WP 1 - Data harmonization and integration
WP leaders
Emma Ahlqvist and Dmytro Kryvokhyzha
Objectives
- To harmonize available cohort information and sample management
- To develop a data management system to support joint analysis of distributed data
- To explore the influence of disease heterogeneity on disease outcome
- To integrate data on candidate biomarkers & drug targets using systems biology approaches
- To access and integrate additional data that supports the further validation and refinement of candidate biomarkers and drug targets for diabetes and its complications
- To generate refined lists of "high quality" validated prognostic/predictive biomarkers or biomarker panels and drug targes that can be prepared for qualification
News
- Paradigm shift in the diagnosis of diabetes, 2018 https://www.ludc.lu.se/article/paradigm-shift-in-the-diagnosis-of-diabetes
Selcted publications
- Ahlqvist E et al. Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables. Lancet Diabetes Endocrinol 2018 https://pubmed.ncbi.nlm.nih.gov/29503172/.
Bioinformatics unit
More information about the support capabilities and activities of the Bioinformatics Unit
https://www.ludc.lu.se/resources/bioinformatics-unit