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WP 1 - Biomarker discovery in observational prospective studies

WP leaders
 

Emma Ahlqvist (as Leif Groops deputy) and Dmytro Kryvokhyzha

Objectives

  • To harmonize available cohort information and sample management
  • To develop a data management system to support joint analysis of distributed data
  • To explore the influence of disease heterogeneity on disease outcome
  • To integrate data on candidate biomarkers & drug targets using systems biology approaches
  • To access and integrate additional data that supports the further validation and refinement of candidate biomarkers and drug targets for diabetes and its complications
  • To generate refined lists of "high quality" validated prognostic/predictive biomarkers or biomarker panels and drug targes that can be prepared for qualification

 

 

 

 

 

 

 

 

 

 

 

 

News

Selcted publications

  • Ahlqvist E et al. Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables. Lancet Diabetes Endocrinol 2018 https://pubmed.ncbi.nlm.nih.gov/29503172/.

Bioinformatics unit
 

More information about the support capabilities and activities of the Bioinformatics Unit
https://www.ludc.lu.se/resources/bioinformatics-unit