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Macroporous gel particles as robust macroporous matrices for cell immobilization

Author:
  • Fatima Plieva
  • A Oknianska
  • Eva Degerman
  • Bo Mattiasson
Publishing year: 2008
Language: English
Pages: 410-417
Publication/Series: Biotechnology Journal
Volume: 3
Issue: 3
Document type: Journal article
Publisher: John Wiley & Sons

Abstract english

A new design of robust matrices for cell immobilization is described. Macroporous gels (MGs) with immobilized microbial cells were prepared at subzero temperatures and were formed inside a plastic core (so-called, protective housing). Due to the protective housing the macroporous gel particles with immobilized cells can be used in well-stirred bioreactors. High retained activity of yeast (77-92%) and Escherichia coli (50-91%) cells immobilized in MGs after drying and storage in the dried state was due to the high structural stability and heterogeneous porous structure of the MGs.

Keywords

  • Endocrinology and Diabetes

Other

Published
  • Insulin Signal Transduction
  • ISSN: 1860-6768
Eva Degerman
E-mail: eva.degerman [at] med.lu.se

Professor

Insulin Signal Transduction

+46 46 222 85 83

+46 70 885 83 62

BMC C1121b

66

Lund University Diabetes Centre, CRC, SUS Malmö, Entrance 72, House 91:12. SE-205 02 Malmö. Telephone: +46 40 39 10 00