, Birgitte Michelsen, Allan E. Karlsen, Fleming Larsen, Alistar Moody, et al.
(1993) Diabetes, 42 p.631-636
Journal articleAnalysis of HLA‐DQA1 and ‐DQB1 genes in Mexican Americans with insulin‐dependent diabetes mellitus
C. B. Sanjeevi, A. Zeidler, S. Shaw, J. Rotter, G. T. Nepom, et al.
(1993) Tissue Antigens, 42 p.72-77
Journal articleHLA-DQ primarily confers protection and HLA-DR susceptibility in type I (insulin-dependent) diabetes studied in population-based affected families and controls
I. Kockum, R. Wassmuth, E. Holmberg, B. Michelsen, A. Lernmark
(1993) American Journal of Human Genetics, 53 p.150-167
Journal articleHLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis
S ‐A Ivarsson, S. ERIKSSON, I. KOCKUM, Å LERNMARK, S. LINDGREN, et al.
(1993) Journal of Internal Medicine, 233 p.281-286
Journal articleQuantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 64K autoantibody positivity at onset predicts diabetes type
William A. Hagopian, Allan E. Karlsen, Anders Gottsäter, Mona Landin-Olsson, Catherine E. Grubin, et al.
(1993) Journal of Clinical Investigation, 91 p.368-374
Journal articleAnalysis of T-cell surface marker profiles during the postnatal ontogeny of normal and diabetes-prone rats
F. Haag, F. Nolte, A. Lernmark, C. Simrell, H. G. Thiele
(1993) Transplantation Proceedings, 25 p.2831-2832
Journal articleDecreased weight gain in BB rats before the clinical onset of insulin-dependent diabetes
Helle Markholst, Susan Eastman, Deborah Wilson, Lloyd Fisher, Åke Lernmark
(1993) Diabetes Research and Clinical Practice, 21 p.31-38
Journal articleMapping of glutamic acid decarboxylase (GAD) genes
Susanne Edelhoff, Catherine E. Grubin, Allan E. Karlsen, David A. Adler, Don Foster, et al.
(1993) Genomics, 17 p.93-97
Journal articleHLA genotypes in coeliac disease and healthy individuals carrying gliadin antibodies
Anna Pettersson, Klas Sjöberg, Åke Lernmark, Sten Eriksson
(1993) European Journal of Gastroenterology and Hepatology, 5 p.445-450
Journal articleβ-cell function in relation to islet cell antibodies during the first 3 yr after clinical diagnosis of diabetes in type II diabetic patients
A. Gottsater, M. Landin-Olsson, P. Fernlund, A. Lernmark, G. Sundkvist
(1993) Diabetes Care, 16 p.902-910
Journal articleHLA DR AND DQ RFLP ANALYSIS IN CROHN'S DISEASE
R. Wassmuth, S. Eastman, I. Kockum, E. Holmberg, M. Starck, et al.
(1993) International Journal of Immunogenetics, 20 p.429-433
Journal articleRegulation of glutamic acid decarboxylase diabetes autoantigen expression in highly purified isolated islets from Macaca nemestrina
W A Hagopian, A E Karlsen, J S Petersen, J Teague, A Gervassi, et al.
(1993) Endocrinology, 132 p.81-2674
Journal articleIslet cell antibodies and fasting plasma C-peptide during the first 10 yr after diagnosis in patients with diabetes mellitus diagnosed in adult age
A. Gottsater, U. Samuelsson, S. Nilsson, A. Lernmark, G. Sundkvist
(1992) Diabetes, Nutrition and Metabolism - Clinical and Experimental, 5 p.243-248
Journal articlePancreatic beta-cell function evaluated by intravenous glucose and glucagon stimulation. A comparison between insulin and c-peptide to measure insulin secretion
A. Gottsäter, M. Landin-Olsson, P. Fernlund, B. Gullberg, Å Lernmark, et al.
(1992) Scandinavian Journal of Clinical and Laboratory Investigation, 52 p.631-639
Journal articleDiabetes and frontiers of research. Introduction.
A. Lernmark, P. J. Morris, A. H. Rubenstein
(1992) Diabetologia, 35
Journal article (comment)Genetic dissection of autoimmune type I diabetes in the BB rat
Howard J. Jacob, Anna Pettersson, Deborah Wilson, Yipei Mao, Åke Lernmark, et al.
(1992) Nature Genetics, 2 p.56-60
Journal articleSequential Injection Immunoassay Utilizing Immunomagnetic Beads
Cy H. Pollema, Jaromir Ruzicka, Gary D. Christian, Åke Lernmark
(1992) Analytical Chemistry, 64 p.1356-1361
Journal articleIslet cell and thyrogastric antibodies in 633 consecutive 15- to 34-yr-old patients in the diabetes incidence study in Sweden
M. Landin-Olsson, F. A. Karlsson, A. Lernmark, G. Sundkvist, H. Arnqvist, et al.
(1992) Diabetes, 41 p.1022-1027
Journal articleRecombinant glutamic acid decarboxylase (representing the single isoform expressed in human islets) detects IDDM-associated 64,000-Mr autoantibodies
Allan E. Karlsen, William A. Hagopian, Jacob S. Petersen, Esper Boel, Thomas Dyrberg, et al.
(1992) Diabetes, 41 p.1355-1359
Journal articleIn vivo effects of interleukin-1/β on blood leukocytes in bb rats prone or resistant to diabetes
Lance W. Jobe, Sarah Vertrees, Cindy A. Wilson, Cindy Jacobs, Deborah L. Wilson, et al.
(1992) Autoimmunity, 11 p.233-237
Journal articleImproved specificity of ICA assays in the Fourth International Immunology of Diabetes Serum Exchange Workshop
C. J. Greenbaum, J. P. Palmer, S. Nagataki, Y. Yamaguchi, J. L. Molenaar, et al.
(1992) Diabetes, 41 p.1570-1574
Journal articleQuantitative analysis of islet glutamic acid decarboxylase p64 autoantibodies in insulin-dependent diabetes mellitus
Heike Bärmeier, Jarl Ahlmén, Mono Landin-Olsson, Ray V. Rajotte, Göran Sundkvist, et al.
(1992) Autoimmunity, 13 p.187-196
Journal articleFlow-injection immunoassays : Present and future
Cy H. Pollema, Jaromir Ruzicka, Åke Lernmark, Gary D. Christian
(1992) Microchemical Journal, 45 p.121-128
Journal articlePredictive value of islet cell and insulin autoantibodies for type 1 (insulin-dependent) diabetes mellitus in a population-based study of newly-diagnosed diabetic and matched control children
M Landin-Olsson, J P Palmer, A Lernmark, L Blom, G Sundkvist, et al.
(1992) Diabetologia, 35 p.73-1068
Journal articleAutoimmune diabetes mellitus
W Hagopian, Å Lernmark
(1992) Autoimmune diseases II , p.235-278
Book chapterAetiology of type I diabetes: genetic aspects
R Wassmuth, I Kockum, A. Karlsen, W Hagopian, H Barmeier, et al.
(1992) Insulin, Molecular Biology to Pathology , p.285-305
Book chapterCloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10
Allan E. Karlsen, William A. Hagopian, Catherine E. Grubin, Syamalima Dube, Christine M. Disteche, et al.
(1991) Proceedings of the National Academy of Sciences of the United States of America, 88 p.8337-8341
Journal articleRisk for developing Type 1 (insulin-dependent) diabetes mellitus and the presence of islet 64K antibodies
H. Bärmeier, D. K. McCulloch, J. L. Neifing, G. Warnock, R. V. Rajotte, et al.
(1991) Diabetologia, 34 p.727-733
Journal articleAutoimmunity of diabetes
A. Lernmark, H. Barmeier, S. Dube, W. Hagopian, A. Karlsen, et al.
(1991) Endocrinology and Metabolism Clinics of North America, 20
Journal article reviewEffects of sodium butyrate on proliferation-dependent insulin gene expression and insulin release in glucose-sensitive RIN-5AH cells
A. E. Karlsen, W. Y. Fujimoto, P. Rabinovitch, S. Dube, A. Lernmark
(1991) Journal of Biological Chemistry, 266 p.7542-7548
Journal articleThe Fourth International Serum Exchange Workshop to standardize cytoplasmic islet cell antibodies
Å Lernmark, J. L. Molenaar, W. A.M. van Beers, Y. Yamaguchi, S. Nagataki, et al.
(1991) Diabetologia, 34 p.534-535
Journal article (comment)Diabetes segregates as a single locus in crosses between inbred BB rats prone or resistant to diabetes
Helle Markholst, Susan Eastman, Deborah Wilson, Bodil E. Andreasen, Åke Lernmark
(1991) Journal of Experimental Medicine, 174 p.297-300
Journal articleHuman cell lines from families available for diabetes research
Å Lernmark
(1991) Diabetologia, 34
Journal article (letter)Relating homology between the Epstein-Barr virus BOLF1 molecule and HLA-DQw8 β chain to recent onset Type 1 (insulin-dependent) diabetes mellitus
T. Sairenji, M. Daibata, C. H. Sorli, H. Qvistbäck, R. E. Humphreys, et al.
(1991) Diabetologia, 34 p.33-39
Journal articleInterleukin-1β regulation of islet and thyroid autoimmunity in the BB rat
Sarah Vertrees, Cindy A. Wilson, Roel Ubungen, Deborah Wilson, Denis G. Baskin, et al.
(1991) Journal of Autoimmunity, 4 p.717-732
Journal articleIslet Cell Cytoplasmic Antibodies (ICA) in Diabetes and Disorders of Glucose Tolerance
B. Marner, G. Bille, M. Christy, E. M. Damsgaard, S. Garne, et al.
(1991) Diabetic Medicine, 8 p.812-816
Journal articleIslet cell antibody reactivity with human fetal pancreatic islets
Göran Sundkvist, Agneta Bergqvist, Henrik Weibull, David Bergqvist, Kaj Fält, et al.
(1991) Diabetes Research and Clinical Practice, 14 p.1-7
Journal articleLeukocytosis at the onset of diabetes in crosses of inbred BB rats
Susan Eastman, Helle Markholst, Deborah Wilson, Åke Lernmark
(1991) Diabetes Research and Clinical Practice, 12 p.113-123
Journal articleEffects of ginkgolide b, a platelet-activating factor inhibitor on insulitis in the spontaneously diabetic bb rat
Jill C. Beck, Charles J. Goodner, Cindy Wilson, Deborah Wilson, Dave Glidden, et al.
(1991) Autoimmunity, 9 p.225-235
Journal articleAssessment of precision, concordance, specificity, and sensitivity of islet cell antibody measurement in 41 assays
E. Bonifacio, C. Boitard, H. Gleichmann, M. A. Shattock, J. L. Molenaar, et al.
(1990) Diabetologia, 33 p.731-736
Journal articleHLA-DQ and -DX genes in insulin-dependent diabetes mellitus
B. Michelsen, T. Dyrberg, H. Vissing, P. Serup, A. Lernmark
(1990) Current Topics in Microbiology and Immunology, 164 p.57-68
Journal article reviewIslet cell antibodies and fasting C-peptide predict insulin requirement at diagnosis of diabetes mellitus
M. Landin-Olsson, K. O. Nilsson, Å Lernmark, G. Sundkvist
(1990) Diabetologia, 33 p.561-568
Journal articleIL-1β modulation of spontaneous autoimmune diabetes and thyroiditis in the BB rat
C. A. Wilson, C. Jacobs, P. Baker, D. G. Baskin, S. Dower, et al.
(1990) Journal of Immunology, 144 p.3784-3788
Journal articleA novel affinity purification method to isolate peptide specific antibodies
Allan Karlsen, Åke Lernmark, Hans Kofod, Thomas Dyrberg
(1990) Journal of Immunological Methods, 128 p.151-157
Journal articleCellular and subcellular localization of an M(r) 64,000 protein autoantigen in insulin-dependent diabetes
M. R. Christie, D. G. Pipeleers, A. Lernmark, S. Baekkeskov
(1990) Journal of Biological Chemistry, 265 p.376-381
Journal articleLack of systematically found insulin autoantibodies in spontaneously diabetic BB rats
Helle Markholst, Leslie J. Klaff, Günter Klöppel, Åke Lernmark, John P. Mordes, et al.
(1990) Diabetes, 39 p.720-727
Journal articleHLA Heterozygosity in Insulin‐Dependent Diabetes is Most Frequent at the DQ Locus
B. MICHELSEN, R. WASSMUTH, J. LUDVIGSSON, LERNMARK, G. T. NEPOM, et al.
(1990) Scandinavian Journal of Immunology, 31 p.405-413
Journal articleImmunoreactive trypsin(Ogen) in the sera of children with recent-onset insulin-dependent diabetes and matched controls
Mona Landin-Olsson, Anders Borgstrom, Leif Blom, Goran Sundkvist, Ake Lernmark, et al.
(1990) Pancreas, 5 p.241-247
Journal articleA novel microwell indirect immunofluorescence assay to detect antibodies against islet cell surface antigens in insulin-dependent diabetes mellitus.
I. Matsuba, A. Lernmark
(1990) Regional Immunology, 3 p.23-28
Journal articleMolecular analysis of the pathogenesis of β-cell destruction in insulin-dependent diabetes mellitus
A. Lernmark, H. Barmeier, S. Dube, W. Hagopian, A. E. Karlsen, et al.
(1990) Western Journal of Medicine, 153 p.499-502
Journal article (comment)The humoral anti-islet response. II. Biochemical studies
H Barmeier, M Christie, B. Herold, KC Herold, Å Lernmark
(1990) Endocinology and metabolism: progress in research and clinical practice, 4 p.87-104
Book chapterPathophysiology of type I (insulin-dependent) diabetes
J Palmer, Å Lernmark
(1990) Diabetes mellitus : theory and practice , p.414-435
Book chapterPostimmunization activity of oligoadenylate synthetase in peripheral blood lymphocytes from healthY individuals
V. Bonnevie-Nielsen, I. Heron, T. Kristensen, B. Michelsen, A. Lernmark
(1989) Journal of Clinical and Laboratory Immunology, 28 p.155-160
Journal articleGenes and gene products in the development of diabetes mellitus : Concluding remarks
A. Lernmark
(1989) Genes and gene products in the development of diabetes mellitus : proceedings of the 3rd Nordisk Insulin Symposium 'Genes ane gene products in the development of diabetes mellitus'. ICS866 , p.421-428
Conference paperIslet cell and other organ-specific autoantibodies in all children developing Type 1 (insulin-dependent) diabetes mellitus in Sweden during one year and in matched control children
M. Landin-Olsson, A. Karlsson, G. Dahlquist, L. Blom, Å Lernmark, et al.
(1989) Diabetologia, 32 p.387-395
Journal articlePatogenesen ved type 1 diabetes.
T. Dyrberg, W. Hansen, A. Lernmark
(1989) Ugeskrift for Laeger, 151 p.1029-1030
Journal articleSupravital dithizone staining in the isolation of human and rat pancreatic islets
W. A. Hansen, M. R. Christie, R. Kahn, A. Norgaard, I. Abel, et al.
(1989) Diabetes Research, 10 p.53-57
Journal articleIncreased levels of circulating immune complexes are not associated with diabetes in BB rats
G. Contreas, T. Dyrberg, O. D. Madsen, H. Markholst, A. Lernmark
(1989) Diabetes Research, 10 p.109-113
Journal articleSite-specific antibodies distinguish single amino acid substitutions in position 57 in HLA-DQ β-chain alleles associated with insulin-dependent diabetes
D. Atar, T. Dyrberg, B. Michelsen, A. Karlsen, H. Kofod, et al.
(1989) Journal of Immunology, 143 p.533-538
Journal articleThe genetics of susceptibility to diabetes
Ralf Wassmuth, Åke Lernmark
(1989) Clinical Immunology and Immunopathology, 53 p.358-399
Journal articleAssociation of IDDM and attenuated response of 2',5'-oligoadenylate synthetase to yellow fever vaccine
V. Bonnevie-Nielsen, M. L. Larsen, J. J. Frifelt, B. Michelsen, A. Lernmark
(1989) Diabetes, 38 p.1636-1642
Journal articleInsulitis and diabetes are preceded by a decrease in β cell volume in diabetes-prone bb rats
M. Löhr, H. Markholst, T. Dyrberg, G. Klöppel, M. Oberholzer, et al.
(1989) Pancreas, 4 p.95-100
Journal articleMultiple growth hormone-binding proteins are expressed on insulin-producing cells
Annette Møldrup, Nils Billestrup, Niels A. Thorn, Åke Lernmark, Jens Høiriis Nielsen
(1989) Molecular Endocrinology, 3 p.1173-1182
Journal articleDerivation of non-lymphopenic BB rats with an intercross breeding
K C Herold, W Kastern, H Markholst, A Lernmark, B Andreason
(1989) Autoimmunity, 3 p.83-93
Journal articleModern Concepts of Diabetes and its Pathogenesis : 13-24
B Michelsen, A Grove, H. Vissing, Hans Kofod, S. Baekkeskov, et al.
(1989) International handbook of pancreas transplantation
Book chapterEtiology, pathogenesis and natural history of insulin-dependent (Type 1) diabetes.
Å Lernmark, J Nerup
(1989) Endocrinology, 3 p.1357-1368
Book chapterImmunologi och autoimmunitet vid insulinberoende (typ I) diabetes.
G. Sundkvist, M. Landin-Olsson, A. Lernmark
(1988) Nordisk medicin, 103 p.340-342
Journal articleGene probes to detect cross-culture contamination in hormone producing cell lines
I. Matsuba, Å Lernmark, B. Michelsen, J. H. Nielsen, J. Scholler, et al.
(1988) In Vitro Cellular & Developmental Biology, 24 p.1071-1076
Journal articleImmunologi och insulinberoende diabetes mellitus--en översikt.
A. Lernmark, M. L. Olsson, G. Sundkvist
(1988) Läkartidningen, 85 p.3175-3179
Journal articleFactors influencing the magnitude, duration, and rate of fall of B-cell function in Type 1 (insulin-dependent) diabetic children followed for two years from their clinical diagnosis
M. Wallensteen, G. Dahlquist, B. Persson, M. Landin-Olsson, Å Lernmark, et al.
(1988) Diabetologia, 31 p.664-669
Journal articleAntibodies to a Mr-64000 islet cell protein in Swedish children with newly diagnosed Type 1 (insulin-dependent) diabetes
M. Christie, M. Landin-Olsson, G. Sundkvist, G. Dahlquist, Å Lernmark, et al.
(1988) Diabetologia, 31 p.597-602
Journal articleHow do I get that abstract accepted?
Åke Lernmark
(1988) Diabetologia, 31 p.455-456
Journal article (letter)Serum exchange and use of dilutions have improved precision of measurement of islet cell antibodies
E. Bonifacio, A. Lernmark, R. L. Dawkins, co-authors
(1988) Journal of Immunological Methods, 106 p.83-88
Journal articleTissue-specific expression of transfected human insulin genes in pluripotent clonal rat insulinoma lines induced during passage in vivo
O. D. Madsen, L. C. Andersen, B. Michelsen, D. Owerbach, L. I. Larsson, et al.
(1988) Proceedings of the National Academy of Sciences of the United States of America, 85 p.6652-6656
Journal articleSecretion uncouples glucose inhibition of glucagon-producing cells resulting in a simultaneous stimulation of both glucagon and insulin release
Hans Kofod, Jens J. Holst, Åke Lernmark
(1988) Regulatory Peptides, 23 p.315-322
Journal articleInsulin release by glucagon and secretin : studies with secretin-glucagon hybrids
H. Kofod, D. Andreu, P. Thams, R. B. Merrifield, C. J. Hedeskov, et al.
(1988) American Journal of Physiology - Endocrinology and Metabolism, 254 p.454-458
Journal articleNonislet pancreatic autoantibodies in sibship with permanent neonatal insulin-dependent diabetes mellitus
S. A. Ivarsson, B. Marner, A. Lernmark, K. O. Nilsson
(1988) Diabetes, 37 p.347-350
Journal articleInterleukin-1 potentiates glucose stimulated insulin release in the isolated perfused pancreas
L. D. Wogensen, T. Mandrup-Poulsen, H. Markholst, J. Molvig, A. Lernmark, et al.
(1988) Acta Endocrinologica, 117 p.302-306
Journal articleReduced pancreatic insulin is associated with retarded growth of the pancreas in young prediabetic BB rats
H. Markholst, Å Lernmark
(1988) Pancreas, 3 p.140-144
Journal articleEtudes sur les diabètes spontanés et induits par la streptozotocine chez le rat et la souris.
A. Lernmark, H. Markholst, H. Laursen, G. Contreas, M. Altieri, et al.
(1988) Journees annuelles de diabetologie de l"Hotel-Dieu , p.15-31
Journal article reviewIslet β-cytotoxic monoclonal antibody against glycolipids in experimental diabetes induced by low dose streptozotocin and Freund's adjuvant
M. Ziegler, S. Teneberg, S. Witt, B. Ziegler, B. Hehmke, et al.
(1988) Journal of Immunology, 140 p.4144-4150
Journal articleEpidemiological and genetic aspects on islet autoimmunity in childhood insulin-dependent diabetes.
M Landin-Olsson, L Blom, G. Dahlquist, Å Lernmark, B Michelsen, et al.
(1988) Genetic susceptibility to environmental factors : a challenge for public intervention : [First International Ernhold Lundström Symposium, Malmö, Sweden, May 14-16, 1987] , p.87-93
Book chapterMHC Class II antigen fragment length polymorphism in Type I (insulin-dependent) diabetes
B. Michelsen, H. Vissing, M Feldman, Å Lernmark
(1988) Immunogenetics of Endocrine Disorders. , p.203-221
Book chapterCirculating signs of autoimmune islet disease
Å Lernmark, H Markholst, S. Baekkeskov
(1988) The Pathology of the endocrine pancreas in diabetes , p.53-70
Book chapterSpontaneously diabetic BB rats have age-dependent islet β-cell-specific surface antibodies at clinical onset
D. Pipeleers, M. Van De Winkel, T. Dyrberg, A. Lernmark
(1987) Diabetes, 36 p.1111-1115
Journal articlePancreatic antibodies as a marker for pancreatic graft rejection
M. Landin-Olsson, G. Sundkvist, A. Lernmark, H. Weibull, R. Takolander, et al.
(1987) Transplantation Proceedings, 19 p.3890-3891
Journal articleO-cellsantikroppar hos diabetesbarn i Sverige - en preliminär rapport.
M. Landin, G. Sundkvist, A. Lernmark, G. Dahlquist, L. Blom, et al.
(1987) Läkartidningen, 84 p.2038-2040
Journal articleProlonged incubation in the two-colour immunofluorescence test increases the prevalence and titres of islet cell antibodies in Type 1 (insulin-dependent) diabetes mellitus
M. Landin Olsson, G. Sundkvist, Å Lernmark
(1987) Diabetologia, 30 p.327-332
Journal articleImmunology and Diabetes Workshops : Report of the Second International Workshop on the Standardisation of Cytoplasmic Islet Cell Antibodies - Summary of a Workshop organised by the Immunology and Diabetes Workshops Committee, supported in part by the Juvenile Diabetes Foundation International, and held at the "Science at Sea - 1987" meeting in Perth, Western Australia, from 20-22 January
E. Bonifacio, R. L. Dawkins, Å Lernmark
(1987) Diabetologia, 30
Journal article (comment)Autoimmune Aspects of Insulin-Dependent Diabetes Mellitus
Birgitte Michelsen, Steinunn Bækkeskov, Betsy Herold, Michael Christie, Åke Lernmark
(1987) Journal of the Japan Diabetes Society, 30 p.1077-1085
Journal articleMolecular cloning of a polymorphic DNA endonuclease fragment associates insulin-dependent diabetes mellitus with HLA-DQ
B. Michelsen, A. Lernmark
(1987) Journal of Clinical Investigation, 79 p.1144-1152
Journal articleDetection of islet cell autoantibodies in newly diagnosed diabetic patients using insulin-producing Syrian hamster cells.
I. Matsuba, B. Marner, J. Nerup, A. Lernmark
(1987) Diabetes Research, 4 p.103-107
Journal articleIslet‐specific immune mechanisms
ÅKe Lernmark, Shen Li, Steinunn Bækkeskov, Michael Christie, Birgitte Michelsen, et al.
(1987) Diabetes/Metabolism Reviews, 3 p.959-980
Journal articleAntibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes
S Baekkeskov, M Landin, J K Kristensen, S Srikanta, G J Bruining, et al.
(1987) Journal of Clinical Investigation, 79 p.34-926
Journal articleEffects of growth hormone on the endocrine pancreas
J Höiriis Nielsen, Ake Lernmark, OD Madsen, B S Welinder, S Linde, et al.
(1987) International congess series , p.140-160
Book chapterAutoimmunity in diabetes
Helle Markholst, Å Lernmark
(1987) Development in medical virology , p.111-124
Book chapterA deletion in a rat major histocompatibility complex class I gene is linked to the absence of β2-microglobulin-containing serum molecules
L. Bjorck, I. Kryspin-Sorensen, T. Dyrberg, A. Lernmark, W. Kastern
(1986) Proceedings of the National Academy of Sciences of the United States of America, 83 p.5630-5633
Journal articleA simple assay for the detection of antibodies to endocrine islet cell surface antigens
Giovanna Contreas, Ole D. Madsen, Henrik Vissing, Åke Lernmark
(1986) Journal of Immunological Methods, 95 p.135-139
Journal articleIslet cell and 64k autoantibodies are associated with plasma IgG in newly diagnosed insulin-dependent diabetic children
I. Gerling, S. Baekkeskov, A. Lernmark
(1986) Journal of Immunology, 137 p.3782-3785
Journal articleCloned cell lines from a transplantable islet cell tumor are heterogeneous and express cholecystokinin in addition to islet hormones
O. D. Madsen, L. I. Larsson, J. F. Rehfeld, T. W. Schwartz, A. Lernmark, et al.
(1986) Journal of Cell Biology, 103 p.2025-2034
Journal articlePanel discussion I : diagnosis, classification, and value of screening for diabetes mellitus.
L. Jarett, J. S. Soeldner, A. Lernmark, R. A. Rizza, J. Santiago
(1986) Clinical Chemistry, 32
Journal articleInsulin release and pancreatic insulin is reduced in young prediabetic BB rats
A. Svenningsen, T. Dyrberg, H. Markholst, C. Binder, A. Lernmark
(1986) Acta Endocrinologica, 112 p.367-371
Journal articleIslet cell and other organ-specific autoantibodies in healthy first-degree relatives to insulin-dependent
B. Hagglof, A. Rabinovitch, P. Mackay, A. Huen, A. H. Rubenstein, et al.
(1986) Acta Paediatrica Scandinavica, 75 p.611-618
Journal articleAntibodies to an Mr 64,000 Human Islet Cell Protein in the Prediabetic Period of IDDM Patients
S. BAKKESKOV, J. BRUINING, S. SRIKANTA, T. MANDRUP, C. DE BEAUFORT, et al.
(1986) Annals of the New York Academy of Sciences, 475 p.415-417
Journal articlePotentiation of insulin release in response to amino acid methyl esters correlates to activation of islet glutamate dehydrogenase activity
H. Kofod, A. Lernmark, C. J. Hedeskov
(1986) Acta Physiologica Scandinavica, 128 p.335-340
Journal articleSecretin and its C-terminal hexapeptide potentiates insulin release in mouse islets
H. Kofod, B. Hansen, A. Lernmark, C. J. Hedeskov
(1986) American Journal of Physiology - Endocrinology and Metabolism, 250 p.107-113
Journal articleAn H-2 alloantiserum preserves β-cell function in mice made diabetic by low-dose streptozotocin
V. Bonnevie-Nielsen, A. Lernmark
(1986) Diabetes, 35 p.570-573
Journal articleMonoclonal Antibodies against Pancreatic Islet‐Cell‐Surface Antigens Selected by Flow Cytofluorometry
H. VISSING, G. PAPADOPOULOS, LERNMARK
(1986) Scandinavian Journal of Immunology, 23 p.425-433
Journal articleA two-colour immunofluorescence test with a monoclonal human proinsulin antibody improves the assay for islet cell antibodies
O D Madsen, M Landin Olsson, G Bille, G Sundkvist, A Lernmark, et al.
(1986) Diabetologia, 29 p.8-115
Journal articleLong-term effect of plasmapheresis in the initial treatment of IDDM in children
J Ludvigsson, L. Heding, G. Lieden, B. Marner, Ake Lernmark
(1986) Future Trends in Juvenile Diabetes : 6th International Beilinson Symposium, Herzliya-on-Sea, October 1984: Proceedings , p.355-361
Conference paperIslet cell antibodies
S. BAKKESKOV, M Christie, Å Lernmark
(1986) Immunology of endocrine diseases , p.73-88
Book chapterHLA-DQ gene polymorphism in insulin-dependent diabetes
B. Michelsen, Ake Lernmark
(1986) International congress series , p.3-8
Book chapterInsulin-dependent diabetes mellitus
Å Lernmark, S. Baekkeskov
(1986) Clinical Diabetes Mellitus , p.26-39
Book chapterIsolation of a rat immune response gene identical to an alleged mouse A class II β-chain pseudogene
Jørgen Schøller, Åke Lernmark
(1985) Immunogenetics, 22 p.601-608
Journal articleIncreased reduction in fasting C-peptide is associated with islet cell antibodies in Type 1 (insulin-dependent) diabetic patients
B. Marner, T. Agner, C. Binder, Å Lernmark, J. Nerup, et al.
(1985) Diabetologia, 28 p.875-880
Journal articleMécanisme et contrôle génétique de la réponse auto-immune dirigée contre les cellules bêta-pancréatiques au cours du diabète insulinodépendant.
B. Michelsen, S. Baekkeskov, T. Deufel, W. Kastern, H. Kofod, et al.
(1985) Journees annuelles de diabetologie de l"Hotel-Dieu , p.171-182
Journal article reviewIslet cell antibodies in insulin-dependent (type 1) diabetic children treated with plasmapheresis
B. Marner, A. Lernmark, J. Ludvigsson, P. MacKay, I. Matsuba, et al.
(1985) Diabetes Research, 2 p.231-236
Journal articleLocus-specific detection of HLA-DQ and -DR antigens by antibodies against synthetic N-terminal octapeptides of the β chain
Thomas Deufel, Anne Grove, Hans Kofod, Åke Lernmark
(1985) FEBS Letters, 189 p.329-337
Journal articleMolecular biology of Type 1 (insulin-dependent) diabetes mellitus
Å Lernmark
(1985) Diabetologia, 28 p.195-203
Journal article reviewImmunological aspects of type 1 and 2 diabetes mellitus.
A. Lernmark, S. Baekkeskov, I. Gerling, W. Kastern, C. Knutson, et al.
(1985) Advances in Experimental Medicine and Biology, 189 p.107-127
Book chapterDiffusion of C-peptide but not proinsulin from islets in frozen sections of human pancreas identified by monoclonal antibodies
O. D. Madsen, L. I. Larsson, A. Lernmark
(1985) Biomedica Biochimica Acta, 44 p.133-136
Journal articleImmune complexes in insulin-dependent diabetes
G. Contreas, A. Lernmark, E. R. Mathiesen, T. Deckert
(1985) Biomedica Biochimica Acta, 44 p.129-132
Journal articleIdentification of an HLA-DQ β-chain related genomic sequence associated with insulin-dependent diabetes
B. Michelsen, W. Kastern, A. Lernmark, D. Owerbach
(1985) Biomedica Biochimica Acta, 44 p.33-36
Journal articleCortisone fails to affect levels of islet cell surface antibodies and incidence of diabetes in the BB rat
T. Dyrberg, J. King, Lernmark, J. M. Martin
(1985) Endocrinology, 116 p.47-50
Journal articleIslet cell antibodies and cellular immunity in human diabetes.
G. Papadopoulos, A. Lernmark
(1984) Behring Institute Mitteilungen , p.50-57
Journal article reviewA β-cell glycoprotein of Mr 40 000 is the major rat islet cell immunogen following xenogenic immunisation
S. Bækkeskov, Å Lernmark
(1984) Diabetologia, 27 p.70-73
Journal articleSpontaneous in vitro immunoglobulin secretion at the diagnosis of insulin-dependent diabetes
G. Papadopoulos, J. Petersen, V. Andersen, A. Lernmark, B. Marner, et al.
(1984) Acta Endocrinologica, 105 p.521-527
Journal articleIslet cell surface and lymphocyte antibodies often precede the spontaneous diabetes in the BB rat
T. Dyrberg, P. Poussier, F. Nakhooda, E. B. Marliss, Å Lernmark
(1984) Diabetologia, 26 p.159-165
Journal articleA prospective analysis of islet-cell cytotoxic antibodies in insulin-dependent diabetic children. Transient effects of plasmapheresis
A. Rabinovitch, P. MacKay, J. Ludvigsson, A. Lernmark
(1984) Diabetes, 33 p.224-228
Journal articleIn vitro lymphocyte recognition of islet cells following in vivo priming with allogeneic murine pancreatic islets
J. Scott, P. G. MacKay, A. Lernmark
(1984) Acta Endocrinologica, 105 p.87-92
Journal articleIs there an autoimmune component in insulin-dependent diabetes?
A. Lernmark
(1984) Practical Cardiology, 10 p.145-166
Journal articleThe immune response in individuals with hla-dr specificities conferring susceptibility to insulin-dependent diabetes - A hypothesis
G. Papadopoulos, A. Lernmark
(1984) Diabetes Research, 1 p.3-11
Journal article reviewAutoantibodies to a 64-kilodalton islet cell protein precede the onset of spontaneous diabetes in the BB rat
Steinunn Baekkeskov, Thomas Dyrberg, Å K.E. Lernmark
(1984) Science, 224 p.1348-1350
Journal articleSusceptibility to insulin-dependent diabetes defined by restriction enzyme polymorphism of HLA-D region genomic DNA
D. Owerbach, B. Hagglof, A. Lernmark, G. Holmgren
(1984) Diabetes, 33 p.958-965
Journal articleIsolation of islets from mice and rats
J Brunstedt, JH Nielsen, Å Lernmark
(1984) Methods in Diabetes Research : Laboratory methods part C, 1 p.245-248
Book chapterHumoral abnormalities in type I (insulin-dependent) diabetes Mellitus
KC Herold, A-H J Huen, AH Rubenstein, Å Lernmark
(1984) Immunology in diabetes , p.105-120
Book chapterPathogenesis of Type I diabetes mellitus
Å Lernmark, S. Baekkeskov, T Dyrberg, I Gerling, B. Marner, et al.
(1984) International congress series , p.92-96
Book chapterPreparation of islet cell suspensions
Å Lernmark, Thomas Dyrberg, JH Nielsen
(1984) Methods in diabetes research : Laboratory methods, part C, 1 p.259-265
Book chapterImmunological Investigations : islet cell antibodies
B. Marner, C Knutsson, Ake Lernmark, J Nerup
(1984) Methods in Diabetes Research : Laboratory Methods, Part C, 1 p.181-194
Book chapterCell-mediated immunity in Type-I (insulin-dependent) diabetes
Ake Lernmark
(1984) Immunology in diabetes , p.121-131
Book chapterHuman class II major histocompatibility antigen β-chains are derived from at least three loci
Jan Böhme, David Owerbach, Maurizio Denaro, Åke Lernmark, Per A. Peterson, et al.
(1983) Nature, 301 p.82-84
Journal article (letter)Role of islet cell antibodies in the pathogenesis of type I diabetes.
C. H. Brogren, S. Baekkeskov, T. Dyrberg, A. Lernmark, B. Marner, et al.
(1983) Current problems in clinical biochemistry, 12 p.65-85
Journal article reviewHLA-D region β-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals
David Owerbach, Åke Lernmark, Per Platz, Lars P. Ryder, Lars Rask, et al.
(1983) Nature, 303 p.815-817
Journal article (letter)Analysis of islet cell antibodies on frozen sections of human pancreas
B. Marner, Å Lernmark, J. Nerup, J. L. Molenaar, C. W. Tuk, et al.
(1983) Diabetologia, 25 p.93-96
Journal articleGlucose stimulates the biosynthesis of a human pancreatic islet cell protein detected by an antiserum against the human erythrocyte glucose transporter
Steinunn Bækkeskov, Åke Lernmark
(1983) FEBS Letters, 157 p.331-335
Journal articleQuantitative determination of islet cell surface antibodies using 125I-protein A
A. H.J. Huen, M. Haneda, Z. Freedman, A. Lernmark, A. H. Rubenstein
(1983) Diabetes, 32 p.460-465
Journal articlePlasmapheresis in the initial treatment of insulin-dependent diabetes mellitus in children
J. Ludvigsson, L. Heding, G. Lieden, B. Marner, A. Lernmark
(1983) British Medical Journal, 286 p.176-178
Journal article[24] Preparation of Stable Radioiodinated Polypeptide Hormones and Proteins Using Polyacrylamide Gel Electrophoresis
Susanne Linde, Bruno Hansen, Lernmark
(1983) Methods in Enzymology, 92 p.309-335
Journal articleInhibition of insulin release after passive transfer of immunoglobulin from insulin-dependent diabetic children to mice
Annette Svenningsen, Thomas Dyrberg, Ivan Gerling, Åke Lernmark, Peter Mackay, et al.
(1983) Journal of Clinical Endocrinology and Metabolism, 57 p.1301-1304
Journal articleL-Leucine methyl ester stimulates insulin secretion and islet glutamate dehydrogenase
P. Knudsen, H. Kofod, A. Lernmark, C. J. Hedeskov
(1983) American Journal of Physiology - Endocrinology and Metabolism, 245 p.338-346
Journal articleDetection of HLA-D/DR-related DNA polymorphism in HLA-D homozygous typing cells.
D. Owerbach, A. Lernmark, L. Rask, P. A. Peterson, P. Platz, et al.
(1983) Proceedings of the National Academy of Sciences of the United States of America, 80 p.3758-3761
Journal articleβ-cell function relative to islet volume and hormone content in the isolated perfused mouse pancreas
V. Bonnevie Nielsen, Lene Theil Skovgaard, Lernmark
(1983) Endocrinology, 112 p.1049-1056
Journal articleB‐Cell Function and Islet Cell and Other Organ‐Specific Autoantibodies in Relatives to Insulin‐Dependent Diabetic Patients
G. Nordén, E. Jensen, I. Stilbo, G. F. Bottazzo, Lernmark
(1983) Acta Medica Scandinavica, 213 p.199-203
Journal articleIsolation of rat major histocompatibility genes expressed in pancreatic β-cells
W. H. Kastern, A. Lernmark, L. Lyngsie
(1983) Acta Biologica et Medica Germanica, 41 p.1135-1138
Journal articleHumoral immunity in the spontaneously diabetic BB rat
Thomas Dyrberg, Philippe Poussier, Azima F. Nakhooda, Errol B. Marliss, Ake Lernmark
(1983) Metabolism, 32 p.87-91
Journal articleInsulin release from mouse islets perifused with serum IgG from newly insulin-dependent diabetics
M. Ziegler, Å Lernmark
(1983) Acta Biologica et Medica Germanica, 41 p.1123-1127
Journal articleIslet cell surface antibodies in spontaneously diabetic BB rats
T. Dyrberg, A. Lernmark, H. K. Oie, A. F. Gazdar
(1983) Acta Biologica et Medica Germanica, 41 p.1105-1109
Journal articleImmunoglobulin from insulin-dependent diabetic children inhibits glucose-induced insulin release
T. Kanatsuna, S. Baekkeskov, A. Lernmark, J. Ludvigsson
(1983) Diabetes, 32 p.520-524
Journal articleRodent islet cell antigens recognized by antibodies in sera from diabetic patients
S. Baekkeskov, A. Lernmark
(1983) Acta Biologica et Medica Germanica, 41 p.1111-1115
Journal articlePreparation of stable radioiodinated polypeptide hormones and proteins using polyacrylamide gel electrophoresis
Susanne Linde, Bruno Hansen, Åke Lernmark
(1983) Methods in enzymology, 92 p.309-335
Book chapterPurification of islets and cells from islets
J Höiriis Nielsen, Åke Lernmark
(1983) Cell separation : methods and selected applications, 2 p.99-126
Book chapterMetabolic and underlying causes of diabetes mellitus
G. M. Grodsky, C. E. Anderson, D. L. Coleman, J. E. Craighead, G. C. Gerritsen, et al.
(1982) Diabetes, 31 p.45-53
Journal articleAutoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins
Steinunn Baekkeskov, Jens Høiriis Nielsen, Birgitte Marner, Torben Bilde, Johnny Ludvigsson, et al.
(1982) Nature, 298 p.167-169
Journal articleAbsence of H-2 genetic influence on streptozotocin-induced diabetes in mice
H. Kromann, M. Christy, J. Egeberg, Å Lernmark, J. Nerup
(1982) Diabetologia, 23 p.114-118
Journal articleSpecific pancreatic β-cell surface antigens recognized by a xenogenic antiserum
Thomas Dyrberg, Steinunn Baekkeskov, Åke Lernmark
(1982) Journal of Cell Biology, 94 p.472-477
Journal articleThe low dose streptozotocin murine model of Type 1 (insulin-dependent) diabetes mellitus : Studies in vivo and in vitro of the modulating effect of sex hormones
H. Kromann, M. Christy, Å Lernmark, M. Nedergaard, J. Nerup
(1982) Diabetologia, 22 p.194-198
Journal articleNew approaches to therapy and diagnosis of diabetes
B. Hansen, Å Lernmark, J. H. Nielsen, D. Owerbach, B. Welinder
(1982) Diabetologia, 22 p.61-67
Journal article reviewIslet Transplantation in Mice Differing in the I and S Subregions of the H‐2 Complex : Effects of Presensitization with Skin Allografts
J. SCOTT, M. W. STEFFES, A. LERNMARK
(1982) Scandinavian Journal of Immunology, 16 p.9-15
Journal articleSPECIFIC HUMAN PANCREATIC ISLET CELL PROTEINS RECOGNIZED BY ANTIBODIES IN DIABETIC CHILDREN
Steinunn Baekkeskov, Takahiro Kanatsuna, Jens H. Nielsen, Birgitte Marner, Åke Lernmark
(1982) Annals of the New York Academy of Sciences, 392 p.378-378
Journal article6 Islet cell antibodies in diabetes
Carl Henrik Brogren, Ake Lernmark
(1982) Clinics in Endocrinology and Metabolism, 11 p.409-430
Journal articleFlow sorting of mouse pancreatic B cells by forward and orthogonal light scattering
O. Nielsen, J. K. Larsen, I. J. Christensen, Lernmark
(1982) Cytometry, 3 p.177-181
Journal articleEffects of islet cell surface antibodies and complement on the release of insulin and chromium from perifused β cells
T. Kanatsuna, Z. R. Freedman, A. H. Rubenstein, A. Lernmark
(1982) Clinical and Experimental Immunology, 47 p.85-92
Journal articleIslet cell surface antibodies and lymphocyte antibodies in the spontaneously diabetic BB Wistar rat
T Dyrberg, A F Nakhooda, S Baekkeskov, A Lernmark, P Poussier, et al.
(1982) Diabetes, 31 p.81-278
Journal articleSorting of pancreatic islet cell subpopulations by light scattering using a fluorescence-activated cell sorter
D A Nielsen, A Lernmark, M Berelowitz, G D Bloom, D F Steiner
(1982) Diabetes, 31 p.299-306
Journal articleEffects of experimentally induced islet-cell surface antibodies on pancreatic ß cells
T. Kanatsuna, Å Lernmark
(1982) International congress series , p.201-205
Book chapterThe significance of ICSA in IDDM among Caucasians.
S. Baekkeskov, T Dyrberg, T. Kanatsuna, Å Lernmark, I Takei, et al.
(1982) International congress series , p.137-142
Book chapterIslet cell antibodies - Theoretical and practical implications
Å Lernmark, S. Baekkeskov
(1981) Diabetologia, 21 p.431-435
Journal article reviewAn in vitro, sex dependents, and direct cytotoxic effect of streptozotocin on pancreatic islet cells.
H. Kromann, M. Christy, A. Lernmark, J. Nerup
(1981) Hormone and Metabolic Research, 13 p.120-121
Journal articleExpression of major histocompatibility antigens on pancreatic islet cells
S. Baekkeskov, T. Kanatsuna, L. Klareskog, D. A. Nielsen, P. A. Peterson, et al.
(1981) Proceedings of the National Academy of Sciences of the United States of America, 78 p.6456-6460
Journal articleA prospective analysis of antibodies reacting with pancreatic islet cells in insulin-dependent diabetic children
Å Lernmark, B. Hägglöf, Z. Freedman, J. Irvine, J. Ludvigsson, et al.
(1981) Diabetologia, 20 p.471-474
Journal articleLight scattering analysis of rat and mouse islet cells in the fluorescence-activated cell sorter
Å Lernmark, D. A. Nielsen, O. Nielsen, J. K. Larsen
(1981) Upsala Journal of Medical Sciences, 86 p.119-124
Journal articleIslet transplantation in mice differing in the I and S subregions of the H-2 complex
Michael W. Steffes, Otto Nielsen, Thomas Dyrberg, Steinunn Baekkeskov, Joanne Scott, et al.
(1981) Transplantation, 31 p.476-479
Journal articleEffect of diabetes on islet area and β-cell function
V. Bonnevie-Nielsen, A. Lernmark
(1981) Acta Biologica et Medica Germanica, 40 p.77-81
Journal articleBlock in insulin release from column-perifused pancreatic β-cells induced by islet cell surface antibodies and complement
T. Kanatsuna, A. Lernmark, A. H. Rubenstein, D. F. Steiner
(1981) Diabetes, 30 p.231-234
Journal articleA major loss in islet mass and b-cell function precedes hyperglycemia in mice given multiple low doses of streptozotocin
V. Bonnevie-Nielsen, M. W. Steffes, A. Lernmark
(1981) Diabetes, 30 p.424-429
Journal articleAutoimmunity in insulin-dependent diabetes mellitus
Jørn Nerup, Ake Lernmark
(1981) The American journal of medicine, 70 p.135-141
Journal articleIslet cell antibodies
Ake Lernmark, V Bonnevie-Nielsen, S. Baekkeskov, Thomas Dyrberg, T. Kanatsuna, et al.
(1981) Advances in pediatric research , p.61-71
Book chapterOntogenetic patterns of thyrotropin-releasing hormone-like material in rat hypothalamus, pancreas, and retina : Selective effect of light deprivation
E. Martino, H. Seo, A. Lernmark, S. Refetoff
(1980) Proceedings of the National Academy of Sciences of the United States of America, 77 p.4345-4348
Journal articleDirect streptozotocin toxicity on dispersed mouse islet cells determined by [ 51]CR-release
H. Kromann, M. Christy, J. Egeberg, A. Lernmark, J. Nerup, et al.
(1980) Medical Biology, 58 p.322-328
Journal articleCation-activated phosphatase activities in islet cell plasma membrane preparations.
A. Lernmark, D. A. Nielsen, A. U. Parman, J. Sehlin, D. F. Steiner, et al.
(1980) Hormone and Metabolic Research, Supplement, Suppl 10 p.55-61
Journal articleAllogeneic rejection or recurrence of autoimmunity as the cause of immune destruction of pancreatic grafts
R. Gunnarsson, G. F. Bottazzo, Z. R. Freedman, A. Lernmark, H. Zühlke, et al.
(1980) Transplantation Proceedings, 12 p.112-113
Journal articleAntibodies directed against the pancreatic islet cell plasma membrane detection and specificity
Å Lernmark, T. Kanatsuna, C. Patzelt, K. Diakoumis, R. Carroll, et al.
(1980) Diabetologia, 19 p.445-451
Journal articleStable lodinated polypeptide hormones prepared by polyacrylamide gel electrophoresis
Susanne Linde, Bruno Hansen, Åke Lernmark
(1980) Analytical Biochemistry, 107 p.165-176
Journal articleInitial uptake and insulin releasing action of chloromercuribenzene-p-sulphonic acid (CMBS) in suspensions of pancreatic islet cells
L. A. Idahl, A. Lernmark, M. Soderberg, B. Winblad
(1980) Medical Biology, 58 p.101-108
Journal articleAntibodies against endocrine pancreas in insulin-dependent diabetes
A. Lernmark
(1980) Läkartidningen, 77 p.2614-2616
Journal articleSearch for autoimmune reactions against islet tissue in human pancreatic graft recipients.
R. Gunnarsson, C. F. Bottazzo, A. Lernmark, C. G. Groth
(1980) Acta Medica Scandinavica, Supplement, 639 p.639-639
Journal articleCell surface and cytoplasmic islet cell antibodies in insulin-dependent diabetes
Z R Freedman, W J Irvine, Å Lernmark, A-H J Huen, DF Steiner, et al.
(1980) Immunology of diabetes , p.169-175
Book chapterIslet cell, islet cell surface, and insulin antibodies in two pancreatic allotransplant recipients
R Gunnarsson, GF Bottazzo, LG Heding, Å Lernmark, CG Groth
(1980) Proceedings of the Serono Symposia,, 33 p.299-303
Book chapterIslet cell surface antibodies and diabetes mellitus
Å Lernmark, Z R Freedman, T. Kanatsuna, C. Patzelt, AH Rubenstein, et al.
(1980) Immunology of diabetes , p.155-168
Book chapterIslets of Langerhans: an extra hypothalamic source of thyrotropin-releasing hormone in rat pancreas
E Martino, H Seo, Ake Lernmark, S. Refetoff, DF Steiner, et al.
(1980) Serono symposia, 30 p.62-461
Book chapterISLET AUTOANTIBODIES IN HUMAN PANCREATIC TRANSPLANT RECIPIENTS
Rolf Gunnarsson, Carl Gustav Groth, G. Franco Bottazzo, Åke Lernmark
(1979) The Lancet, 313 p.926-926
Journal article (letter)The influence of the major histocompatibility complex (H-2) on experimental diabetes in mice
H. Kromann, Å Lernmark, B. F. Vestergaard, J. Egeberg, J. Nerup
(1979) Diabetologia, 16 p.107-114
Journal articleTrypan Blue as a marker of plasma membrane permeability in alloxan-treated mouse islet cells
K. Grankvist, Lernmark, I. B. Täljedal
(1979) Journal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology, 2 p.139-145
Journal articleA time-dependent correlation exists between loss of β-cell function and islet mass after low-dose streptozotocin
V. Bonnevie-Nielsen, A. Lernmark
(1979) Acta Endocrinologica, 94 p.9-9
Journal article5′-AMP hydrolysis by suspensions and homogenates of pancreatic islet cells from normal and cortisone-treated rats
Å Lernmark, L. A. Söderberg, I. B. Täljedal
(1979) Histochemistry, 63 p.155-161
Journal articleA prospective study of islet cell surface antibodies (ICSA) in insulin-dependent diabetic children
B. Hagglof, G. Holmgren, A. Lernmark, J. Ludvigsson
(1979) Acta Endocrinologica, Supplement, 91 p.36-36
Journal articleCation-dependent phosphatase activities in a rat pancreatic islet plasma membrane fraction prepared by one-step gradient centrifugation
A. Lernmark, D. A. Nielsen, D. F. Steiner
(1979) Journal of Supramolecular and Cellular Biochemistry, 9 p.327-336
Journal articleDetection and possible functional influence of antibodies directed againt the pancreatic islet cell surface.
A. Lernmark, T. Kanatsuna, A. H. Rubenstein, D. F. Steiner
(1979) Advances in Experimental Medicine and Biology, 119 p.157-163
Journal articleIslet cell cytoplasmic and cell surface antibodies in diabetes mellitus
Z R Freedman, C M Feek, W J Irvine, A Lernmark, A H Rubenstein, et al.
(1979) Transactions of the Association of American Physicians, 92 p.64-76
Journal articleIslet-Cell-Surface Antibodies in Juvenile Diabetes Mellitus
Åke Lernmark, Zachary R. Freedman, Cecilia Hofmann, Arthur H. Rubenstein, Donald F. Steiner, et al.
(1978) New England Journal of Medicine, 299 p.375-380
Journal articlePossible toxic effects of normal and diabetic patient serum on pancreatic B-cells
A. Lernmark, J. Sehlin, I. B. Täljedal, H. Kromann, J. Nerup
(1978) Diabetologia, 14 p.25-31
Journal articleHigh concentration of thyrotropin-releasing hormone in pancreatic islets
E Martino, Åke Lernmark, H Seo, D F Steiner, S Refetoff
(1978) Proceedings of the National Academy of Sciences of the United States of America, 75 p.7-4265
Journal articleScanning electron microscopy of surface changes on dispersed pancreatic β-cells following stimulation of insulin release
A. Lernmark, B. Winblad
(1977) Medical Biology, 55 p.141-147
Journal articleImpaired insulin release in isolated islets from mice immunized with homologous pancreatic islets
D. Berggren, A. Lernmark
(1977) Hormone and Metabolic Research, 9 p.430-431
Journal article (comment)Potassium ion-activated hydrolysis of p-nitrophenyl phosphate in pancreatic islet-cell membranes
A. Lernmark, A. Parman, I. B. Taljedal
(1977) Biochemical Journal, 166 p.181-187
Journal articleAlloxan cytotoxicity in vitro : Inhibition of rubidium ion pumping in pancreatic β cells
L. A. Idahl, A. Lernmark, J Sehlin, I. B. Täljedal
(1977) Biochemical Journal, 162 p.9-18
Journal articleFunctional damage to islet cells induced by serum
I. B. Taljedal, A. Lernmark, J. Sehlin
(1977) Acta Endocrinologica, Supplement, 85 p.59-60
Journal articleH 2 influence on experimental diabetes induced by heterologous and homologous immunization and by virus
H. Kromann, A. Lernmark, B. F. Yestergaard
(1977) Acta Endocrinologica, Supplement, 85
Journal articleAlloxan cytotoxicity in vitro : Microscope photometric analyses of trypan blue uptake by pancreatic islet cells in suspension
K. Grankvist, A. Lernmark, I. B. Taljedal
(1977) Biochemical Journal, 162 p.19-24
Journal articleThe pancreatic β cell recognition of insulin secretagogues. XII. Insulin release in response to halogenated hexosamines
B. Hellman, L. A. Idahl, A. Lernmark, I. B. Täljedal, E. W. Thomas
(1976) Molecular Pharmacology, 12 p.208-216
Journal articleEffects of dextran-linked chloromercuribenzoic acid on insulin release from microdissected pancreatic islets
Stig Åkerstrom, Bo Hellman, Åker Lernmark, Bernt Lindberg, Monica Söderberg, et al.
(1976) BBA - General Subjects, 451 p.96-105
Journal articlePreparation and characterization of plasma membrane-enriched fractions from rat pancreatic islets
ÅKe Lernmark, Anne Nathans, Donald F. Steiner
(1976) Journal of Cell Biology, 71 p.606-623
Journal articleStudies on the function of pancreatic islet cell membranes.
L. A. Idahl, A. Lernmark, J. Sehlin, I. B. Täljedal
(1976) Journal de Physiologie, 72 p.729-746
Journal articleOn the possible role of thiol groups in the insulin-releasing action of mercurials, organic disulfides, alkylating agents, and sulfonylureas
B. Hellman, Lernmark, J. Sehlin, M. Söderberg, I. B. Täljedal
(1976) Endocrinology, 99 p.1398-1406
Journal articleScanning electron microscopy of the surface of dispersed B cells in suspension
B. Winblad, A. Lernmark
(1976) Diabetologia, 12 p.279-279
Journal article