Lund University is celebrating 350 years. Read more on lunduniversity.lu.se

Menu

Javascript is not activated in your browser. This website needs javascript activated to work properly.
You are here

The prospective association between total and type of fish intake and type 2 diabetes in 8 European countries: EPIC-InterAct Study

Author:
  • Pinal S. Patel
  • Nita G. Forouhi
  • Anneleen Kuijsten
  • Matthias B. Schulze
  • Geertruida J. van Woudenbergh
  • Eva Ardanaz
  • Pilar Amiano
  • Larraitz Arriola
  • Beverley Balkau
  • Aurelio Barricarte
  • Joline W. J. Beulens
  • Heiner Boeing
  • Brian Buijsse
  • Francesca L. Crowe
  • Blandine de Lauzon-Guillan
  • Guy Fagherazzi
  • Paul Franks
  • Carlos Gonzalez
  • Sara Grioni
  • Jytte Halkjaer
  • Jose Maria Huerta
  • Timothy J. Key
  • Tilman Kuehn
  • Giovanna Masala
  • Peter Nilsson
  • Kim Overvad
  • Salvatore Panico
  • Jose Ramon Quiros
  • Olov Rolandsson
  • Carlotta Sacerdote
  • Maria-Jose Sanchez
  • Erik B. Schmidt
  • Nadia Slimani
  • Annemieke M. W. Spijkerman
  • Birgit Teucher
  • Anne Tjonneland
  • Maria-Jose Tormo
  • Rosario Tumino
  • Daphne L. van der A
  • Yvonne T. van der Schouw
  • Stephen J. Sharp
  • Claudia Langenberg
  • Edith J. M. Feskens
  • Elio Riboli
  • Nicholas J. Wareham
Publishing year: 2012
Language: English
Pages: 1445-1453
Publication/Series: American Journal of Clinical Nutrition
Volume: 95
Issue: 6
Document type: Journal article
Publisher: American Society for Clinical Nutrition

Abstract english

Background: Epidemiologic evidence of an association between fish intake and type 2 diabetes (T2D) is inconsistent and unresolved. Objective: The objective was to examine the association between total and type of fish intake and T2D in 8 European countries. Design: This was a case-cohort study, nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) study, with 3.99 million person-years of follow-up, 12,403 incident diabetes cases, and a random subcohort of 16,835 individuals from 8 European countries. Habitual fish intake (lean fish, fatty fish, total fish, shellfish, and combined fish and shellfish) was assessed by country-specific dietary questionnaires. HRs were estimated in each country by using Prentice-weighted Cox regression models and pooled by using a random-effects meta-analysis. Results: No overall association was found between combined fish and shellfish intake and incident T2D per quartile (adjusted HR: 1.00; 95% Cl: 0.94, 1.06; P-trend = 0.99). Total fish, lean fish, and shellfish intakes separately were also not associated with T2D, but fatty fish intake was weakly inversely associated with T2D: adjusted HR per quartile 0.97 (0.94, 1.00), with an HR of 0.84 (0.70, 1.01), 0.85 (0.76, 0.95), and 0.87 (0.78, 0.97) for a comparison of the second, third, and fourth quartiles with the lowest quartile of intake, respectively (P-trend = 0.06). Conclusions: These findings suggest that lean fish, total fish, and shellfish intakes are not associated with incident diabetes but that fatty fish intake may be weakly inversely associated. Replication of these findings in other populations and investigation of the mechanisms underlying these associations are warranted. Meanwhile, current public health recommendations on fish intake should remain unchanged. Am J Clin Nutr 2012;95:1445-53,

Keywords

  • Nutrition and Dietetics

Other

Published
  • Genetic and Molecular Epidemiology
  • Internal Medicine
  • ISSN: 1938-3207
Paul Franks
E-mail: paul.franks [at] med.lu.se

Principal investigator

Genetic and Molecular Epidemiology

+46 40 39 11 49

60-12-021

33

Lund University Diabetes Centre, CRC, SUS Malmö, Entrance 72, House 91:12. SE-205 02 Malmö. Telephone: +46 40 39 10 00