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Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a six months exercise intervention.

Author:
  • Tina Rönn
  • Petr Volkov
  • Åsa Tornberg
  • Targ Elgzyri
  • Ola Hansson
  • Karl-Fredrik Eriksson
  • Leif Groop
  • Charlotte Ling
Publishing year: 2014
Language: English
Pages: 188-200
Publication/Series: Acta Physiologica
Volume: 211
Issue: 1
Document type: Journal article
Publisher: Wiley-Blackwell

Abstract english

Adipose tissue has an important function in total energy homeostasis and its dysregulation may contribute to life-style related diseases such as type 2 diabetes, cancer and cardiovascular diseases. The aim of this study was to investigate genome-wide mRNA expression in adipose tissue in healthy men before and after an exercise intervention to identify genes or pathways that mediate the beneficial effect of regular exercise. We also investigated the difference in adipose tissue mRNA expression between individuals with or without a family history of type 2 diabetes.

Keywords

  • Physiology

Other

Published
  • Diabetes and Endocrinology
  • Epigenetics and Diabetes
  • Physiotherapy
  • Clinical Vascular Disease Research
  • ISSN: 1748-1708
Tina Rönn
E-mail: tina.ronn [at] med.lu.se

Assistant researcher

Epigenetics and Diabetes

+46 40 39 12 18

CRC 91-12-021

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Lund University Diabetes Centre, CRC, SUS Malmö, Entrance 72, House 91:12. SE-205 02 Malmö. Telephone: +46 40 39 10 00