My general interest is to understand the mechanisms leading to diabetic complications with the aim to discover potentially targetable pathways involved in the initiation and progression of diabetic complications. My current project explores wheter inhibition of the calcium/calcineurin-sensitive transcription factor Nuclear Factor of Activated T-cells (NFAT) can represent a novel therapeutic modality to restore vascular endothelial function in diabetes. I am also involved in a project that investigates whether blood outgrowth endothelial cells (BOECs) are potential carriers of accessible information about the cardiovascular status of diabetic patients.
Background and techinques/experience
I graduated as a "Doctor of Veterinary Medicine" from the University of Agriculture Faisalabad, Pakistan. I developed a passion for science and obtained a PhD in medical science from Lund University, Sweden in November 2018. The main focus of my doctoral thesis was to develop a genetic model for the risk predicition of recurrent venous thromboembolism.
I have experience of working with pyrosequencing, Sanger´s sequencing, immunohistochemistry, computer image analysis, TaqMan PCR, ELISA, western blot, bio-plex luminex assay, ddPCR and standard molecular biology techniques.
Displaying of publications. Sorted by year, then title.